DR ANTHONY MELVIN CRASTO,WorldDrugTracker, helping millions, A 90 % paralysed man in action for you, I am suffering from transverse mylitis and bound to a wheel chair,With death on the horizon, This will not stop me, Gods call only..........
DR ANTHONY MELVIN CRASTO Ph.D ( ICT, Mumbai) , INDIA 29Yrs Exp. in the feld of Organic Chemistry,Working for GLENMARK PHARMA at Navi Mumbai, INDIA. Serving chemists around the world. Helping them with websites on Chemistry.Million hits on google, world acclamation from industry, academia, drug authorities for websites, blogs and educational contributio
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Sunday, 4 January 2015

Dr John Tsanaktsidis



Dr John Tsanaktsidis


Dr John Tsanaktsidis,  CSIRO Materials Science and Engineering.

Dr Tsanaktsidis is a Chief Research Consultant at CSIRO (Manufacturing Flagship) with experience in developing and delivering scientific outcomes to industry, with demonstrated achievements in scientific research and management, technology commercialisation, and business leadership.

 

 

Specialties: Flow Chemistry, Process Development, RAFT Agent Manufacture, Polymer-Drug conjugates, Fine Chemicals from Biomass, Cubane Chemistry, Technology Commercialization; Business Leadership

He was recognized in 2006 through a Distinguished Alumni Award from The Flinders University of South Australia, and in 2012 through a Chief’s Innovation Award from CMSE.

Qualifications:
  • BSc (Hons)
  • PhD
Expertise:
Synthetic organic chemistry
Current project:
Developing new chemical processes through continuous flow processing

 Australian Innovation Showcase India 2013 Dr John Tsanaktsidis, CSIRO

 

 

 

Current activities

Dr Tsanaktsidis is a synthetic organic chemist currently focussed on:
  • continuous flow processing methods to chemical synthesis and its application to process development for industrial applications
  • RAFT polymerisation technology to drug delivery and bioactive molecule discovery
  • the conversion of renewable biomass feedstocks into fine chemicals and fuels.
Dr Tsanaktsidis believes that Flow Chemistry will be a revolution in fine chemical processing.
 

Dr Tsanaktsidis led the establishment of the Flow Chemistry Laboratory at CSIRO. This Laboratory houses a world-class capability in continuous flow processing, and represents a significant and growing capital investment by CSIRO.
This laboratory is unique in Australia and world competitive complementing CSIRO’s strengths in batch mode chemical synthesis at laboratory and pilot scale.
This new capability represents a fresh paradigm in chemical manufacturing and is being deployed in a number of commercially oriented projects, including polymer synthesis, pharmaceutical production, and conversion of renewable feed stocks into platform fine chemicals and biofuels.
Dr Tsanaktsidis believes that Flow Chemistry will be a revolution in fine chemical processing and will change the way that industrial chemicals and pharmaceuticals are manufactured in the future.
He is keen to ensure that CSIRO’s knowhow is being used to develop innovative and more competitive processes to support a new era of innovative chemical manufacturing in Australia.

Background

Dr Tsanaktsidis has undertaken an array of roles ranging from independent scientific research at the School of Chemistry, The University of Melbourne, to client funded R&D projects, business development and commercialisation, and senior management at CSIRO.
From 2005 to 2007 Dr Tsanaktsidis served as Managing Director of Boron Molecular Pty. Ltd.
He has worked with a number of multinational companies and small to medium sized enterprises on the development and commercialisation of various technologies.

Education and training

Dr Tsanaktsidis completed his Bachelor of Science (Chemistry – Honours First Class) and Doctor of Philosophy (Chemsitry) at Flinders University in South Australia.
He undertook postdoctoral studies first at the University of Chicago, USA as a Postdoctoral Research Associate in the Department of Chemistry; then as a Postdoctoral Research Fellow at the Research School of Chemistry at the Australian National University (ANU).
Further studies included:
  • Gustav Kaser Training – Management One
  • Company Directors Course Diploma, Australian Institute of Company Directors
  • Graduate Certificate in Management (Technology Management), APESMA-Deakin University.


