One Organic Chemist One Day............Honouring Profiles of leading Organic Chemists brought to you by DR ANTHONY MELVIN CRASTO, worlddrugtracker, helping millions, amcrasto@gmail.com, +91 9323115463, India, skype amcrasto64
DR ANTHONY MELVIN CRASTO Ph.D ( ICT, Mumbai) , INDIA 29Yrs Exp. in the feld of Organic Chemistry,Working for GLENMARK PHARMA at Navi Mumbai, INDIA. Serving chemists around the world. Helping them with websites on Chemistry.Million hits on google, world acclamation from industry, academia, drug authorities for websites, blogs and educational contribution
She completed her Ph.D. in the research group of Prof.
Xingguang Su at Jilin University China, in the field of Analytical
Chemistry. She is having 10 international publications with cumulative
impact factor of 20. Synthesis (hydrothermal, microwave assisted),
stabilization, self assembly, characterization and analytical
applications of nanomaterials particularly gold and silver nanoparticles
are major focus of her research at ICCBS. A number of analytical
protocols are being performed in her research group such as biosensors,
layer by layer assembly, lab-on-chip, luminescence and colorimetric
analysis and nanoparticles involved immunoassays. Drug coated
nanoparticles assembly and their biological applications are another
field of interest. Moreover CdTe, CdSe quantum dots based analysis are
also among her group’s expertise.
Areas of Research: Nanotechnology, Synthesis and Applications
Shamsa Kanwal
Shamasa
Kanwal joined the lab in 2007 for her Doctoral research. Her reaserch
focus on the application of flow injection analysis and Chemiluminscence
for detection of various analytes.Her current position is Assistant
Professor at HEJ research institute of Chemistry, Karachi University,
Pakistan.
Assistant Professor at HEJ, ICCBS, University of Karachi
Ph.D. (Organic Chemistry,
Graz, Austria)
Assistant Professor
BRIEF
Dr. Jamshed Hashim conducted his
doctoral studies (2004-2008) on the synthesis of quinolone/bisquinolone
derivatives and postdoctoral research (2008-2009) on the synthesis of
bio-active heterocycles from the Karl Franzens University of Graz,
Austria under the supervision of Professor C. Oliver Kappe. He is a
co-author of 10 high ranked international publications (C.I.F. 33.57).
He was also involved in the area of microwave chemistry (2004-2009) at
the Christian Doppler Laboratory for Microwave Chemistry (CDLMC),
University of Graz, Austria.
He has experience on a variety of dedicated
microwave instruments which he now intend to employ for the efficient
and high yielding synthesis of important organic compounds.
S.I.,T.I., Khawarizmi Laureate
Distinguished National Professor
D. Sc. ( Karachi),
Ph.D. (Organic Chemistry, Karachi)
E-mail: bina.siddiqui@iccs.edu
E-mail:siddiqui_bina@yahoo.com
Telephone: 111-222-292 Ext: 191
Office/Lab: HEJ-208
BRIEF CITATION
Her area of research includes:
i)
Discovery of new molecules bearing potential significance in medicine
and agriculture from indigenous plant materials and elucidation of their
structures by sophisticated spectroscopic methods as well as chemical
transformations. ii) Investigation of their biological and medicinal
potential such as anti-cancer, anti-AIDS, anti-tuberculosis,
anti-leishmaniasis, CNS stimulant and depressant, antihypertensive,
antibacterial, antifungal, analgesic, anti-oxidant and antiplatelet
aggregation activity. iii) Preparation of new synthetic analogues of
natural and synthetic molecules with the object of obtaining lead
bioactive molecules and study their structure-activity-relationship
(SAR). iv) Phytochemical analysis of major active principles in
plants with respect to climatic variations. v) Development and
formulation of biopesticides (bio-insecticides) for use in agriculture,
horticulture and household.
INSTITUTION H.E.J. Research Institute of Chemistry
University of Karachi, Pakistan
Fax #+92-21-34819018-19
E-mailbina@khi.comsats.net.pk/ binahej@yahoo.com
Telephone #+92-21-99261716 (Office
Dr. Bina Shaheen Siddiqui
Dr. Bina Siddiqui is a motherly scientist who has made many important
contributions in the field of medicine and agriculture through her
study and classification of native plants. Muslim Science categorized
her in ‘Pioneers’.
