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Sunday, 29 May 2016

Ahmad Masarwa

Ahmad Masarwa

Ahmad Masarwa

Assistant Professor (Senior Lecturer), Institute of Chemistry, The Hebrew University of Jerusalem


 
Ahmad Masarwa was born and grew up in Taibe, Israel. Then he moved to Haifa where he completed his undergraduate studies at the Technion- Israel Institute of Technology in Chemistry in 2005.
During his M.Sc. and Ph.D. studies, which were performed with Prof. Ilan Marek at the Technion, his research was focused on kinetic resolution, sigma-tropic rearrangements, carbometalation and the selective-cleavage of small, strained materials as a new entry to all-carbon quaternary stereogenic centers. As an illustrative example, they have applied these methodologies to the preparation of the simplest, unnatural, enantiomerically enriched, saturated hydrocarbon possessing a quaternary stereogenic center ((S)-[2H1, 2H2, 2H3]-neopentane). Masarwa was awarded the IUPAC-SOLVAY International Award for Young Chemists and the ICS-Israel Chemical Society Prize for his Ph.D. thesis.
After his Ph.D. studies, Masarwa joined the Department of Chemistry at the University of California, Berkeley in 2013 as a Rothschild and VATAT postdoctoral scholar under the supervision of Prof. Richmond Sarpong. He had worked on the application of metal-catalyzed selective C–C/ C–H bond activations of carvone-derived pinene scaffolds. This methodology can be used to access enantiopure natural product cores, such as those found in phomactin A and suaveolindol, as well as anticancer compounds in the taxoid family.
Ahmad completed his postdoctoral stay in October 2015. After this time, he started as a visiting scholar at the Hebrew University of Jerusalem. In July 2016, Masarwa started his tenure-track faculty position as an Assistant Professor (Senior Lecturer) at the Institute of Chemistry of the Hebrew University of Jerusalem.


The Hebrew University of Jerusalem Logo

Ahmad Masarwa Research Group

Organic and Organometallic Chemistry, Synthetic Organic Methodology Development, Chirality & Stereochemistry

Institute of Chemistry, The Hebrew University of Jerusalem
links
https://il.linkedin.com/in/ahmad-masarwa-b07a9886

Ahmad Masarwa
Ahmad Masarwa was born and grew up in Taibe, Israel. Then he moved to Haifa where he completed his undergraduate studies at the Technion- Israel Institute of Technology in Chemistry in 2005 (Cum lauda). In 2005 he joined the research group of Professor Marek as a M.Sc (Cum lauda) working towards the Enantioselective Preparation of Chiral Alkylidenecyclopropanes. In 2008, Ahmad started his PhD studies on the Selective Metal Mediated Carbon-Carbon Bond Cleavage of Strained Compounds: A New Approach to Enantiomerically Enriched All-Carbon Quaternary Stereocenters under the supervision of Professor Ilan Marek. During his studies at the Technion, Ahmad received several awards: e.g. Excellence in Teaching (Szego Prize for Excellent Instructor 2009 and for 2010), Excellence in studies and research (Jacobs Fellowship for Ph.D. students 2010-2011), Excellence in studies and research (Schulich fellowship and Prize for Ph.D. students 2012-2013), Excellence in Teaching (Schulich Prize for excellence in teaching 2011) and the ICS prize for outstanding Ph.D student (awarded by the Israel Chemical society 2012). In addition, Ahmad was awarded the prestigious Rothschild Post-Doctoral Fellowship (2013-2014), awarded by the Rothschild foundation for a post-doctoral position at the University of California, Berkeley with Prof. Sarpong where he is working in research on the chemical synthesis of bioactive molecules by applying C-C functionalization and cascade reaction processes.
Contact Information
Email: ahmadm@berkeley.edu

Experience

Assistant Professor of Chemistry

The Hebrew University of Jerusalem
– Present (5 months)Israel
https://scholars.huji.ac.il/masarwagroup

Postdoctoral Scholar

UC Berkeley
(2 years 6 months)United States
Ahmad was a post-doc at the University of California, Berkeley with Prof. Sarpong where he was working in research on the chemical synthesis of bioactive molecules by applying C-C functionalization and cascade reaction processes.