FLINDERS  UNIV

 

Awards and affiliations

Dr Tsanaktsidis has been recognised by CSIRO Project Management and Business Excellence; and in 2006 his career achievements were recognized by Flinders University of South Australia through a Distinguished Alumni Award:
John Tsanaktsidis is Managing Director of Boron Molecular Pty Ltd and it is the exception rather than the rule that chemists rise to become Chief Executives of companies. He is one of the world’s foremost experts on the chemistry of cubanes, and his Award acknowledges that, as well as, his development of a new method for preparing methoxyflurane used for delivering analgesics to trauma victims, and business leadership.
Dr Tsanaktsidis has achieved the following awards and affiliations:
  • Graduate, Australian Institute of Company Directors (GAICD), 2007
  • Distinguished Alumni Award, Flinders University, 2006
  • CSIRO Award for Project Management, 2004
  • CSIRO Award for Business Excellence, 2003
  • Fellow of the Royal Australian Chemical Institute (FRACI), 2000
  • Flinders University Overseas Travelling Award, 1986.

Publishing History


Hutt OE, Freemont JA, Littler S, Duggan PJ, Tsanaktsidis J, Ryan, JH. 2012. Staudinger and Ruzicka’s Altered Pyrethrolone: The Cyclopentadienone Dimers Derived from Pyrethrin I. Horta Acta. Accepted.
Churches QI, Mulder RJ, White LM, Tsanaktsidis J,  Duggan PJ. 2012. The Synthesis of a Cubane-Substituted Dipeptide. Australian Journal of Chemistry. 65: 690–693.
Ko EJ,  Williams CM, Savage GP, Tsanaktsidis J. 2012. Reductive Radical Decarboxylation of Aliphatic Carboxylic Acids. Organic Syntheses. 89: 471-479.
Moad G, Bicciocchi E, Chen M, Chiefari J, Guerrero-Sanchez C, Haeussler M, Houshyar S, Keddie D, Rizzardo E, Thang S, Tsanaktsidis J. 2012. Some Recent Developments in RAFT Polymerization. Progress in Controlled Radical Polymerization: Mechanisms and Techniques. ACS Symposium Series 2012. Chapter 16, pp 243–258.
Houshyar S, Keddie D, Moad G, Mulder R, Saubern S, Tsanaktsidis J. 2012. The Scope for Synthesis of Macro-RAFT Agents by Sequential Insertion of Single Monomer Units. Polymer Chemistry. 3: 1879-1889.
Williams CW, Thang SH, Hantke T, Vogel U, Seeberger PH, Tsanaktsidis J, Lepenies B. 2012. RAFT-derived polymer-drug conjugates: poly(hydroxypropyl methacrylamide)-SN-38 conjugates. ChemMedChem. 7: 281 – 291.
Brasholz M, Von Kaenel K, Hornung CH, Saubern S, Tsanaktsidis J. 2011. Highly efficient dehydration of carbohydrates to 5-(chloromethyl)furfural (CMF), 5-(hydroxymethyl)furfural (HMF) and levulinic acid by biphasic continuous flow processing. Green Chemistry. 13: 1114-1117.
Ko EJ, Savage GP, Williams CW, Tsanaktsidis J. 2011. Reducing the cost, smell and toxicity of the Barton reductive decarboxylation: Chloroform as the hydrogen atom source. Organic Letters. 13 (8): 1944–1947.
Griffiths RG, Tsanaktsidis J, Savage GP, Priefer R. 2010. Thermochemical properties of iodinated cubane derivatives. Thermochimica Acta. 499 (1-2): 15-20.
Brasholz M, Johnson BA, Macdonald JM, Polyzos A, Tsanaktsidis J, Saubern S, Holmes AB, Ryan JH. 2010. Flow Synthesis of Tricyclic Spiropiperidines as Building Blocks for the Histrionicotoxin Family of Alkaloids. Tetrahedron. 66: 6445.
Tsanaktsidis J, Tiekink ERT. 2001. Crystal Structure of 1-Amino-2-thionebenzothiazole, C7H6N2S2. Zeitschrift für Kristallographie - New Crystal Structures. 216: 443.
Lock JS, May BL, Clements P, Tsanaktsidis J, Easton CJ, Lincoln SF. 2001. Size Discrimination in Intramolecular Complexation of Modified Cyclodextrins: A Preparative and Nuclear Magnetic Resonance Study. Journal of Chemical Society Perkin Transactions 1. 3361.
Maxwell BJ, Smith BJ, Tsanaktsidis J. 2000.  The Cyclization of N-Butyl-4-pentenylaminyl Revisited: A combined Theoretical and Experimental Study. Journal of Chemical Society Perkin Transactions 2. 425.
May BL, Clements P, Tsanaktsidis J, Easton CJ, Lincoln SF. 2000. Square Pegs in Round Holes. Preparation and Intramolecular Complexation of Cubyl Substituted a-Cyclodextrins and of an Adamantane Analogue. Journal of Chemical Society Perkin Transactions 1. 463.
Field MJ, May BL, Clements P, Tsanaktsidis J, Easton CJ, Lincoln SF. 2000. Intramolecular Complexation in Modified b-Cyclodextrins: A Preparative, Nuclear Magnetic Resonance and pH Titration Study. Journal of Chemical Society Perkin Transactions 1. 1251.
Cundy D, Gurr PA, Knill AM, Tsanaktsidis J. 2000. An improved synthesis of (S)-1-[[4-(dimethylamino)-3-methylphenyl]methyl]-5-(diphenylacetyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid ditrifluoroacetate dihydrate (PD123319). Arkivoc. 1: 158-164.
Maxwell BJ, Tsanaktsidis J. 1998. Book Chapter: Homolytic Addition Reactions of Dialkylaminyl Radicals. N-Centered Radicals, Z. B. Alfassi, Ed., pp 663-683, John Wiley & Sons, London.
Gable RW, Lowe DA, Tsanaktsidis J. 1998. endo-2,4-Dibromodicyclopentadiene-1,8-dione 8-Ethylene Ketal. Acta Crystallographica Section C.  151.
Bliese M, Fanning LA, Gable RW, Lowe DA, Tsanaktsidis J. 1998. Indirect Monobromination of the Cubane Nucleus. The Synthesis of Dimethyl 2-Bromocubane-1,4-dicarboxylate. Australian Journal of Chemistry. 51: 593.