She has been awarded 12 patents for anti-cancer constituents and
biopesticides and has written more than 250 research articles. Pakistan
Academy of Sciences elected her as a Fellow. She has to her credit the
co-founding of the Third World Organization for Women in Science.
Her area of research also includes discovery of new molecules
important in medicine and agriculture and preparation of bioactive
molecules among many other topics.
Ph. D. (Organic Chemistry, Karachi) Associate Professor
E-mail:raza.shah@iccs.edu E-mail:raza_shahm@yahoo.com Telephone: 111-222-292 Ext: 233 Office: Room TWC-203
Over 100 Research
Publications. Current research interest includes synthesis of
interlocked molecules with unique topology and development of artificial
ion channels on the principles of synthetic supramolecular chemistry.
The intelligent orientation of various rings like porphyrins,
calix[n]arenes and cyclodextrins can be exploit to form ion channel with
interesting properties. Functionalization of gold nanoparticles is
another area of interest.
• Over 12 years of experience working within a laboratory of industry and academic environment. Successfully completed graduate program in organic chemistry and postdoctoral fellow in organic and polymer chemistry from University of Alberta.
• Skilled in collecting and interpreting data from Spectroscopic techniques such as nucleic magnetic resonance (NMR), infrared spectroscopy (FTIR), gas chromatography-mass spectroscopy(GC-MS), normal and reverse phase high performance liquid chromatography (HPLC) and gel permission chromatography (GPC), differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), dynamic mechanical analysis (DMA) and texture Analyzer.
• Ability to plan organic synthesis projects with optimised route and high yield based on 10 years’ experience. Hands-on experience in synthesis, purification, separation and characterization of small molecules, monomers and polymers including bio-based chemicals.
• Computer proficiency in database searching (Beilstein, and SciFinder), Microsoft Office, Endnote, Isis Draw, Chem draw and ACD lab. Advanced skills using computers to perform mathematical calculations using Excel and Sigma plot software.
• Excellent analytical writing skills also demonstrated through drafting of winning proposals for research funding worth up to $275,000, such as CFI and NSERC engage. Strong oral communicational skills as demonstrated by extensive experience delivering presentations, scientific reports and lectures to supervisor, industry funders, colleagues and students.
• Solid team player who is also highly self-motivated and able to work independently. Extensive experience working as part of multidisciplinary teams.
• Studied oxidation reactions on different beta-carotenoid compounds, purification and characterization using GCMS, LCMS, FTIR, and NMR
• Prepared different libraries on GCMS based on oxidation reactions of various beta-carotenoid compounds
. • Demonstrated the advanced organic synthesis (Chem3102H), Introductory Chemistry I (Chem1000H) and Introductory Chemistry II (Chem1010H) labs to undergraduate students
• Trained and supervised more than one hundred undergraduate students’ laboratory project in safe environment, which resulted no injury and accident for students. Evaluated students on their lab reports
• Followed and raised awareness regarding safety guidelines and predicted the danger of specific chemical reactions in the lab to prevent any problem
• Wrote and revised proposals under the Professor’s supervision for granting agencies and foundations resulted in two accepted grants of CFI and NSERC-Engage worth $ 275,000 to conduct research on study of biogas digestate as a source of Nitrogen and Phosphate in crop production (NSERC-Engage)
• Planned and led the setup of a new lab, including purchasing instruments, glassware, accessories and chemicals and preparing various inventories for equipment, chemicals and samples
• Prepared of monthly progress report of project for NSERC and weekly progress reports to supervisor, including making recommendations on key activities and priorities for the upcoming week
• Arranged meetings with industry partners including distributing meeting agenda, coordinating logistics, writing the minutes and following up with participants
• Kept record of various budget funding and communicated with University’s financial service and companies, for envelopes worth up to $ 850,000
• Extracted soil samples and measurement of Nitrate, Ammonium and Phosphate ions concentration by Microplate spectrophotometer followed by analyzing the data in order to study of biogas digestate as a source of nutrient in crop production
