DR ANTHONY MELVIN CRASTO,WorldDrugTracker, helping millions, A 90 % paralysed man in action for you, I am suffering from transverse mylitis and bound to a wheel chair,With death on the horizon, This will not stop me, Gods call only..........
DR ANTHONY MELVIN CRASTO Ph.D ( ICT, Mumbai) , INDIA 29Yrs Exp. in the feld of Organic Chemistry,Working for GLENMARK PHARMA at Navi Mumbai, INDIA. Serving chemists around the world. Helping them with websites on Chemistry.Million hits on google, world acclamation from industry, academia, drug authorities for websites, blogs and educational contributio

Monday, 7 December 2015

Shirin Amanpour

Shirin Amanpour

Shirin Amanpour

Reasearcher/ R&D at Pharmacutical Company


Tayebeh Amanpour

Tayebeh Amanpour/SHIRIN


An organic chemist with 8 years experience in synthesis, purification and characterization of materials and six months experience in microwave chemistry. Adept at laboratory management and working in teams and collaborations.


  • Sep 2015–present
    expert researcher
    R&D · Pharmacutical company
  • Jan 2014–Jun 2014
    Karl-Franzens-Universität Graz
  • Mar 2013–Mar 2015
    Iran Polymer and Petrochemical Institute
  • Sep 2003–Sep 2014
    PhD., M.Sc. , B.Sc.
    Shahid Beheshti University · Department of Chemistry · Dr. Ayoob Bazgir
    Iran · Tehrān


Reasearcher/ R&D

Pharmacutical Company
August 2015 – Present (5 months)Tehran/Iran

Reasearch assistant

Department of Polymer group Petrochemical Research Institute
September 2014 – August 2015 (1 year)Iran/ Tehran
Synthesis of different type of doner for Ziegler-Natta Catalyst

PHD. Organic Chemistry

Research assistant (M.Sc. and Ph.D. Student) Shahid Beheshti university, Tehran, Iran
October 2010 – September 2014 (4 years)Shahid Beheshti University
Thesis title: The Synthesis of new derivatives of benzopyranophenazine, ferrocenyltetrazole, benzodiazepine and furochromen via isocyanide based multi-component reaction.

Research assistant

Department of Customer-oriented research group Petrochemical Research Institute
February 2012 – December 2013 (1 year 11 months)Tehran/ Iran
esterification- synthesis of peroxides




An efficient, three-component synthesis of spiro[benzo[g]chromene-4,3'-indoline]-3-carbonitrile and spiro[indoline-3,5'-pyrano[2,3-d]pyrimidine]-6'-carbonitrile derivatives

J. Heterocyclic Chem

Clean Synthesis of Spiro[indole-3,8'-phenaleno[1,2-b]pyran]-9'-carbonitriles and Spiro[indole-3,4'-pyrano[4,3-b]pyran]-3'-carbonitriles by One-pot, Three-component Reactions

J. Heterocyclic Chem.

One –pot and three-component synthesis of spironaphthopyrano[2,3-d]pyrimidine-5,3'-indolines in water

J. Heterocyclic Chem.

Pseudo four-component synthesis of benzopyranopyrimidines


One-pot and three-component synthesis of spiro[chromeno[2,3-‎d]pyrimidine-5,3'-indoline]-diones and spiro[chromeno[2,3-c]pyrazole-4,3'-indoline]-diones

J. Heterocyclic Chem

A simple four-component synthesis of ferrocenyl amidodiesters and ferrocenyl triamides

Journal of Organometallic Chemistry

Isocyanide-Based Three-Component Synthesis of Pyrano-pyrido-quinoxalines

Helvetica Chimica Acta

Isocyanide-Based Five-Component Synthesis of 2-Aryl-2-(2,3,4,5-tetrahydro- 2,4-dioxo-1H-1,5-benzodiazepin-3-yl)acetamides (= α-Aryl-2,3,4,5- tetrahydro-2,4-dioxo-1H-1,5-benzodiazepine-3-acetamides)

Helvetica Chimica Acta

Isocyanide-based four-component synthesis of ferrocenyl1,5-disubstituted tetrazoles

Tetrahedron Letters

Isocyanide-Based Four-Component Synthesis of Benzo[a]pyrano[2,3-c]phenazines Four-Component Synthesis of Benzo[Tayae]pyrano[2,3b-c]phenazinees


Isocyanide-based four-component synthesis of 1,3-indandionylamidinium betaines


An efficient synthesis of furo[3,4-c]coumarins via the reaction of salicylaldehydes, β-ketoesters and isocyanides

Journal of the Iranian Chemical Society 2013

An Efficient Isocyanide-Based Three-Component Diastereoselective Synthesis of Chromane-3,4-dicarboxamides