 
Tsanaktsidis J. 1997. Book Chapter: Polysubstituted Cubanes: Towards Complete Systematic Substsitution of the Cubane Nucleus. Advances in Strain in Organic Chemistry, B. Halton, Ed. JAI Press Ltd., London, Volume 6, pp 67.
Bliese M, Tsanaktsidis J. 1997. Dimethyl 1,4-Cubanedicarboxylate: A Practical Laboratory Scale Synthesis. Australian Journal of Chemistry. 50: 189.
Smith B, Tsanaktsidis J. 1997. Cubyl Carbinyl Cation: Fact or Fiction? Journal of Organic Chemistry. 62: 5709.
Bliese M, Cristiano D, Tsanaktsidis J. 1997. Preparation of Dimethyl 2,3-Dimethyl-1,4-cubanedicarboxylate. Australian Journal of Chemistry. 50: 1043.
Bagnell L, Bliese M, Cablewski T, Strauss CS, Tsanaktsidis J. 1997. Organic Synthesis using High Temperature Aqueous Media: Preparation of 3-Methyl-2-cyclopentenone. Australian Journal of Chemistry. 50: 921.

 
Gable RW, Lowe DA, Tsanaktsidis J. 1997. endo-1,4,4-Tribromo-3-methyltricyclo[5.2.1.02,6]dec-8-ene-5,10-dione 10-Ethylene  Ketal. Acta Crystallographica Section C.  1916.
Maxwell BJ, Tsanaktsidis J. 1996. Cyclization of N-Butyl-4-pentenylaminyl: Implications for the Cyclization of Alkenylaminyl Radicals. Journal of the American Chemical Society. 118: 4276.
Cristiano D, Gable RW, Lowe DA, Tsanaktsidis J. 1995. Dimethyl 2-Methylcubane-1,4-Dicarboxylate and Dimethyl 2,3-Dimethylcubane-1,4-dicarboxylate. Acta Crystallographica Section C.  1658.
Eaton PE, Nordari N, Tsanaktsidis J, Upadhyaya SP. 1995. Barton Decarboxylation of Cubane-1,4-diacid: Optimised Procedures for Cubanecarboxylic Acid and Cubane. Synthesis. 501.
Maxwell BJ, Tsanaktsidis J. 1994. Influence of Bis(tributyltin) Oxide on Aminyl Radical Cyclizations. Journal of the Chemical Society, Chemical Communications.533.
Gable RW, Parker KJ, Tsanaktsidis J. 1994. Selective Bromochlorination of endo-1,4-Dibromotricyclo[5.2.1.02,6]deca-3,8-diene-5,10-dione 10-Ethylene Acetal at the Conjugated Carbon-Carbon Double Bond. Australian Journal of Chemistry. 47: 963.
Burnes P, Cristiano D, Glover MR, Tsanaktsidis J. 1994. A Convenient, Regiospecific Synthesis of Dimethyl 4-Oxocyclopentane-1,3-dicarboxylate. Australian Journal of Chemistry. 47: 1811.
Lowe DA, Moorhouse CJ, Walter JM, Tsanaktsidis J. 1994. A New Approach to Alkylated Cubanes: The Synthesis of Dimethyl 2-Methylcubane-1,4-dicarboxylateAustralian. Journal of Chemistry. 47: 1647.
Maxwell BJ, Schiesser CH, Smart BA, Tsanaktsidis J. 1994. Ab initio Study of the Homolytic Additions of Aminyl and Ammoniumyl Cation Radicals to Alkenes. Journal of Chemical Society Perkin Transactions 2. 2385.
Beckwith ALJ, Maxwell BJ, Tsanaktsidis J. 1991. The Generation of Aminyl Radicals from Sulfenamides. Australian Journal of Chemistry. 44: 1809.
Eaton PE, Tsanaktsidis J. 1990. The Reactions of 1,4-Dihalocubanes with Organolithiums. The Case of 1,4-Cubadiyl. Journal of the American Chemical Society. 112: 876.
Reddy DS, Maggini M, Tsanaktsidis J, Eaton PE. 1990. Direct Radical Substitution on the Cubane Skeleton. Tetrahedron Letters. 31: 805.