• Performed literature reviews, prepared scientific proposals and planned the best route in synthesise of chemicals and bio-polymers from renewable resources
• Carried out organic reactions followed by purification and characterization of compounds by NMR, FTIR and Mass spectroscopy
• Collected, interpreted and analyzed data of HPLC, GC, GPC, NMR, FTIR and Mass spectroscopy, DSC, TGA, DMA and Texture analyzer
• Presented research results in scientific international conferences and group meetings with industry partners and prepared and revised of three manuscripts for publishing on vegetable oil based biomaterials
• Supervised and assisted three graduate students in planning their project experiments and writing scientific manuscripts and thesis
Trent University :: Biomaterials Research Laboratory
• Proposed the synthesis route of biobased Diisocyanates from Oleic acid and prepared thermosetting and thermoplastic polyurethanes entirely from biobased feedstock
• Characterized various synthesised diisocyanates and polyols by GC, HPLC, NMR, FTIR and Mass spectroscopy
• Identified and investigated the polymers’ physical and mechanical properties by GPC, DSC, TGA, DMA and Texture analyzer to characterize the physical properties of lipid-based polymers
• Prepared three scientific papers and revised based on supervisor and reviewers comments
• Collected and analysed all the data from NMR, HPLC, LC-MS and GC-MS
• Prepared and revised the manuscript to be published in chemistry journals
• Proposed the novel organocatalytic methodology for the synthesis of chiral benzopyranes for which the published paper was awarded as the most cited paper in Tetrahedron Asymmetry journal Synthesised organocatalysts from amino acids followed by purification and characterization using LC-MS and NMR spectroscopy
• Performed the application of organocatalysts in asymmetric organic reactions and separation of enantiomers with chiral HPLC
• Managed a group of 12 employees including analytical chemist, technicians and interns
• Revised and updated SOPs and prepared formal reports of the suspected sample’s analysis for relevant customers
• Arranged and participated in technical training of new hires and interns and provided technical advice to the colleagues based on day-to-day operations
• Optimized staff schedules and coordinated the workflow, equipment maintenance and supplies inventory to minimize down the time and allow the laboratory met deadlines
• Extracted biological samples such as urine and blood followed by TLC analysis based on SOPs to determine the presence of alkaloids such as morphine and codeine as a proof addiction to drug. Analyzed alkaloids such as morphine, codeine and heroin from opium and suspected solid samples of crime scene by TLC and HPLC and sent the result to courts in order to the judges to determine the quantity and quality of accuser’s charge
• Identified methadone, amphetamine, methamphetamine, cocaine in samples from crime scene by HPLC
• Performed of teaching assistant of Organic Qualitative Analysis and Organic chemistry I & II Laboratory
• Delivered tutorial sessions of Organic chemistry II
• Supervised more than one hundred undergraduate students’ lab work including safety advice and procedure demonstrating. Evaluated students by lab reports and quiz results
Enhancement of thermal stability, strength and extensibility of lipid-based polyurethanes with cellulose-based nanofibers
Polymer Degradation and Stability 10/2012; 97(10):1970–1978.
Synthesis and physical properties of lipid-based poly(ester-urethane)s, I: Effect of varying polyester segment length
Polymer. 08/2012; 53(17):3762–3771
Controlling Product Composition of Metathesized Triolein by Reaction Concentrations
J Am Oil Chem Soc (2012) 89:2077–2089
Novel long chain unsaturated diisocyanate from fatty acid: Synthesis, characterization, and application in bio‐based polyurethane
Journal of Polymer Science Part A Polymer Chemistry 06/2010; 48(15):3302 - 3310
Functional thermoplastics from linear diols and diisocyanates produced entirely from renewable lipid sources
Biomacromolecules 03/2010; 11(4):911-8
Fatty acid-derived diisocyanate and biobased polyurethane produced from vegetable oil: synthesis, polymerization, and characterization
Biomacromolecules 04/2009; 10(4):884-91
Synthesis and application of novel imidazole and 1 H-tetrazolic acid containing catalysts in enantioselective organocatalyzed Diels–Alder reactions
Tetrahedron Asymmetry 01/2009; 20(16):1871-1876
An efficient synthesis of fused polycyclic indole derivatives via Aldol-Hetero Diels-Alder reaction of α,β-Unsaturated Thio-oxindoles with various dienophiles
Journal of the Iranian Chemical Society 8(1) 2011, 265-271.