Education

Technion - Israel Institute of Technology

Doctor of Philosophy (PhD), Chemistry

Presentations & talks

 
 Papers and Posters Presented at International Meetings and Symposia:
  • Towards the Enantioselective Preparation of Chiral Alkylidenecyclopropanes. Samah Simaan, Ahmad Masarwa, Philipe Bertus and Ilan Marek.The 13th IUPAC International Symposium on Organometallic Chemistry Directed Towards Organic Synthesis, July 17-22, 2005, Geneva, Switzerland.
  • Towards the Enantioselective Preparation of Heterosubstituted Chiral Alkylidenecyclopropanes. Ahmad Masarwa, Amnon Stanger and Ilan Marek. The14th IUPAC International Symposium on Organometallic Chemistry Directed Towards Organic Synthesis, August 2-6, 2007, Nara, Japan.
  • Enantiomerically Pure Alkylidenecyclopropane Derivatives as a New Access to Cyclobutenes Possessing Quaternary Stereocenters. Ahmad Masarwa and Ilan Marek. The 12th European Symposium on Organic Reactivity (ESOR XII), September 6-11, 2009, Haifa, Israel.
  • Zirconocene-Mediated Ring-Opening of Alkylidenecyclopropane Derivatives. Ahmad Masarwa and Ilan Marek. The 9th International Symposium on Carbanion Chemistry (ISCC-9). July 20-24, 2010, Florence, Italy.
  • Selective Metal Mediated Carbon-Carbon Bond Cleavage of Strained Compounds: A New Approach to Enantiomerically Pure All-Carbon Quaternary Stereocenters. Ahmad Masarwa and Ilan Marek. The 13th Belgian Organic Synthesis Symposium (BOSS XIII), July 15-20, 2012, Leuven, Belgium.
  • Selective Metal-Mediated C–C Bond Activation of Strained Compounds: Application to Challenging non-Natural Product Synthesis. Ahmad Masarwa*. Ph.D. Thesis Essay: IUPAC, 2014.
  • The 2nd HUJI-IISC Joint meeting on Modern Chemistry. April 13th, 2016, at Hebrew University of Jerusalem, Israel, (Invited Oral presentation).
 
Posters and Talks Presented at National Meetings and Symposia:
  • The 70th-78th Meeting of the Israel Chemical Society, February, 2005-2013, Israel, nine Posters.
  • The 2nd National Graduate Student Symposium in Organic Chemistry. Department of Chemistry, Ben-Gurion University of the Negev, October 5, 2010, Negev, Israel, (Invited Oral presentation).
  • The 78th Meeting of the Israel Chemical Society, February, 2013, Israel, (Invited Oral presentation).
  • Hebrew University of Jerusalem, March, 2013, Israel. (Invited Oral presentation).
  • Ben-Gurion University of the Negev, November, 2015, Israel. (Invited Oral presentation).
  • Technion-Israel Institute of Technology, November, 2015, Israel. (Invited Oral presentation).
  • Weizmann Institute of Science, 2015, Israel. (Invited Oral presentation).
  • Hebrew University of Jerusalem, December, 2015, Israel. (Invited Oral presentation).
  • Tel-Aviv University, December, 2015, Israel. (Invited Oral presentation).

Honors and Awards

 
  • 2014: The IUPAC-SOLVAY International Award for Young Chemists.
  • 2013-2014: VATAT Postdoctoral Fellowship for Outstanding Postdoctoral Scholar. Awarded by The Israel Council for Higher Education.
  • 2013: Rothschild Postdoctoral Fellowship, Awarded by The Rothschild foundation (Yad Hanadiv).
  • 2012: The ICS Prize for being an Outstanding Ph.D. Student. Awarded by The Israel Chemical Society.
  • 2012: Schulich Award for Excellence in Teaching.
  • 2011-2012: Schulich Fellowship and Prize for being an Outstanding Ph.D. Student.
  • 2010-2011: Jacobs Fellowship for being an Outstanding Ph.D. student.
  • 2010: Sandor Szego award for being an Excellent Instructor.
  • 2009-2011: Schulich Fellowship and Prize for being an Outstanding M.Sc. Student.
  • 2009: Sandor Szego Prize for being an Excellent Instructor.
  • 2006-2007: Jacobs fellowship for being an Outstanding M.Sc. student.
  • 2005: Cum laude B.A. degree.
  • 2004: Technion-President’s Excellence Distinction.
  • 2003: Technion-Dean’s Excellence Distinction.
The Sarpong Group
8th Floor Latimer Hall
University of California, Berkeley
 


Asst. Prof. Ahmad Masarwa

 
Ahmad and his nephew Aodai
Ahmad with his nephew
 
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Wednesday, 25 May 2016

Shiraz Al-Shahrori



Shiraz Al-Shahrori

Shiraz Al-Shahrori

Regulatory Affairs Manager at Tabuk Pharmaceutical MFG Co

links



Experience


Regulatory Affairs Manager

Tabuk Pharmaceutical MFG Co
 – Present (1 year 9 months)

Business Development Project Manager - New Products MENA

Tabuk Pharmaceutical MFG Co
 –  (1 year 10 months)Amman - Jordan

Regulatory Affairs Quality Management

Tabuk Pharmaceutical MFG Co
 –  (11 months)Jordan - Amman
To assure the RA- MENA of delivering planned KPIs plus continuous improvement in RA- MENA deliverables (results of project management- KPIs and effectiveness).
This role is responsible for the overall success of KPI compliance and improvement for the RA- MENA. And also responsible for the RA- MENA data analysis reports in addition to the successful RA- MENA KPIs External/Internal audits.