Della EW, Taylor DK, Tsanaktsidis J. 1990. Unusual Bridgehead Reactivity: Formation of [1.1.1]Propellane by 1,3-Dehydrobromination of 1-Bromobicyclo[1.1.1]pentane. Tetrahedron Letters. 31: 5219.
Della EW, Tsanaktsidis J. 1989. The Synthesis of Bridgehead Halides by the Barton Decarboxylation Procedure. Australian Journal of Chemistry. 42: 61.
Tsanaktsidis J, Eaton PE. 1989. Synthesis of Iodocubanes by Decarboxylative Iodination. Tetrahedron Letters. 30: 6976.
Della EW, Tsanaktsidis J. 1988. Synthesis of Some Bridgehead Trimethylsilylpolycycloalkanes. Silicon-29 NMR Chemical Shifts and 29Si-13C Coupling Constants. Organometallics. 7: 1178.
Della EW, Tsanaktsidis J. 1988. A Convenient Synthesis of Fluorotrimethylsilane. Synthesis. 407.
Della EW, Pigou PE, Tsanaktsidis J. 1987. Enhanced Solvolytic Reactivity of 1-Bromobicyclo[3.3.1]heptane: Intermediacy of a Stabilised Bridgehead Carbenium Ion. Journal of the Chemical Society, Chemical Communications. 833.
Della EW, Tsanaktsidis J. 1986. Decarboxylation of Bridgehead Carboxylic Acids by the Barton Procedure. Australian Journal of Chemistry. 39: 2061.
Della EW, Tsanaktsidis J. 1985. Synthesis of Bridgehead-Bridgehead Substituted Bicycloalkanes. Australian Journal of Chemistry. 38: 1705.

Contact Information

Dr John Tsanaktsidis
Senior Principal Research Scientist
Materials Science and Engineering
Phone: +61 3 9545 2487

Location

CSIRO Materials Science and Engineering - Clayton

Office: Bayview Avenue
Clayton VIC 3168
Australia









................




Clayton, Victoria, Australia

RAILWAY STATION






 





Moza Corner, opposite to Clayton station




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Dr. Charmy S. Kothari


Dr. Charmy S. Kothari


Nirma Institute.JPG


Educational Qualification M.Pharm., Ph.D.
Research Area Analytical method development, validation, stability studies, impurity profiling, Isolation, identification and characterization of biomarker compounds from plants and formulations.
General information
Designation Assistant Professor
Office Phone 079-30642719
Cabin No UG-103
Email charmy.kothari@nirmauni.ac.in

Assistant Professor,
Dept. of Pharmaceutical Analysis,
Institute of Pharmacy,
Nirma University
 

Dr. Charmy S. Kothari has 10 years of teaching and research experience. She has 16 researches papers and review articles published in reputed Indian and International journals. She has presented various posters and a paper at international, national and state level conferences like GUJCOST, IPC, APA etc, from which one paper awarded 2nd prize for best oral presentation in state level conference Supported by GUJCOST in 2004 and She is also recipient of Dr. P. D. Sethi’s research paper certificate of merit award 2007 for the paper published in J of AOAC International. 

She was awarded first prize for best poster presentation in International conference on Applied Pharmaceutical Analysis, organized by Boston Society in 2014. She has been actively involved in various capacities in organizing National and International Conferences/Workshops. 

