Dr. Vandana Arora Sethi
Head of the Department at School of Pharmacy, Lloyd Institute of Management & Technology
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Experience
Education
Delhi University
M.Pharm., Pharmaceutics, First- Gold medalist
Activities and Societies: Debates and Anchoring -
Honors & Awards
LG Trophy for the Best Outgoing student
Delhi Government
Sai Medha Award for the best student
Best Teacher Award
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Cite this article as:Vandana Arora Sethi, Abdul W. Siddiqui, Govind Mohan, Development and Evaluation of Niosomal Formulation of Famciclovir, Asian Journal of Pharmaceutical Technology & Innovation, 03 (13); 2015. www.asianpharmtech.com
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Development and Evaluation of Niosomal Formulation of Famciclovir
Vandana Arora Sethi*1, Abdul W. Siddiqui2, Govind Mohan31,3 Department of Pharmacy, NIMS University, Jaipur Rajasthan
2 Department of Pharmacy, Mangalayatan University, Aligarh U.P.________________________________________________________________________________________________________________ABSTRACT
Niosomes are one of the best and most effective among these carriers system. Because of the presence of hydrophilic, lipophilic and amphiphilic moieties in the structure, these niosomes can accommodate various drug molecules with a wide range of solubility. So, these may act as a depot, releasing the drug in a defined manner. Rationale behind the present study is to improve the oral bioavailability of Famciclovir by preparing niosomes. Encapsulation of Famciclovir in lipophilic vesicular structure may be expected to enhance the dissolution, oral absorption and prolong the existence of the drug in the systemic circulation. The niosomal dispersions were formulated using various combinations of cholesterol and spans. The formulations were evaluated in-vitro and in-vivo and compared with the marketed preparation of Famciclovir.Key-words: liposomes, niosomal dispersion, famciclovir, in vivo study.______________________________________________________________________________________________________________________________________________________Corresponding Author: * Vandana Arora Sethi, Department of Pharmacy, NIMS University, Jaipur, Rajasthan, India. Mob.no. +919873250790 -
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