DR ANTHONY MELVIN CRASTO,WorldDrugTracker, helping millions, A 90 % paralysed man in action for you, I am suffering from transverse mylitis and bound to a wheel chair,With death on the horizon, This will not stop me, Gods call only..........
DR ANTHONY MELVIN CRASTO Ph.D ( ICT, Mumbai) , INDIA 29Yrs Exp. in the feld of Organic Chemistry,Working for GLENMARK PHARMA at Navi Mumbai, INDIA. Serving chemists around the world. Helping them with websites on Chemistry.Million hits on google, world acclamation from industry, academia, drug authorities for websites, blogs and educational contributio
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Friday, 25 August 2017

Best World Drug Tracker Award 7 th July 2017 Taj land ends, Bandra, Mumbai India








On 7 th July 2017 Receiving Best Worlddrugtracker Award for lifetime acheivement in Pharma... The venue...Taj land ends, Bandra, Mumbai India

“Times Influence presents National Marketing Excellence Awards ( For Excellence in Healthcare)” schedule on 7th July, 2017 at Taj Lands End, Bandra, Mumbai. India


Thursday, 24 August 2017

Lifetime achievement award, WHC17, in Hyderabad, India 22 Aug 2017






Lifetime achievement award ........WORLD HEALTH CONGRESS 2017 in Hyderabad, 22 aug 2017 at JNTUH KUKATPALLY. HYDERABAD, TELANGANA, INDIA, Award given by Dr. M Sunitha Reddy Head of the Department, Centre for Pharmaceutical Sciences, Institute of Science &Technology, JNTU-H, Kukatpally, Hyderabad, India






Speaking at World health congress 2017....JNTUH Hyderabad 22 aug 2017









Thursday, 22 June 2017

Naresh Kumar

Naresh Kumar

Naresh Kumar

M.Sc. Punj., Ph.D. W'gong., CChem, MRACI
Professor
Contact details
Phone: +61 2 9385 4698
Email: n.kumar@unsw.edu.au

Office

Room 224, Dalton Building
UNSW, Kensington, 2052

Research Group Website

 

Biographical Details

PhD in Organic Chemistry from Wollongong University, 1983; Postdoctoral Research Fellow in Organic Chemistry, University of New South Wales, 1983 - 1985; Professional Officer, Organic Chemistry, UNSW 1985 - 1995; Project Scientist 1995 - 2003; Lecturer 2003 - 2008; Associate Professor 2008 - 2012; Professor 2013 - present.

Research Interests

Natural products chemistry. Development of new synthetic methodologies for the preparation of biologically important natural products and their analogues. Novel antimicrobial biomaterials. Heterocyclic chemistry. Medicinal chemistry. Design and synthesis of quorum-sensing inhibitors.