She received a financial assistance from GUJCOST worth Rs. 40,000/- to organize workshop on Process Spectroscopy & Chromatography in department of Pharmaceutical Analysis. She is life member of APTI & ISTE. She is a recognized Post Graduate and Ph. D. Guide at Institute of Pharmacy, Nirma University. She has guided 15 M.Pharm students and currently guiding three Ph.D. Students. She received a minor research grants from Nirma University worth Rs.90,000/- in the year 2013 and GUJCOST worth Rs./- 5,00,000 in the year 2014. 

She is reviewer of national & international journal in her research area of interest. Her research areas of interest are analytical method development, validation and stability studies, impurity profiling and Isolation, identification and characterization of marker compounds from plants and formulations.


Current Activities : Currently involved in analytical and bio-analytical method development and standardization of poly-herbal formulation



Dr. Charmy Kothari (Assistant Professor, Department of Pharmaceutical Analysis) of Institute of Pharmacy, Nirma University,
received 2nd Prize in Poster Presentation
at APA (Applied Pharmaceutical Analysis) - INDIA -
International Conference 2015
held at RAMADA Convention Centre, Mumbai
during 23 to 25th February, 2015.
The Poster was Co-authored by ANKIT SHAH.
Poster Title was "Simultaneous Estimation of Gabapentin and Nortriptyline HCl in their Combined Dosage form by UV-Spectrophotometric and Spectroflurometric Methods using Opa-Beta-Mercaptoethanol Derivatization.
Heartily Congratulations to ANKIT SHAH and CHARMY KOTHARI MAM....!!!


Charmy Kothari's profile photoExperience
Teaching 10 Year plus
Industry -



Specialization
Specialization Areas Pharmaceutical Analysis & Quality Assurance
Subject Taught UG Pharmaceutical Analysis III, Pharmaceutical Analysis & Quality Assurance
Subject Taught PG Advanced Instrumental Methods, Pharmaceutical Quality Assurance, Pharmacopoeial Methods of Analysis, Analysis of Biotechnologically Derived Products, Validation in Pharmaceutical Manufacturing


Hobbies
Reading, writing, music
 
 Nirma Institute of Pharmacy
 
AgencyProject TitlePrincipal Investigator (s)Fund TypeProject Status
GUJCOST, GandhinagarIsolation and characterization of marker from polyherbal formulationDr. Charmy S. Kothari, Prof. Priti J MehtaExternal  FundingOngoing
Nirma UniversityStandardization of Polyherbal FormulationDr. Charmy S.        KothariInternal FundingOngoing
.

Experience









Assistant Professor

Institute of Pharmacy, Nirma University
– Present (4 years 3 months)Ahmedabad Area, India55








Acadmics

RPCP, Changa
(1 year 10 months)








Assistant Professor

ASPBRI, Adalaj,Ahmedabad
(1 year 1 month)








lecturer

BMCPER, MODASA
(3 years 4 months
 


Education








C U Shah College of Pharmacy

M.Pharm., Quality Assurance, Distinction








BMCPER

Bachelor of Pharmacy (B.Pharm.)


Dr. Charmy S. Kothari - Qualification


QualificationSpecializationUniversityPassing Year%Class
Ph.D. Pharmaceutical ScienceHemchandracharya North Gujarat University August 2008
M.Pharm. Quality AssuranceS N D T Women's University C U Shah College of Pharmacy August 2004 70.00Dist
B.Pharm. PharmacyHemchandracharya North Gujarat University B M Shah College of Pharmaceutical Education & Research, Modasa May 2002 71.72Dist

Dr. Charmy S. Kothari - Experience


Institute / OrganizationDesignationDuration
Ramanbhai Patel College of Pharmacy, ChangaAssociate ProfessorJanuary 2009 To October 2010
Arihant School of Pharmacy & Bio Research Institute, AdalajAssistant ProfessorSeptember 2008 To January 2009
Arihant School of Pharmacy & Bio Research Institute, AdalajLecturerDecember 2007 To September 2008
B M Shah College of Pharmaceutical Education And Research, ModasaLecturerSeptember 2004 To December 2007



Dr. Charmy S. Kothari - Achievements


TitleDescriptionAchieved On
Bioanalytical Method Development & Validation of Memantin HCl and Donepezil HCl by Spectrofluorimetry 1st Prize for Poster PresentationFebruary 2014
Simultaneous Assay of Olanzapine and Fluoxetine in Tablets by column HPLC and HPTLC Methods Received certificate of merit of the Dr. P.D. Sethi research paper award – 2007.December 2007
Identification of Markers in Kumariasava preparation for quantitative analysis 2nd prize for oral paper presentationDecember 2004