A tandem Aldol-Diels-Alder reaction accelerated in water: An approach to the Catalyst-Free One-Pot synthesis of spiro Thio-Oxindoles
Journal of the Iranian Chemical Society 7(3), 2010, 781-790
A novel synthesis of some 2‐imino‐4‐thiazolidinone derivatives
Journal of Heterocyclic Chemistry 03/2009; 44(1):35 - 38
A new eco-friendly and efficient mesoporous solid acid catalyst for the alkylation of phenols and naphthols under microwave irradiation and solvent-free conditions
Scientia Iranica 01/2009; 16(2 C):81-88
A New Imidazole‐Containing Imidazolidinone Catalyst for Organocatalyzed Asymmetric Conjugate Addition of Nitroalkanes to Aldehydes
Research Focus: Synthesis and purification of fatty acid-derived diisocyanates from oleic acid via Curtius rearrangement followed by their application in the synthesis of biobased thermosetting and thermoplastic polyurethanes.
Ph.D. (Organic Chemistry), Sharif University of Technology. Tehran, Iran
As an organic
chemist, Dr. Leila Hojabri synthesizes biomaterials from agricultural
sources – making products that are much “greener” than those from
petroleum-based materials.
Dr. Hojabri is excited
about the great potential of these materials to help make a more
environmentally sustainable society. She would like to further explore
synthesizing lubricants and waxes from lipid.
Dr. Hojabri is delighted to be able to work in such satisfying
collaboration with other researchers in the group, and challenges
herself to stay as up-to-date as possible on developments in her field
in order to bring as much knowledge as possible to these collaborations.
She really enjoys the opportunity to exchange information with the
other researchers, and finds the process helps her to understand and
appreciate her colleagues’ fields of inquiry.
With a firm commitment to both the environmental
sciences and interdisciplinary approaches, Dr. Hojabri is excited, too,
by the great potential for this kind of broad-reaching, world-changing
research at Trent.
Coming from two years at the University of
Alberta in Edmonton, Dr. Hojabri finds Peterborough a green, beautiful
and relatively peaceful place. As of her first fall in Ontario, she even
likes the weather.
After amazing visits to Niagara Falls, Jasper and
Banff, Leila and her family crave more travel. Next up: la belle
province, Quebec.
Dr. Leila Hojabri Broujerd, Iran Research Associate
Ph.D. (Organic Chemistry), Sharif University of Technology. Tehran, Iran
As an organic
chemist, Dr. Leila Hojabri synthesizes biomaterials from agricultural
sources – making products that are much “greener” than those from
petroleum-based materials.
Dr. Hojabri is excited
about the great potential of these materials to help make a more
environmentally sustainable society. She would like to further explore
synthesizing lubricants and waxes from lipid.
Dr. Hojabri is delighted to be able to work in such satisfying
collaboration with other researchers in the group, and challenges
herself to stay as up-to-date as possible on developments in her field
in order to bring as much knowledge as possible to these collaborations.
She really enjoys the opportunity to exchange information with the
other researchers, and finds the process helps her to understand and
appreciate her colleagues’ fields of inquiry.
With a firm commitment to both the environmental
sciences and interdisciplinary approaches, Dr. Hojabri is excited, too,
by the great potential for this kind of broad-reaching, world-changing
research at Trent.
Coming from two years at the University of
Alberta in Edmonton, Dr. Hojabri finds Peterborough a green, beautiful
and relatively peaceful place. As of her first fall in Ontario, she even
likes the weather.
After amazing visits to Niagara Falls, Jasper and
Banff, Leila and her family crave more travel. Next up: la belle
province, Quebec.
////
Shamasa Kanwal joined the lab in 2007 for her Doctoral research. Her reaserch focus on the application of flow injection analysis and Chemiluminscence for detection of various analytes.Her current position is Assistant Professor at HEJ research institute of Chemistry, Karachi University, Pakistan.
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