Selected Publications

(Career total publications = 180)
▪   Zhang R, Iskander G, da Dilva P, Chan D, Vignevich V, Nguyen V, Bhadbhade M, Black D, Kumar N, Synthesis of new aryl substituted furan-2(5H)-ones using the Suzuki-Miyaura reaction, Tetrahedron, 2011, 67, 3010-3016.
▪   Cheah WC,Wood K, Black DStC, and Kumar N, Facile ring-opening of N-acylisatins for the development of novel peptidomimetics. Tetrahedron, 2011, 67, 7603-7610.
▪   Devakaram R, Black DStC, Andrews KT, Fisher GM, Davis RA, Kumar N, Synthesis and antimalarial evaluation of novel benzopyrano[4,3-b]benzopyran derivatives. Bioorganic & Medicinal Chemistry, 2011,19, 5199-5206.
▪   Chen, R., Willcox M. D. P., Cole, N., Ho, K. K. K., Rasul, R., Denman, J. A., and Kumar, N., (2012) Characterization of chemoselective surface attachment of the cationic peptide melimine and its effects on antimicrobial activity. Acta Biomaterialia, 2012, 8, 4371-4379.
▪   Suryanti, V., Bhadbhade, M., Bishop, R., Black, D. StC., and Kumar, N. Self-assembly of alkyl N-acetylglyoxylic amides of varying chain lengths. CrystEngComm. 2012, 14, 7345-7354.
▪   Gardner, C. R., Cheung, B. B., Koach, J., Black, D. StC., Marshall, G. M., and Kumar, N. Synthesis of retinoid enhancers based on 2-aminobenzothiazoles for anti-cancer therapy. Bioorganic & Medicinal Chemistry, 2012, 20, 6877-6884.
▪   Ho K, Cole N, Chen R, Willcox MDP, Rice S, Kumar, N. Immobilisation of antibacterial dihydropyrrol-2-ones onto functional polymer supports to prevent bacterial infections in vivo, Antimicrobial Agents and Chemotherapy, 2012, 56, 1138-1141.
▪   Kutty, S. K., Barraud, N., Pham, A., Iskander, G., Rice, S. A., Black, D., StC.; Kumar, N. Design, Synthesis, and Evaluation of Fimbrolide-Nitric Oxide Donor Hybrids as Antimicrobial Agents, Journal of Medicinal Chemistry, 2013, 56, 9517-9529.
▪   Eugene MH, Pasqueir E, Iskander G, Black DStC, and Kumar N, Synthesis of novel isoflavene-propranolol hybrids as anti-tumor agents, Bioorganic &. Medicinal Chemistry, 2013, 21,1652-1660
▪   Ho, K. K. K., Chen, R., Willcox, M. D. P., Rice, S. A., Cole, N, Iskander, G., Kumar, N. (2014) Quorum sensing inhibitory activities of surface immobilized antibacterial dihydropyrrolones via click chemistry, Biomaterials, 2014, 35, 2336-2345.
▪   Mielczarek, M., Devakaram, R. V., Ma, C., Yang, X., Kandemir, H., Purwono, B., Black, D. StC., Griffith, R., Lewis, P. J., Kumar, N., Synthesis and biological activity of novel bis-indole inhibitors of bacterial transcription initiation complex formation, Organic & Biomolecular Chemistry, 2014, 12, 2882-2882.
▪   Kutty, SK, Barraud N, Ho, KKK, Iskander GM, Griffith R, Rice S, Bhadbhade M, Willcox M, Black DStC, Kumar N., Hybrids of acylated homoserine lactone and nitric oxide donors as inhibitors of quorum sensing and virulence factors in Pseudomonas aeruginosaOrganic & Biomolecular Chemistry, 2015, 13, 9850-9861.
▪   Ho, K. K., Kutty, S., Chan, D., Chen, R., Willcox, M., Kumar, N., (2015) Development of Fimbrolides, Halogenated Furanones and their Analogues as Antimicrobial Agents, In E. Ivanova and R. Crawford (Eds): Antibacterial Surface Design, Springer International, 149-170.
▪   Hong, K, Ball G, Black DStC, Kumar, N., The Mosaic of Rotterlin, J. Org. Chem, 2015, 80, 10668-10674.
▪   Chen R, Willcox MDP, Ho KKK, Smyth D, Kumar N., Antimicrobial peptide melimine coating for titanium and its in vivo antibacterial activity in rodent subcutaneous infection models. Biomaterials, 2016, 85, 142-151.
▪   Nizalapur S, Kimyon O, Biswas NN, Gardner CR, Griffith R, Rice S, Manefield M, Willcox M, Black DStC, Kumar N., Design, synthesis and evaluation of N-arylglyoxylamides derivatives as structurally novel bacterial quorum sensing inhibitors, Organic & Biomolecular Chemistry, 2016, 14, 680-693.

Neeraj Sharma

Neeraj Sharma

Neeraj Sharma

B.Sc. (Adv.) (Hons) Sydney 2005, Ph.D. Sydney 2010, MRACI
Senior Lecturer & ARC DECRA Fellow

Contact details

Phone: +61 2 9385 4714
Email: neeraj.sharma@unsw.edu.au

Office

Room 216, Dalton Building
UNSW, Kensington, 2052

Research Group Website

 

Biographical Details

Bachelor of Advanced Science (Honours Class 1), The University of Sydney, 2002-2005. Ph.D. in Chemistry, The University of Sydney, 2006-2009. Postdoctoral researcher, The Bragg Institute, Australian Nuclear Science and Technology Organisation 2009-2012. Australian Institute of Nuclear Science and Engineering (AINSE) Research Fellowship and appointed Lecturer in Chemistry, UNSW, 2012.