GUJARAT

Dr. Charmy S. Kothari - Publication


International Journal

TitleISSN / ISBN No PublisherVolumeYear
Indigenous plant medicines for health care: Treatment of Diabetes mellitus and Hyperlipidemia 1875-5364Chinese Journal of Natural Medicines12(5): 0335-03442014
Concurrent Estimation of Amlodipine Besylate, Hydrochlorothiazide and Valsartan by RP-HPLC, HPTLC and UV-VIS Spectrophotometry 9306-3968J Chro. Sci.52 (1), 27-352014
Simultaneous Estimation of Atorvastatin calcium and Olmesartan medoxomil in Pharmaceutical Formulation by Reverse phase High-Performance Liquid Chromatography, High-Performance Thin-Layer Chromatography and UV Spectrophotometric methods. 1060-3271J of AOAC International97(3), 791-7972014
Critical review: Significance of Force degradation study with respect to current Pharmaceutical Scenario 0974-4169Asian J. Res. Chem.4(5), 286-2962013
Ratio Derivative Spectrophotometric Method For Simultaneous Estimation Of Olmesartan Medoxomil And Atorvastatin Calcium In Their Combined Tablet Dosage Form 975-1491Inte. J of Pharm. & Pharm. Sci4(5), 222-2262012
Quality Audit: Regulatory Compliance In Pharmaceuticals 2278 – 4357World J of Pharm. & Pharmaceutical Sci.1 (4), 1228-12492012
Method development, validation and forced degradation studies of atomoxetine hydrochloride by RP- HPLC 2229-5054Inte.J. Drug Formu. Res.2 (3), 408-4242011
Development And Validation Of HPTLC Method For The Estimation Of Atomoxetine Hydrochloride In Tablet Dosage Form 2229-5054Inte.J. Drug Formu. Res.2 (5), 292-2982011
Simultaneous Assay of Olanzapine and Fluoxetine in Tablets by column HPLC and HPTLC Methods 1060-3271J AOAC Inte.90 (6), 1573-15782007
Development and validation of HPTLC method for the simultaneous estimation of olanzapine and fluoxetine in tablet dosage form 0972-768 XInte. J of chem. Sci.4(4), 1037-10422006
Standardization of marketed Kumariasava – An Ayurvedic Aloe Vera product 0731-7085J of Pharmaceutical & Biomedical Analysis37 (5), 937-9412005

National Journal

TitleISSN / ISBN No PublisherVolumeYear
Development and Validation of Zero and First Order Derivative Spectrophotometric Methods For Determination of Oxcarbazepine In Pharmaceutical Dosage Forms 2321 – 0966 (Print), 2321 – 0974 (Online)Pharmagene1 (1), 1-62013
Stability Indicating HPTLC Method for the Simultaneous Determination of Olanzapine and Fluoxetine in Combined Pharmaceutical Dosage Form 0250-474XIndian J. Pharm. Sci.70 (2), 251-2552008
Development and validation of a HPTLC method for the estimation of Sumatriptan in tablet dosage form 0250-474XIndian J. Pharm. Sci.70 (6), 831-8342008
Isolation, Identification and Characterization of Aloin in Kumariasava and Aloe Vera by different Analytical Techniques 0019-462XIndian drugs44 (8), 632-6352007
Development and Validation of HPLC Method for the Estimation of Levetiracetam in Tablet Dosage Form 0973-7200J. Pharm. Res.6 (4), 236-2382007


Dr. Charmy S. Kothari - Research Projects


Fund TypeAgencyStart DateDurationPrincipal Investigator
Internal FundingNirma University17/09/20132 YearsPI - Dr. Charmy S. Kothari
External FundingGUJCOST, Gandhinagar03/12/2014Two YearsPI - Dr. Charmy S. Kothari, Prof. Priti J Mehta