Helvetica Chimica Acta

Atom-economical isocyanide-based multicomponent synthesis of 2,5-dioxopyrrolidines, spirobenzothiazinechromans and 1,5-benzothiazepines


Pseudo five-component synthesis of 5-phenyldihydrospiro[diindenopyridine-indenoquinoxaline]dione derivatives via a one-pot condensation reaction

Monatshefte für Chemie - Chemical Monthly


Shahid Beheshti University

Doctor of Philosophy (Ph.D.), Organic Chemistry
2010 – 2014

Shahid Beheshti University

Master of Science (MSc), Organic Chemistry
2007 – 2009

Shahid Beheshti University

Bachelor of Science (B.Sc.), Pure Chemistry
2003 – 2007


Jasmine, Dr Reddy's Laboratories Ltd


Jasmine , ASQ CQE, CPGP

Quality by Design at Dr. Reddy's Laboratories

  Image result for qbd


Chemical Engineer, ASQ Certified Quality Engineer and ASQ Certified Pharmaceutical GMP Professional.

Significant experience in Pharmaceutical manufacturing sites - Drug Substance Scale-up and Technology Transfer, Manufacturing, Quality Management Systems, Lifecycle Implementation of Quality. 
Designing Quality into Product Development of Complex Generic Drug Substances & Drug Products currently.

Experience in Continuous Coated Paper and Semi-batch Dye & Pigment Manufacturing. 

ASQ Country Counsellor - Switzerland

Key Skills: QbD implementation, Chemical Engineering, cGMP, QMS, Robust Process & Product Design, CMC, Six Sigma, Design of Experiments, Statistical Process Control, Continuous Process Verification, Risk Management, Technical Training.

Improving the Quality of life for customers and in turn businesses, one day at a time.
Jasmine Image

Image result for qbd


She has  recently started writing in a wonderful Pharmaceutical Magazine called the Medicine Maker. Also I would suggest you to subscribe to and also read the magazine (it is free), it is a very informative, very well articulated magazine.


Panjab University

Bachelor of Engineering (B.E.), chemical engineering
2002 – 2006
Activities and Societies: Member, Student Chapter of IIChE

St.Annes Convent School

High School
1999 – 2000


Principal Scientist- Quality by Design

Dr. Reddy's Laboratories
 – Present (11 months)Basel Area, Switzerland
Developing diverse complex generic products- right first time. Use of Six Sigma and other Quality Management principles to optimize product development. Ensure life cycle assurance of product quality.

Image result for dr reddys

Senior Scientist- Quality by Design

Dr. Reddy's Laboratories
February 2014 – Present (1 year 11 months)Hyderabad Area, India
Lead the Quality by Design facilitation team for Oral Solid Dosage Development team including Pharmaceutical, Analytical, Packaging, Bio scientists.
• Create best practices of QbD/ DFSS based development and champion the use of QbD tools like Design of Experiments (DoE), Monte Carlo Simulations (MCS), Artificial Neural networks (ANN), Multivariate Analysis (MVA) and other statistical tools, systematic Risk Assessment tools including FMECA.
• Develop a QbD based Process Validation strategy for Drug Formulations.
• A part of the organization- wide QbD initiative to facilitate QbD across the product lifecycle in Drug Substance and Drug Product Development & Manufacturing.

Manager- Technology Transfer

July 2007 – January 2014 (6 years 7 months)Gurgaon
Process Engineering, Scale-Up, Cost Reduction, Process Intensification:
Responsible for managing the scale-up of chemical processes for generic Active Pharmaceutical Ingredients from the R&D's Laboratory scale to the Manufacturing Plant scale through Kilogram Laboratories and Pilot Plants to deliver robust and safe chemical processes for scale-up, technology transfer and commercial manufacturing.
Quality by Design Implementation:
Bridging the gap leading to a QbD way of working for Ranbaxy. Well versed in Chemometrics including Statistical Quality Control tools and Design of Experiments (DoE) and Multivariate Analysis (MVA) with hands-on PAT experience with tools like FBRM, PVM, IR etc.Risk Management Principles and tools like FMECA, HAZOP,etc. for Process and Safety Risk Assessment. Designing the New Process Validation Guideline including Lifecycle Implementation of Quality.
Internal Trainer in QbD, PAT and SPC. Participated in QbD seminars and conferences as a Speaker.
Implementation of Statistical Process Control:
Spearhead the Design and Implementation process of Statistical Process Control for various sites across Ranbaxy.