Research Interests

Solid state and Materials Chemistry
Energy-related devices such as batteries and fuel cells are essential in our lives. In order to develop the next generation of technologies we need more power, or better performance, at a lower environmental cost. Research into understanding the interplay between the crystal structure of new materials and their physical properties will allow us to revolutionise how we obtain and store energy.
My research approach encompasses exploratory synthesis, structural determination, physical property measurements and in situ structure and property characterisation of batteries and other devices.
Towards the next generation of batteries: Sodium-ion batteries
Lithium-ion batteries are ubiquitous in our daily lives, e.g. mobile phones and laptop computers, but their limitations have restricted wide-scale use in applications requiring higher power, e.g. electric vehicles and energy storage of renewable energy. This project will target new battery chemistries, in particular sodium-ion batteries, by developing and characterizing new electrode and electrolyte materials. We will work to develop a reliable and affordable room-temperature sodium-ion battery to provide sufficient power for large-scale energy storage from intermittent renewable power sources. Students will work on one of the following parts of a battery and test their component in idealized batteries.
  • Positive electrode materials
These electrodes provide the source of the sodium-ions and represent the largest cost and energy limitations for lithium-ion batteries. Here, new sodium-containing transition metal oxides, phosphates or sulfates are be synthesized and characterized to determine the relationship between crystal structure and battery performance.
  • Electrolytes
Sodium-ion conducting ceramics or glassy-ceramics are known to be excellent electrolytes at high temperatures (>300°C). We work towards making materials with sufficient sodium-ion conduction at room temperature.
  • Negative electrode materials
Negative electrodes are the least investigated component in a sodium-ion battery and the compounds used for lithium-ion batteries show poor performance in sodium-ion batteries. By developing new negative electrodes and understanding their limitations towards reversible sodium insertion/extraction we will be enable the next generation of devices. The focus of these projects are carbon based materials and the use of solid state 23Na NMR to characterise the insertion/extraction processes.
New: Tuning negative thermal expansion to produce zero thermal expansion materials
The majority of materials expand during heating via thermal expansion and this process is responsible for billions of dollars per year in maintenance, re-manufacture and replacement costs due to wear and tear on both moving parts (e.g. in aircraft gas turbines), and components that are designed to be static (e.g. in optics, coatings, electronics). If a zero thermal expansion (ZTE) material can be made, a material that neither expands nor contracts upon heating, this could dramatically reduce industrial costs. In order to achieve this, the opposite extreme of materials are considered in this project - negative thermal expansion (NTE) is a property exhibited by a small group of materials predominantly due to transverse vibrations of atom groups or cooperative rotations of units (e.g. –CN- or WO4). These materials typically feature large crystallographic voids and cations with variable oxidation states. So why not use a battery as a synthesis tool? In this project we will controllably insert Li and Na into the voids of the NTE materials, via a battery, in order to tune the cooperative rotations to produce ZTE materials.
In situ studies of materials
Investigating materials functioning in actual devices, i.e. in situ, allows the direct comparison of device performance to the atomic-level changes in the material. By manipulating the atomic-scale crystal structure of components, using a variety of synthetic techniques, improvements in device performance can be achieved, e.g. better lithium-ion batteries can be made.
In a lithium-ion battery, the charge process is characterised by the removal of lithium from the cathode, while on discharge lithium is inserted into the cathode. The cathode above features relatively small crystal-structure changes with the lithium insertion/extraction (top) making it an attractive material for commercial applications. The information on crystal-structure evolution is derived from in situ neutron powder diffraction data (bottom left) during charge/discharge cycling of the battery. The battery (bottom right) was fabricated by collaborators in Fudan University, China.
Development of new ionic conductors
Full solid-state devices are more advantageous than liquid-containing devices as they are generally safer and more robust under harsh conditions however limitations arise particularly due to the lower ionic conductivity in solids. Exploring the mechanism of ionic conduction in solids, and its relationship to factors such as temperature and dopant concentration is a method to significantly improve solid-state devices.
An example of ‘watching’ a synthesis reaction using neutron powder diffraction. Starting materials are placed on the diffractometer and the synthesis procedures are initiated while neutron powder diffraction patterns are continuously collected. For Li6PS5Cl the synthesis temperature is found to have a significant influence on the ionic conduction properties.
Structural investigations using neutron and X-ray scattering
Single crystal, solid-state and electrochemical synthetic techniques can be used to tailor-make new materials for specific applications, but critical to this process is the characterisation tools employed to elucidate the arrangement of atoms. Our use of the Australian Synchrotron and the neutron scattering facilities at ANSTO provide unparalleled insight into these materials.