Dr. Charmy S. Kothari - Project Guided


Project TitleDescriptionDuration
Standardization of antidiabatic Polyherbal Formulation May 2014
Method Development and Validation of Natamycin using UV Visible Spectroscopy and Forced Degradation Studies using HPLC May 2014
First Order UV Spectrophotometric and RP-HPLC Methods for Determination of Pesticides Residues in vegetables from North GUjarat Region May 2014
Simultaneous Estimation of Gabapentin and Nortriptyline Hydrochloride in their Combined Dosage Form by UV Spectrophotomrtric and Spectrofluorimetric Methods using OPA Beta Mercaptoethanol Derivatization May 2014
DEVELOPMENT AND VALIDATION OF UV-SPECTROPHOTOMETRIC, SPECTROFLUORIMETRIC METHODS FOR SIMULTANEOUS ESTIMATION OF MEMANTINE HYDROCHLORIDE AND DONEPEZIL HYDROCHLORIDE USING OPA- ß - MERCAPTOETHANOL DERIVATIZATION May 2012
Development and Validation of Stability Indicating RP-HPLC Method for Assay and Dissolution of an Anti-psychotic drug in its Tablet Dosage Form May 2012
DEVELOPMENT AND VALIDATION OF STABILITY INDICATING RP-HPLC METHOD FOR ESTIMATION OF DRUG D7552 USED IN CONGESTIVE CARDIAC FAILURE IN I.V. DOSAGE FORM May 2012
Development and Validation of Stability indicating HPTLC method of Esomeprazole Magnesium Trihydrate in its Bulk Form. May 2012
Simultaneous Estimation of Atorvastatin calcium and Olmesartan medoxomil in Pharmaceutical Formulation by Reverse phase High-Performance Liquid Chromatography, High-Performance Thin-Layer Chromatography and UV/Vis Spectrophotometric methods May 2011
Development and validation of UV Visible spectrophotometric, HPTLC and RP-HPLC methods for simultaneous estimation of Amlodipine besylate, Hydrochlorthiazide and Valsartan in their combined dosage forms May 2011

 
LINKS

charmy.kothari@nirmauni.ac.in

 https://www.facebook.com/charmy.kothari


 in.linkedin.com/pub/charmy-kothari/12/5aa/9bb


https://plus.google.com/103499848607956347435/posts


  Journal............http://www.nirmauni.ac.in/IPNU/JournalNUJPS


 READ.............http://www.nirmauni.ac.in/Upload/IPNU/Documents/NUJPS%20January%202014_02052014_114247PM.pdf

 https://charmykothari.wordpress.com/

https://www.researchgate.net/profile/Charmy_Kothari2/info

 Dr. Charmy S. Kothari has 10.7 years of teaching and research experience. She has 18 researches papers and review articles published in reputed Indian and International journals. She has presented various posters and a paper at international, national and state level conferences like GUJCOST, IPC, APA etc, from which one paper awarded 2nd prize for best oral presentation in state level conference Supported by GUJCOST in 2004 and She is also recipient of Dr. P. D. Sethi’s research paper certificate of merit award 2007 for the paper published in J of AOAC International. She was awarded first and second prize for best poster presentation in International conference on Applied Pharmaceutical Analysis, organized by Boston Society in the year 2014 and 2015, respectively. She has been actively involved in various capacities in organizing National and International Conferences/Workshops. She received a financial assistance from GUJCOST worth Rs. 40,000/- to organize workshop on Process Spectroscopy & Chromatography in department of Pharmaceutical Analysis. She is life member of APTI, IPA & ISTE. She is a recognized Post Graduate and Ph. D. Guide at Institute of Pharmacy, Nirma University. She has guided 15 M.Pharm students and currently guiding three Ph.D. Students. She received a minor research grants from Nirma University worth Rs.90,000/- in the year 2013 and GUJCOST worth Rs./- 5,00,000 in the year 2014. She is reviewer of national & international journal in her research area of interest. Her research areas of interest are analytical and bioanalytical method development, validation and stability studies, impurity profiling and Isolation, identification and characterization of marker compounds from plants and formulations.





 Shri Narendra Modi speaks on E-Governance at Nirma University

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October 26-28, 2015 Hyderabad, India

4th International Summit onGMP, GCP & Quality




Biography

Charmy S Kothari has 11 years of teaching and research experience. She published 18 researches papers. Three research presentation awards. Additionally, she is the recipient of Dr P D Sethi’s Research Paper Certificate of Merit Award 2007. She received a financial assistance from GUJCOST worth Rs. 40,000 to organize workshop on Process Spectroscopy & Chromatography. She received a Minor Research Grants from Nirma University worth Rs. 90,000 and GUJCOST worth Rs. 5,00,000. Her areas of research interest are analytical and bioanalytical method development by QBD approach, validation and stability studies, impurity profiling and Isolation, identification and characterization of marker compounds from plants and formulations.

