Johannes Kaschel

Research Scientist Medicinal Chemistry at AbbVie

• https://de.linkedin.com/in/johannes-kaschel-86a281a9/en

Experience

Research Scientist Medicinal Chemistry

AbbVie

July 2015 – Present (11 months)Ludwigshafen

R&D:
- Chemistry in micelles (organic synthesis, catalysis)
- Neuroscience discovery

Postdoc

TU Braunschweig

January 2015 – June 2015 (6 months)

Electrophilic alkynylations with hypervalent iodine reagents

(Open)1 honor or award

Postdoc

UC Berkeley

January 2014 – December 2014 (1 year)

Total synthesis of indole alkaloids (organic synthesis; total synthesis)

(Open)1 honor or award

Postdoc

TU Braunschweig

September 2013 – November 2013 (3 months)

Donor-acceptor cyclopropanes in organic synthesis

PHD Student

Georg-August-Universität Göttingen

January 2010 – July 2013 (3 years 7 months)

Rearrangement reactions of donor-acceptor cyclopropanes (organic synthesis; methodology)

Honors & Awards

Postdoctoral fellowship

German Research Foundation (DFG)

January 2014

Postdoctoral fellowship

German Research Foundation (DFG)

January 2015

Publications

Ethynyl Benziodoxolone (EBX): Installing Alkynes the Reversed Way(Link)

Angew. Chem. Int. Ed. 2015, 54, 8876–8878

A New Golden Age for Donor-Acceptor Cyclopropanes(Link)

Angew. Chem. Int. Ed. 2014, 53, 5504-5523.

Donor-Substituted Nitrocyclopropanes: Immediate Ring-Enlargement to Cyclic Nitronates(Link)

Org. Lett. 2013, 15, 6098-6101

(Open)

Rearrangements of Furan-, Thiophene- and N-Boc-Pyrrole-Derived Donor-Acceptor Cyclopropanes: Scope and Limitations(Link)

Eur. J. Org. Chem. 2013, 4539-4551

Donor-acceptor cyclopropanes with Lawesson’s and Woollins’ reagents: formation of bisthiophenes and unprecedented cage-like molecules(Link)

Chem. Commun. 2013, 49, 4403-4405

Symmetric and unsymmetric 3,3’-linked bispyrroles via ring-enlargement reactions of furan-derived donor-acceptor cyclopropanes(Link)

Org. Biomol. Chem. 2013, 11, 3494-3509

Domino Reactions of Donor-Acceptor-Substituted Cyclopropanes for the Synthesis of 3,3’-Linked Oligopyrroles and Pyrrolo[3,2-e]indoles(Link)

Angew. Chem. Int. Ed. 2012, 51, 11153-11156

(Open)

One Pot - Two Phases: Iron-Catalyzed Cyclopropanation with in Situ Generated Diazomethane(Link)

Angew. Chem. Int. Ed. 2012, 51, 7085-7086

Total Synthesis of a-Linked Rha-Rha-Gal Undecaprenyl Diphosphate Found in Geobacillus stearothermophilus(Link)

Eur. J. Org. Chem. 2011, 6233-6239

Kleine Ringe erweitern: Auf die Spannung kommt es an(Link)

Nachrichten aus der Chemie 2011, 59, 729-733

2 authors

• 

  Johannes Kaschel

  Research Scientist Medicinal Chemistry at AbbVie

• 

  Daniel B. Werz

From Furan to Molecular Stairs: Syntheses, Structural Properties and Theoretical Investigations of Oligocyclic Oligoacetals(Link)

Chem. Eur. J. 2010, 16, 11276-11288

(Open)

anti-Oligoanellated THFMoieties: Synthesis via Push-Pull-Substituted Cyclopropanes(Link)

Org. Lett. 2009, 11, 2317-2320

Education

Georg-August-Universität Göttingen

Diplom, Chemie

2005 – 2009

Johannes Kaschel

Ph.D.: U. of Goettingen

Currently: AbbVie

Joined in: 2014   Johannes Kaschel  Johannes grew up in Wolfenbuettel, Germany. For his studies of chemistry he moved to Goettingen, Germany, where he joined the group of Prof. D. B. Werz to investigate rearrangement reactions of donor-acceptor cyclopropanes. Since January 2014, Johannes has been a member of the Sarpong group with a Postdoctoral-Fellowship from the German Research Foundation (DFG) working on the total synthesis of indole alkaloids.  Contact Information  Email:jkaschel at berkeley dot edu

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