RA Senior Team leader - MENA

Tabuk Pharmaceutical MFG Co
 –  (2 years)

RA Team Leader - MENA

Tabuk Pharmaceutical MFG Co
 –  (2 years 9 months)

Compliance Section Head

Hikma Pharmaceuticals
 –  (6 months)

RA Supervisor EU & US

Advanced Pharma
 –  (5 months)

Compliance Officer

JPM
 –  (2 years 8 months)

R&D Analyst

JPM
 –  (3 years 1 month)

Education


JUST

Bachelor of Science (BSc), Applied Chemistry, Very good with first grade





Tabuk Pharmaceutical Manufacturing Company has announced plans to increase its female employee intake in the next 5 years; by hiring 200-300 additional ...
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Tuesday, 24 May 2016

Hema Nair

Hema Nair

Hema Nair

Associate Professor at Shri Venkateshwara College of Pharmacy



Hema Nair, PhD in Pharmaceutics from Mumbai University, Diploma in Patent Law, Nalsar University, Hyderabad, is currently Associate Professor of Pharmaceutics at Sri Venkateshwara College of Pharmacy, Hyderabad, India. She has 15 years of teaching experience at Bombay College of Pharmacy, Mumbai. Her key research areas include drug delivery systems-conventional & novel, synthesis and evaluation of novel polymeric excipient materials. She has around 10 research projects both Government & Industry sponsored. She has published 14 research articles in both national & international journals and participated in more than 33 conferences. She is currently a reviewer for several national and international journals.


links


Experience



Associate Professor

Shri Venkateshwara College of Pharmacy
 – Present (9 months)Hyderabad Area, India


Faculty

Bombay College of Pharmacy
 –  (15 years)

Education



Bombay College of Pharmacy

MPharm, Pharmaceutics


8th Indo Global summit and Expo onVaccines, Therapeutics & Healthcare (VTH-2015)November 02-04, 2015 HICC, Hyderabad, India




Hema Nair

Sri Venkateshwara College of Pharmacy, India
Title: Polymeric micelle based formulation for delivery of docetaxel: Development and evaluation

Biography

Hema Nair, PhD in Pharmaceutics from Mumbai University, Diploma in Patent Law, Nalsar University, Hyderabad, is currently Associate Professor of Pharmaceutics at Sri Venkateshwara College of Pharmacy, Hyderabad, India. She has 15 years of teaching experience at Bombay College of Pharmacy, Mumbai. Her key research areas include drug delivery systems-conventional & novel, synthesis and evaluation of novel polymeric excipient materials. She has around 10 research projects both Government & Industry sponsored. She has published 14 research articles in both national & international journals and participated in more than 33 conferences. She is currently a reviewer for several national and international journals.

Abstract

Cancer therapy has seen enormous growth in the last few decades in terms of new molecules and novel targeted formulations making a successful entry into the treatment paradigm. The semisynthetic taxane derivative, docetaxel holds great promise in treating solid tumours. However, owing to poor solubility of docetaxel in aqueous milieu, it is formulated as a solution in polysorbate 80, TaxotereÃ’. The solubilizer (polysorbate 80) used, is associated with side effects like hypersensitivity reactions which demand co-administration of dexamethasone. This in turn, compromises immunity of cancer patients, often resulting in discontinuation of docetaxel treatment. The inability to target tumour tissues is another limitation of TaxotereÃ’. In the light of the drawbacks associated with existing docetaxel therapy, the current study presents development of alternative formulations based on polymeric micelles fabricated using biodegradable polymers. Initially, polyethylene glycol-polycaprolactone amphiphilic copolymers of different molecular weights were synthesized by ring opening bulk polymerization and the products characterized (through IR, H1-NMR, XRD, DSC and measurement of critical micelle concentrations). These, in turn, were employed in the preparation of micellar systems containing solubilized docetaxel. The resultant micellar dispersions were characterized for particle size and zeta potential, drug content and efficiency of entrapment of docetaxel, morphology by TEM and for in vitro release studies. The biodegradable copolymers used to fabricate these systems were found to possess low CMC values, thereby conferring resistance to breakdown on dilution encountered in bloodstream in vivo. Also, in vitro cytotoxicity as evaluated in non-small cell lung cancer cell line A549 demonstrated that simple and mixed micelles were as effective as docetaxel solution and bore potential to be used as substituents for polysorbate 80 based formulations.
Hema Nair | OMICS International
Hema Nair | OMICS International
Hema Nair | OMICS International
Hema Nair | OMICS International

Speaker Presentations






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