Abstract

Herbal medicines have a long therapeutics history and are still serving the need. However, the quality control of herbal medicines still remain a challenge because of the complex nature of the phytoconstituents. The aim and objective of the study is identification of biomarker for qualitative and quantitative analysis of polyherbal formulation containing Arjuna, Guggul & Pushkarmoola in combined dosage form. The poly herbal formulation was evaluated for physical parameters, organoleptic parameters and physicochemical parameters as per AYUSH and WHO guidelines. Quantification of constituent was done by developing and validating High Performance Thin Layer Chromatography (HPTLC). The HPTLC method was developed and validated for poly herbal formulation in the methanol extract. HPTLC separation was achieved on precoated silica gel 60F-254 using Toluene : Ethyl Acetate (8:2 v/v) as mobile phase. Polyherbal formulation methanolic extract gave the peak of E and Z guggulsterones at Rf value 0.34 and 0.41, respectively. Which was further confirmed with reference standard. Assay % of E and Z guggulsterones was found to be 81% and 83%, respectively. Spots of E and Z guggulsterones from polyherbal formulation was isolated for identification. Identification was confirmed by mass spectrometry. Hence, E and Z guggulsterones can be used as a biomarker controlling quality of polyherbal formulation containing Arjuna, Guggul & Pushkarmoola in combined dosage form.
- See more at: http://gmp-gcp-quality-control.pharmaceuticalconferences.com/speaker/2015/charmy-s-kothari-nirma-university-india#sthash.QQRVdGNl.dpuf
 

 


With Rushvi Patel, Manisha Rajpurohit, Charmy Kothari, Debashish Sarkar, Chandni Doshi and Shashank Jain at The Fern.


 Shri Narendra Modi speaks on E-Governance at Nirma University

 

 #‎NationalSeminar‬ ‪#‎CTD‬ ‪#‎IPNULeads2015‬

The Department of Pharmaceutical Analysis, Institute of Pharmacy, Nirma University, organized a National Seminar on
'CTD: TECHNICAL & REGULATORY REQUIREMENT'
on
26 SEP 2015

supported by CCE, Nirma University Ahmedabad

Dr. Manjunath Ghate, Director, Institute of Pharmacy, Nirma University, was the Chair Person
Prof. V. R. Iyer, Director, CCE, Nirma University, presided over the function.
Dr. Priti Mehta and Dr. Charmy Kothari were the Coordinators for the workshop.
We had Dr. Arvind Mishra, Senior Vice President, International Regulatory Affairs, Claris Injectables Ltd., Ahmedabad as the Chief Guest for the inaugural function. He spoke about the regulatory compliance which is needed for pharma industry. He also gave an overview of CTD.
We thank the eminent speakers who were present at the event.
▶ Dr. Priyanka Pawar, GM, Regulatory affairs, Amneal Pharmaceuticals
She discussed about CTD Vision, Construction and Application in Context of Regulatory Submission. She also focused on requirement and importance of eCTD submission and procedure.
▶ Dr. Vaishali Kothari, DGM, International Regulatory Affairs, Zydus Cadila Healthcare LTD delivered a lecture on CTD, CTD modules in detail and an overview of eCTD.
She also highlighted the Compilation of Safety and Efficacy Data: CTD Module 4 and 5.
▶ Dr. Manish Yadav focused on recent trends of Bio-­deficiencies while giving real examples of the same.
▶ Dr. Hemant Kumar Jaju delivered a talk on 'Learning from Past CTD Submissions'. He explained in detail about the queries generated by auditors during CTD evaluation.
The seminar had active participation from Academics and the Pharma Industry and received excellent feedback.
We thank everyone who was present for this exceptionally organized seminar.

 

 

 

 

 

 

GOTA, AHMEDABAD

 

 

Gota is located in Gujarat


References

  1. "Nirma University Campus".
  2. "Private Universities in Gujarat homepage".
  3. http://www.nirmauni.ac.in/
  4. "Nirma University Infrastructure and other details".
  5. "Top Engineering Colleges". Outlook India. 16 June 2012. Retrieved 17 June 2012.
  6. "GHRDC-CSR Engineering Colleges Survey 2013" (PDF). Competition Success Review (Competition Success Review and the Global Human Resources Development Centre): 1–6. July 2013.
  7. "Top 50 Private Engineering Colleges of 2009" (PDF). Mint. 23 June 2009. Retrieved 9 September 2011.

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Alleppey kerala.....Alappuzha INDIA

Alappuzha - Wikipedia, the free encyclopedia

en.wikipedia.org/wiki/Alappuzha
pronunciation (help·info)), also known as Alleppey, is the administrative headquarters of Alappuzha District of Kerala state of southern India. Alappuzha is the ...
 
Map of alleppey.
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 Table in restaurant after eating fish, Alleppey, Kerala, India, South Asia,
 
 
 
 
 
 
 PAGODA RESORTS ALLEPPEY KERALA INDIA
 
 

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