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Showing posts with label United States. Show all posts
Showing posts with label United States. Show all posts

Saturday, 24 October 2015

Martin Tremblay



Martin Tremblay

Martin Tremblay

Sr. Director,  Chemistry, Infinity Pharmaceuticals

Infinity Pharmaceuticals Inc
784 Memorial Drive
Cambridge , Massachusetts 02139
United States 

Phone: 617-453-1268. Fax: 617-682-1418.
E-mail: Martin.Tremblay@infi.com.

 Infinity Pharmaceuticals, Inc


LINKS
https://www.linkedin.com/pub/martin-tremblay/4/a13/976
http://www.pubfacts.com/author/Martin+R+Tremblay
https://www.researchgate.net/profile/Martin_Tremblay3
View Larger Map INFINITY PHARMA
http://www.infi.com/contact-us/

Summary

Infinity Pharmaceuticals, Inc.: Demonstrated organizational and scientific leadership for the discovery and development of innovative drugs in oncology and inflammation; Key player in the discovery and development of saridegib (IPI-926)

 Saridegib...........http://newdrugapprovals.org/2015/09/11/ipi-926-saridegib/
Saridegib.svgSaridegib3Dan.gif

Eisai, Inc.: Synthesis of natural products-based libraries; Total synthesis of marine natural product laulimalide.

The Scripps Research Institute: Design and synthesis of haptens for the production of catalytic antibodies.

Université Laval: Solution and solid-phase synthesis of estrogen receptor antagonists and inhibitors of steroid biosynthesis

Experience




Sr. Director Chemistry

Infinity Pharmaceuticals
– Present (8 months)








Director

Infinity Pharmaceuticals
(3 years 1 month)Cambridge, MA








Associate Director, Chemistry

Infinity Pharmaceuticals
(3 years 8 months)Cambridge, MA





Lead Sr. Scientist

Infinity Pharmaceuticals
(1 year 9 months)Cambridge, MA





Sr. Scientist

Infinity Pharmaceuticals
(2 years 5 months)Cambridge, MA




Sr. Research Investigator

Eisai
(1 year)Andover, MA




Research Investigator

Eisai
(1 year 10 months)Andover, MA



Education




The Scripps Research Institute

Postdoctoral, Chemistry




Infinity Pharmaceuticals, 784 Memorial Drive, Cambridge, Massachusetts 02139, United States

 Infinity Pharmaceuticals, Inc


 Image
Map of Infinity Pharmaceuticals
The mission of Infinity Pharmaceuticals, Inc. is to discover, develop, and deliver to patients best-in-class medicines for the treatment of difficult-to-treat diseases, with a strong focus in oncology and inflammation.

Small molecule discovery and development capabilities
Infinity’s programs arise from the integration of a broad range of research and development capabilities, including strengths in cancer biology, medicinal chemistry, clinical and translational medicine, and drug product process development and formulation.

Strategic alliances
Building on its strengths in innovative small molecule drug discovery and development, Infinity has established significant alliances with leading pharmaceutical and biotechnology companies to help realize the full potential of its product pipeline.

Business and scientific expertise
The company has assembled a team of passionate, committed, and innovative individuals who bring together their collective expertise in all areas of business and drug discovery and development.

Culture of Citizen-Ownership
Infinity’s culture and environment of Citizen-Ownership is as important as its technologies. Infinity works together as a community with the shared goal of bringing important new medicines to patients.

Specialties

Oncology, small molecule, fully integrated
  • Website

    http://www.infi.com
  • Industry

    Pharmaceuticals
  • Type

    Public Company
  • Headquarters

    784 Memorial Drive Cambridge, MA United States
  • Company Size

    51-200 employees
  • Founded

    2001
 Infinity is an innovative biopharmaceutical company dedicated to discovering, developing and delivering best-in-class medicines to people with difficult-to-treat diseases. We have assembled an experienced team with a track record of success, a passion for science and a commitment to developing terrapins to address important medical needs.





Learn about the science behind duvelisib
 
 


 




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Thursday, 1 October 2015

PRATIMA PATIL

Pratima Patil

Pratima Patil

PhD. in Biological Sciences,University of Delaware

https://www.facebook.com/pratima.patil.969

 

Summary

Recently graduated with a PhD from University of Delaware. Developed 3D culture model to mimic components of the tumor micro-environment and investigate the impact of tumor cells on normal epithelial cells. Worked in the pharmaceutical R&D area for 4 years where I developed and optimized cell free and cell based assays to evaluate efficacy and potency of potential drug candidates in different assay formats.Over the years I have gained expertise in molecular biology, protein biochemistry and confocal microscopy techniques.

Experience




Research Assistant

Nemours
August 2010 – Present (5 years 3 months)Wilmington,Delaware



PHD Graduate Student

University of Delaware
December 2009 – Present (5 years 11 months)United States
For my doctoral research project, I have been studying the early events that lead to tumor formation, particularly how tumor cells affect normal epithelial cell morphology.
Developed novel 3D assay system to study preneoplastic lumen filling in vitro and to quantify the pro-oncogenic effects of soluble E-cadherin, a tumor promoting protein fragment which is elevated in epithelial cancers.



Associate Research Scientist

Advinus Therapeutics Pvt. Ltd.
May 2007 – November 2009 (2 years 7 months)India
• Developed in vitro assays to screen for potential drug candidates against various biological targets in inflammatory diseases and metabolic disorders
• Developed secondary cell-based fluorimetric assays for measuring intracellular calcium mobilization and cAMP to screen for activity of GPCR modulators
• Developed radiometric assays to screen for modulators of metabolite transporters



Assistant Research Scientist

Advinus Therapeutics- A TATA Enterprise
December 2005 – May 2007 (1 year 6 months)India
•Routinely screened compounds in cell-free enzymatic assays using absorption and fluorescence readouts
•Gained experience in protein expression (prokaryotic systems), protein isolation and purification using various chromatography techniques

Education




University of Delaware

Doctor of Philosophy (Ph.D.), Cell/Cellular and Molecular Biology
2010 – 2015
Dissertation Title: 'Soluble E-cadherin as a Microenvironmental Factor which Enhances Tumor Progression'



Vellore Institute of Technology

Master's degree, Biomedical Genetics
2003 – 2005

Education

School:University Of Delaware - Newark, DE     2000 to 2003
Ph.d. in biological sciences
School:Nagpur University - Nagpur, Maharashtra     2003
Bachelor of science
School:Vellore Institute Of Technology - Vellore, Tamil Nadu
Master's in biomedical genetics
School:Chemistry In Nagpur University


University of Delaware

Map of university of delaware









vellore institute of technology
Map of vit university



Newark, United States






WILMINGTON DELAWARE
Map of wilmington de

////Newark, United States, vellore institute of technology, pratima patil, delaware,