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Thursday, 19 May 2016

Liron Oskar

Liron Oskar

Liron Oskar

Research and Development Chemist at Taro Pharmaceutical Industries



Research and Development Organic Chemist

Taro Pharmaceutical Industries
 – Present (1 year 5 months)Haifa, Israel

Laboratory Teaching Assistant

Technion - Israel Institute of Technology
 –  (1 year 11 months)


Technion - Israel Institute of Technology

Bachelor's degree, Chemistry



M.Sc Thesis

M.Sc StudentLiron Oskar
SubjectMerging Allylic Carbon-Hydrogen and Carbon-Carbon Bond
Activations en-route to Sophisticated
Molecular Framework
DepartmentDepartment of Chemistry
SupervisorFull Professors Marek Ilan
Full Thesis textFull thesis text - English Version


Recently, our group has developed the zirconocene-mediated ring opening of alkylidenecyclopropanes (ACPs) and w-ene cyclopropanes derivatives, via a unique and selective merging of allylic carbon-hydrogen and carbon-carbon bond activations, leading to bismetallated zirconocene complex. The addition of two different electrophiles gives bisfunctionalized acyclic molecules in excellent yields. By diversifying the nature of the two electrophiles, two stereogenic centers were created with high diastereoselectivity.
In this context, we proposed to enlarge the scope of this process by creating three stereogenic centers in an acyclic product via a one-pot sequence, while studying the diastereoselectivity.
Since zirconocene-mediated ring opening was done with stoichiometric amount of zirconocene complex, we tried to develop a catalytic process for the ring cleavage applied on ACPs derivatives, based on the successful catalytic carbozirconation on multiple bonds.
A deeper mechanistic understanding of the combined allylic carbon-hydrogen and carbon-carbon bond activations pathway was also proposed, using labeled experiments.
Finally, we applied our zirconocene-mediated ring opening methodology to the synthesis of the two enantiomers of deuterated neopentane: the smallest enantiomerically enriched hydrocarbons that possess an all-carbon quaternary stereocenter, that is, a carbon center with four different non-hydrogen substituents. Using advanced and sensitive methods, we successfully determined their absolute configuration.



Jigisha Varia

Jigisha Varia RAC (US).

Jigisha Varia RAC (US)

Associate Director Regulatory Affairs at eVenus Pharmaceutical Laboratories, Inc.




Associate Director Regulatory Affairs

eVenus Pharmaceutical Laboratories Inc.
– Present (4 months)Greater New York City Area

Senior Manager Regulatory Affairs

eVenus Pharmaceutical Laboratories, Inc.
(9 months)Greater New York City Area

Manager Regulatory Affairs

(1 year 10 months)Greater New York City Area

Senior Associate, Regulatory affairs

(2 years 1 month)greater detroit area

Senior Regulatory affairs/Product development

Revogenex Inc
(2 years 5 months)

Senior Research scientist

(4 years 2 months)

Research associate

(7 months)


The Maharaja Sayajirao University of Baroda

Maters in pharmaceutical technology, pharmaceutics


Renana Poranne

Renana Poranne

Renana Poranne

PostDoc Researcher - ETH Zurich
  • Department of Chemistry and Applied Biosciences
    Zürich, ZH, Switzerland


Postdoctoral Researcher

ETH Zurich
– Present (9 months)Zürich Area, Switzerland


Technion - Israel Institute of Technology

Bachelor of Science (BSc), Molecular Biochemistry, 96.6

Activities and Societies: Student Body Representative
Technion PhD student Renana Gershoni Poranne soaks in the magic of Mainau Island on a lunch break from scientific mingling

Research experience

  • Sep 2015–present
    PostDoc Position
    ETH Zurich · Department of Chemistry and Applied Biosciences · Chen
    Switzerland · Zürich, Zurich
  • Apr 2010–Jul 2015
    PhD Student
    Technion - Israel Institute of Technology · Schulich Faculty of Chemistry · Stanger
    Israel · Haifa
  • Sep 2007–Apr 2010
    Master's Student
    Technion - Israel Institute of Technology · Faculty of Chemistry · Keinan
    Israel · Haifa, Haifa

/////Renana Poranne