Selected Publications

Towards the next generation of batteries: Sodium-ion batteries
  • N. Sharma, N. Tapia-Ruiz, G. Singh, A. R. Armstrong, J. C. Pramudita, H. E. A. Brand, J. Billaud, P. G. Bruce, T. Rojo, Rate dependent performance related to crystal structure evolution of Na0.67Mn0.8Mg0.2O2in a sodium-ion battery, Chemistry of Materials, 27, 6976−6986 (2015)
  • V. Palomares, P. Serras, H.E.A. Brand, T. Rojo, N. SharmaStructural evolution of mixed valent (V3+/V4+) and V4+ sodium vanadium fluorophosphates as cathodes in sodium-ion batteries: Comparisons, overcharging and mid-term cycling, Journal of Materials Chemistry A, 3, 23017-23027 (2015)
  • N. Sharma, M. H. Han, J. C. Pramudita, E. Gonzalo, H. E. A. Brand, T. Rojo, A comprehensive picture of the current rate dependence on the structural evolution of P2-Na2/3Fe2/3Mn1/3O2, Journal of Materials Chemistry A, 3, 21023–21038 (2015)
  • N. Sharma, E. Gonzalo, J. C. Pramudita, M. H. Han, H. E. A. Brand, J. N. Hart, W. K. Pang, Z. Guo, T. Rojo, The unique structural evolution of the O3-phase Na2/3Fe2/3Mn1/3O2 during high rate charge/discharge: A sodium-centred perspective, Advanced Functional Materials, 25, 4994-5005 (2015)
  • J. C. Pramudita, S. Schmid, T. Godfrey, T. Whittle, M. Alam, T. Hanley, H. E. A. Brand, N. SharmaSodium uptake in cell construction and subsequent in operando electrode behaviour of Prussian Blue Analogues, Fe[Fe(CN)6]1-x×yH2O and FeCo(CN)6, Physical Chemistry Chemical Physics, 16, 24178-24187 (2014)
In situ studies on materials
Reviews & books
  • N. Sharma, M. Wagemaker, “Lithium-Ion Batteries” in Neutron Applications in Materials for Energy, GJ Kearley, VK Peterson (Ed), Springer, p139-203, http://link.springer.com/chapter/10.1007/978-3-319-06656-1_7
  • N. Sharma, W. K. Pang, Z. Guo, V. K. Peterson, In situ powder diffraction studies of electrode materials in rechargeable batteries, ChemSusChem, 8, 2826 – 2853 (2015)
Journal articles
  • J. Li, R. Petibon, S. Glazier, N. Sharma, W. K. Pang, V. K. Peterson, J. R. Dahn, In-situ Neutron Diffraction Study of a High Voltage Li(Ni0.42Mn0.42Co0.16)O2/Graphite Pouch Cell, Electrochimica Acta, 180, 234–240 (2015)
  • N. Sharma, G. Du, Z. Guo, J. Wang, Z. Wang, V. K. Peterson, Direct evidence of concurrent solid-solution and two-phase reactions and the non-equilibrium structural evolution of LiFePO4, Journal of the American Chemical Society, 134, 7867-7873 (2012)
  • N. Sharma, V. K. Peterson, In situ neutron diffraction experiments on lithium-ion batteries, Journal of Solid State Electrochemistry, 16, 1849-1856, (2012)
