DR ANTHONY MELVIN CRASTO,WorldDrugTracker, helping millions, A 90 % paralysed man in action for you, I am suffering from transverse mylitis and bound to a wheel chair,With death on the horizon, This will not stop me, Gods call only..........
DR ANTHONY MELVIN CRASTO Ph.D ( ICT, Mumbai) , INDIA 29Yrs Exp. in the feld of Organic Chemistry,Working for GLENMARK PHARMA at Navi Mumbai, INDIA. Serving chemists around the world. Helping them with websites on Chemistry.Million hits on google, world acclamation from industry, academia, drug authorities for websites, blogs and educational contributio

Tuesday, 17 May 2016

Jenna Jeffrey

Jenna Jeffrey

Jenna Jeffrey was born in Springfield, OR. Although she didn�t exactly grow up on Evergreen Terrace, she still lived pretty close to the Simpson family. When she moved around the world she was devastated at the thought of losing friendships with Bart and Lisa, then she realized that she took the long way to move to Eugene and that Springfield was just across the river. She really didn�t want to take another chance at losing the Simpsons forever, so she stayed in Eugene for college at the University of Oregon, where her diet consisted mainly of pizza, ice cream, pizza flavored ice cream (but NOT ice cream flavored pizza) and the occasional Squishy from the local Kwik-E-Mart. Although that all sounds fattening, Jenna worked off all the calories with her favorite hobbies, running and soccer (aka running with somewhat of a purpose). While at Oregon, Jenna worked with Mike Haley, who looks an awful lot like a relative of the groundskeeper from her elementary school days. Jenna, however, has one regret from her youth. She was never able to learn to skateboard, even from the greatest of teachers, Bart.

Contact Information

Email: jennajeffrey at calmail dot berkeley dot edu 

Jenna Jeffrey
B.S. University of Oregon
Ph.D. University of California, Berkeley
Currently: Post-doc withProf. David MacMillan
Joined in: 2008

Research Interests

The synthesis of complex molecules, such as pharmaceuticals, relies on the development of efficient, scalable and operationally simple chemical transformations. Reactions that directly transform a C–H group into another functional group are particularly valuable tools for streamlining synthesis. My research is focused on the development of new methods and strategies for the synthesis of organic molecules. Two specific areas of current interest are (i) intramolecular carbon–nitrogen bond formation and (ii) carbon–carbon bond forming processes, which rely on the merger of organocatalysis and visible-light mediated photoredox catalysis.

Contact Info

NIH Postdoctoral Fellow
MacMillan Group
Department of Chemistry
Princeton University
Princeton, NJ 08544

Mobile: (541) 337-2755
Email: jjeffrey@princeton.edu


8. Jeffrey, J. L.; Terrett, J.; MacMillan, D.W.C., “O–H Hydrogen bonding promotes H-atom transfer from α C–H bonds for C-alkylation of alcohols,” Science 2015, 349, 1532–1536. (link)

7. Jeffrey, J. L.; Petronijevic, F. R.; MacMillan, D.W.C., “Selective Radical–Radical Cross-Couplings: Design of a Formal β-Mannich Reaction,” J. Am. Chem. Soc. 2015, 137, 8404–8407. (link)

6. Jeffrey, J. L.; Sarpong, R. “ Intramolecular C(sp)3–H amination,” Chem. Sci. 2013, 4, 4092–4106. (link)

5. Jeffrey, J. L.; Bartlett, E. S.; Sarpong, R. “Intramolecular C(sp)3–N Coupling by Oxidation of Benzylic C,N-Dianions,” Angew. Chem. Int. Ed. 2013, 52, 2194–2197. (link

         •  Featured in Synfacts, 9, 0533 (link).

4. Jeffrey, J. L.; Sarpong, R. “Chichibabin-Type Direct Alkylation of Pyridyl Alcohols with Alkyl Lithium Reagents,” Org. Lett. 2012, 14, 5400–5403. (link)

•  Featured in Synfacts, 9, 0194 (link).

3. Jeffrey, J. L.; Sarpong, R. “Concise Synthesis of Pauciflorol F Using a Larock Annulation,” Org. Lett. 2009, 11, 5450–5453. (link)
2. Jeffrey, J. L.; Sarpong, R. “An approach to the synthesis of dimeric resveratrol natural products via a palladium-catalyzed domino reaction,” Tetrahedron Lett. 2009, 50, 1969–1972. (link)
1. Jeffrey, J. L.McClintock, S. P.; Haley, M. M. “Synthesis of 1-substituted benzo[c]isoxazol-3(1H)-imines via tandem nitroso-ene/intramolecular cyclizations of 2-nitrosobenzonitrile,” J. Org. Chem. 2008, 73, 3288–3291. (link)



Rebecca Murphy


Rebecca Murphy 

Hailing from the great state of Massachusetts, Rebecca grew up in the rural town of Chelmsford. As a youngster, Rebecca picked up the art of horseback riding, and realized she wanted to be a world-class equestrian rider. After much training in Chelmsford and her parent's farm in Rhode Island, Rebecca's opportunity came at the University of Rochester where she not only was part of the Equestrian Club (proudly competing in Zone 2, Region 2 of the IHSA), she also picked up a B.S. in chemistry researching under the tutelage of Dr. Robert K. Boeckman, Jr. in the area of organic methodology. Realizing that the two and a half year gap of competing in the 2012 Olympics was out of reach, Rebecca galloped to UC Berkeley to begin her work in natural product synthesis. When Rebecca is not riding around campus, Rebecca enjoys a good movie (i.e. Dr. Zhivago), traveling around the world, or enjoying sushi and Indian cuisine (not mutually exclusive of course). 