Graduate Engineer Trainee- Process

Ballarpur Industries Limited
July 2006 – July 2007 (1 year 1 month)Bhigwan, Maharashtra
Employed in Ballarpur Industries Limited (BILT)Unit Bhigwan, Maharashtra: a state of the art Coated Paper Manufacturing Plant in two profiles:
PRODUCTION: Managed the Off-Machine Coater and responsible for production, maintenance and quality. I managed up to twenty people in my shift directly apart from organizing and coordinating with allied departments. The 1500m/min speed Jagenberg coater capable of manufacturing Art and Chromo papers ranging from 70 to 350 gsm offered me the experience of working with Industrial Control Systems like SCADA, DCS and PLCs. Also involved in Process Intensification, TPM, TQM, 5S and 6 sigma projects.
A part of the Project Team for a brown field project including an online coating machine from Voith Paper, Germany. The $200 million project taught me immensely about Project Engineering and Management. Working on the project with international organizations like Voith, Metso, Jagenberg etc. gave me global exposure to the Paper Industry.

Summer Intern

Sudarshan Chemical Industries Ltd.
May 2005 – June 2005 (2 months)Pune, Roha, Mahad
Environmental Management & Design of Effluent Treatment Facilities in a Dye and Pigment Industry


Certified Quality Engineer

ASQ, License 61328
June 2013 – June 2016

Certified Pharmaceutical GMP Professional

ASQ, License 420
December 2014 – December 2017


American Society for Quality ASQ

Starting January 2013

Indian Institute of Chemical Engineers IIChE

Starting December 2007


Dr. Reddy's Laboratories

  • Level A1 German, Goethe Zentrum, Hyderabad

Volunteer Experience & Causes

Volunteer- API Process Technology


With Jasmine , ASQ CQE, CPGP
Quality by Design , PARINCIPAL SCIENTIST at Dr. Reddy's Laboratories, At ACS 2016
 — at Dr. Reddys Laboratories , Leadership Academy, Bachupally, Hyderabad.

August 2012Science and Technology

KNOW Your Speaker - Ms. Jasmine, Senior Scientist, Dr Reddy's Laboratories will deliver a talk on 'Statistics in Product Development- Beyond #DoE' @ QbD in Pharma Development World Congress 2015 #QBDINDIA2015 bit.ly/1wkjvWj scheduled to be held on April 16-18, 2015
looking for motivation with Pooja Sharma, Tejinder Singh, Shreya Feliz and 16 others at Select Biosciences India.

 Jasmine , ASQ CQE, CPGP


Image result for qbd

Image result for dr reddys
Late  K Anji Reddy, the founder and exChairman of nation's second-largest drugmaker Dr Reddy's Laboratories Ltd,
  • Satish ReddySatish Reddy
  • G V PrasadG V Prasad


//////////Jasmine, Scientist, Dr Reddy's Laboratories, QBD, 

Igor Plazl, Professor, University of Ljublja

Igor Plazl Image

Igor Plazl

Professor of Chemical Engineering at University of Ljubljana
Aškerčeva cesta 5
1000 Ljubljana Slovenia
Telephone:+386 1 2419 100 Fax: +386 1 2419 220
 e-mail: igor.plazl@fkkt.uni-lj.si
Dr. Igor Plazl graduated from chemical engineering at the Faculty of Chemistry and Chemical Technology, University of Ljubljana, in 1978.
He was awarded his PhD in 1993 and became a full professor of chemical engineering in 2010.
He has published reviewed university textbook entitled Introduction to Process Modeling, 2004.
In 1989, he worked in Bayer AG, Leverkusen, and in 2003/04 half-year at Oregon State University, USA as a visiting professor (Fulbright Grant).
He was Vice dean of the Faculty of Chemistry and Chemical Technology, University of Ljubljana in 2010-2014.
His main research interests are applications of microwaves in chemical industry, mathematical modeling of (bio)chemical processes, and microreactor technology. He had many invited and also plenary lectures and he has published several cited papers in peer reviewed journals on the topic of microfluidics.
He is the co-editor of Chemical and Biochemical Engineering Journal, a member of Working Party on Process Intensification and CAPE-WP (EFCE), COST Action MP1305 Flowing matter, and Slovenian Chemical Society.




Full Professor

University of Ljubljana, Faculty of Chemistry and Chemical Technology
September 1990 – Present (25 years 4 months)Askerceva 5, 1000 Ljubljana



Coordinator: Technical University of Denmark - Department of Chemical and Biochemical Engineering (Krist Gernaey, Ulrich Kruhne)


Continuous steroid biotransformations in microchannel reactors(Link)

New Biotechnology, 29, 227–234
January 15, 2012

Map of university of ljubljana


With Igor Plazl at Crater Lake National Park.


 Map of ljubljana