  • G. Du, N. Sharma, V. K. Peterson, J. Kimpton, Z. Guo, Br-doped Li5Ti4O12 and composite TiO2 anodes for Li-ion batteries: Synchrotron X-ray and in-situ neutron diffraction studies, Advanced Functional Materials, 21, 3990-3997, (2011)
  • N. Sharma, M. V. Reddy, G. Du, S. Adams, G. V. Subba Rao, B. V. R. Chowdari, Z. Guo, V. K. Peterson, Time-dependent in-situ neutron diffraction investigation of Li(Co0.16Mn1.84)O4 cathode, Journal of Physical Chemistry C, 115, 21473-21480, (2011)
  • N. Sharma, G. Du, A. J. Studer, Z. Guo, V. K. Peterson, Structure of the MoS2 anode within a Li-ion battery during discharge: in-situ neutron diffraction studies using an optimised cell design, Solid State Ionics, 199-200, 37-43, (2011)
  • N. Sharma, V. K. Peterson, M. M. Elcombe, M. Avdeev, A. J. Studer, N. Blagojevic, R. Yusoff, N. Kamarulzaman, Structural changes in a commercial lithium ion battery during electrochemical cycling: An in-situ neutron diffraction study, Journal of Power Sources, 195, 8258-8266 (2010)
Development of new ionic conductors
  • D. Safanama, N. Sharma, R. Prasada Rao, H. E. A. Brand and S. Adams, Structural evolution of NASICON-type Li1+xAlxGe2-x(PO4)3 using in situ synchrotron X-ray powder diffraction, Journal of Materials Chemistry A, 2016, DOI:10.1039/C6TA00402D, Accepted April 2016
  • R.P. Rao, W. Gu, N. Sharma, V.K. Peterson, M. Avdeev, S. Adams, In situ Neutron Diffraction Monitoring of Li7La3Zr2O12 formation: Towards a Rational Synthesis of Garnet Solid Electrolytes, Chemistry of Materials, 27, 2903–2910 (2015)
Structural investigations using neutron and X-ray scattering
  • R.J. Gummow, N. Sharma, V.K. Peterson and Y. He, Crystal chemistry of the Pmnb polymorph of Li2MnSiO4, Journal of Solid State Chemistry 188, 32-37, (2012) - Journal cover
  • W. Miiller, Q. Zhou, N. Sharma, M. Avdeev, R. Kutteh, G. J. Kearley, B. J. Kennedy, S. A. Schmid and C. D. Ling, An extraordinary magnetoelastic effect in Ba3BiIr2O9 due to coincident magnetic dimerisation and structural antidimerisation, Journal of the American Chemical Society, 134, 3265-3270 (2012)
  • N. Sharma, R. B. Macquart, M. Avdeev, M. Christensen, G. J. McIntyre, Y. Chen, C. D. Ling, Re-investigation of the Structure and Crystal Chemistry of the Bi2O3-W2O6 'Type Ib' Solid Solution Using Single Crystal Neutron and Synchrotron X-ray Diffraction, Acta Crystallographica Section, B66, p165-172 (2010)
  • N. Sharma, G. E. Wrighter, P. Y. Chen, B. J. Kennedy, P. L. Lee, C. D. Ling, Three-layer Aurivillius phases containing magnetic transition metal cations: Bi(2-x)Sr(2+x)(Nb,Ta)(2+x)M(1-x)O12, M=Ru4+, Ir4+, Mn4+, x≈0.5, Journal of Solid State Chemistry, 180, p370-376 (2007)

Friday, 5 May 2017

Dr. Dnyaneshwar B. Gophane, Ph. D.