Contact Information 

Email: rmurphy @calmail.berkeley.edu 

Rebecca Murphy
B.S. University of Rochester
Ph.D.: University of California, Berkeley
Currently: Pfizer
Joined in: 2009

Rebecca Murphy

Undergraduate: University of Rochester (Rochester, NY)
Group at Berkeley: Professor Richmond Sarpong, joined 2009
Research Interests: Natural product synthesis
ISP Initiation: 2009
ISP Position(s): President (2011-2012)
Other Interests: Rebecca enjoys distance running and horseback riding in her free time.
Select Publications:
Murphy, R. A.; Sarpong, R. Direct Methoxypyridine Functionalization Approach to Magellanine-Type Lycopodium Alkaloids. Org Lett. 2011.



Michal Shavit

Michal Shavit.

Michal Shavit

Research Scientist at On Target Chemistry Israel

On Target Chemistry official opening


Research Scientist

On Target Chemistry from the Recipharm group
 – Present (8 months)Ness Ziona, Israel

Postdoctoral Researcher

Technion - Israel Institute of Technology
 –  (8 months)Haifa

Research Assistant

Columbia University
 –  (1 year 1 month)


Technion - Israel Institute of Technology

Doctor of Philosophy (PhD), Chemistry

The Hebrew University

Master of Science (MSc), Chmistry

The Hebrew University of Jerusalem

Bachelor’s Degree, Chmistry


Active cytotoxic reagents based on non-metallocene non-diketonato well-defined C2-symmetrical titanium complexes of tetradentate bis(phenolato) ligands(Link)

J. Am. Chem. Soc.
September 18, 2007
A new family of non-Cp-based non-diketonato-based C2-symmetrical octahedral Ti(IV) complexes of dianionic diamine bis(phenolato) ligands, which are conveniently obtained as single isomers in quantitative yields, leads to appreciable cytotoxicity against colon and ovarian cells with a non-transferrin-dependent cell penetration mechanism. The ligand structural features including steric demands,...more

Structural characterization of dinuclear Ti(IV) complexes of rigid tetradentate dianionic diamine bis(phenolato) ligands; effect of steric bulk on coordination features(Link)

Journal of Organometallic Chemistry
October 4, 2008
A small difference in diamine bis(phenolato) ligands, namely an additional single methylene unit, directs formation of dinuclear Ti(IV) complexes rather than mononuclear ones as characterized by X-ray crystallography. Varying steric bulk of the ligand affects the coordination number in the dinuclear complexes and the ligand to metal ratio. A ligand with reduced steric bulk leads to a L2Ti2(OiPr)4...more

Antitumor Reactivity of Non-Metallocene Titanium Complexes of Oxygen-Based Ligands: is Ligand Lability Essential?(Link)

J. Biol. Inorg. Chem.
July 2007
In our attempt to define the parameters affecting anticancer activity of titanium complexes and to assess the role of hydrolytic stability, titanium compounds of oxygen-based ligands were studied. A homoleptic complex of hydroxyamino-1,3,5-triazine ligands was prepared and its hydrolysis was investigated by UV–vis spectroscopy at biologically relevant pH and temperature conditions based on its...more
4 authors
  • Michal Shavit
    Michal Shavit
    Research Scientist at On Target Chemistry Israel
  • Dani Peri
    Dani Peri
    Materials and Inorganic Chemist
  • No photo
    Artem Melman
  • No photo
    Edit Y. Tshuva

Preparation and X-Ray Structures of Ti(IV) Complexes of Bis(carboxylato) Ligands; Formation of Mono-, Di-, Tetra- and Hexanuclear Complexes With or Without OR and μ-O Ligands

Eur. J. Inorg. Chem.
2 authors

Synthesis, Characterization, Cytotoxicity, and Hydrolytic Behavior of C2 and C1-Symmetrical Ti(IV) Complexes of Tetradentate Diamine Bis(Phenolato) Ligands: A New Class of Antitumor Agents

Chem. Eur. J

TiIV Complexes of Branched Diamine Bis(phenolato) Ligands: Hydrolysis and Cytotoxicity

Eur. J. Inorg. Chem.

Increased Selectivity toward Cytoplasmic versus Mitochondrial Ribosome Confers Improved Efficiency of Synthetic Aminoglycosides in Fixing Damaged Genes: A Strategy for Treatment of Genetic Diseases Caused by Nonsense Mutations

Journal of Medicinal Chemistry

Design of Novel Aminoglycoside Derivatives with Enhanced Suppression of Diseases-Causing Nonsense Mutations

ACS Medicinal Chemistry Letters
February 8, 2016