STR1

Dr. Dnyaneshwar B. Gophane, Ph. D.
Post doc fellow at Purdue university and university of Iceland
Email, gophane@gmail.com
Dr. Dnyaneshwar B. Gophane completed his B.Sc. (Chemistry) at Anand college of science, Pathardi (Ahmednagar, Maharashtra, India) in 2000 and M.Sc. (Organic Chemistry) at Department of Chemistry, University of Pune (India) in 2003. From 2003 to 2008, he worked in research and development departments of pharmaceutical companies like Dr. Reddy’s Laboratories and Nicholas Piramal India Limited, where he involved in synthesizing novel organic compounds for in vitro and in vivo screening and optimizing process for drug molecule syntheses. In 2008, Dnyaneshwar joined Prof. Sigurdsson’s laboratory for his Ph.D. study at the University of Iceland. 
His Ph.D. thesis mainly describes syntheses of nitroxide spin-labeled and fluorescent nucleosides and their incorporation into DNA and RNA using phosphoramidite chemistry. These modified nucleosides are useful probes for studying the structure and dynamics of nucleic acids by EPR and fluorescence spectroscopies. In 2014, after finishing his Ph.D., he worked as post doc fellow in same laboratory and mainly worked on spin labelling of RNA. 
At the university of Purdue in his second post doc, he was totally dedicated to syntheses of small molecules for anti-cancer activity and modification of cyclic dinucleotides for antibacterial activity. During his research experience, he has authored 8 international publications in peer reviewed journals like Chemical Communications, Chemistry- A European Journal, Journal of organic chemistry and Organic and Biomolecular Chemistry.

Intro


B.Sc. (Chemistry) at Anand college of science, Pathardi (Ahmednagar, Maharashtra, India) in 2000 
M.Sc. (Organic Chemistry) at Department of Chemistry, University of Pune (India) in 2003
2003 to 2008, he worked in research and development departments of pharmaceutical companies like Dr. Reddy’s Laboratories and Nicholas Piramal India Limited
2008, Dnyaneshwar joined Prof. Sigurdsson’s laboratory for his Ph.D. study at the University of Iceland.
At the university of Purdue in his second post doc

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Dr. Vinayak Pagar


Dr. Vinayak Pagar

Dr. Vinayak Pagar

Postdoctoral Research Fellow at The Ohio State University


Vinayak Vishnu Pagar was born in Nasik, Maharashtra (India) in 1983. He obtained his BSc and MSc degrees in chemistry from the University of Pune (India) in 2004 and 2006, respectively. From 2006–2010, he worked as Research Associate in pharmaceutical companies like Jubilant Chemsys Ltd. and Ranbaxy Laboratories Ltd. (India). In 2010, he joined the group of Professor Rai-Shung Liu to pursue his PhD degree in National Tsing Hua University (Taiwan) and completed it in 2014. Subsequently, he worked as a postdoctoral fellow in the same group for one year. Currently, he is working as a Research Scientist at The Ohio State University, Columbus, Ohio USA. His research focused on the development of new organic reactions by using transition-metal catalysis such Gold, Silver, Rhodium, Zinc, Cobalt, Nickel and Copper metals which enables mild, diastereoselective, enantioselective and efficient transformations of variety of readily available substrates to wide range of synthetically useful nitrogen and oxygen containing heterocyclic products which are medicinally important. He published his research in a very high impact factor international Journals includes  J. Am. Chem. Soc.,  Angew. Chem. Int. Ed.,  J. Org. Chem.,  Chem- A. Eur. Journal,  Org. Biomol. Chem., and Synform (Literature Coverage).


Experience




Research experience

  • Sep 2015–
    Mar 2016
    Post doctoral Researcher
    The Ohio State University · Department of Chemistry and Biochemistry
    United States · Columbus
  • Aug 2014–
    Jul 2015
    Post Doctoral Researcher
    National Tsing Hua University · Department of Chemistry
    Taiwan
Intro

Dr. Vinayak Pagar
Postdoctoral Researcher
Department of Chemistry and Biochemistry
The Ohio State University
100 West 18th Avenue
Columbus, Ohio 43210 USA

Dr. Vinayak’s Profile

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/////////Vinayak Pagar, Postdoctoral Research Fellow, The Ohio State University,