One Organic Chemist One Day............Honouring Profiles of leading Organic Chemists brought to you by DR ANTHONY MELVIN CRASTO, worlddrugtracker, helping millions, amcrasto@gmail.com, +91 9323115463, India, skype amcrasto64
DR ANTHONY MELVIN CRASTO Ph.D ( ICT, Mumbai) , INDIA 29Yrs Exp. in the feld of Organic Chemistry,Working for GLENMARK PHARMA at Navi Mumbai, INDIA. Serving chemists around the world. Helping them with websites on Chemistry.Million hits on google, world acclamation from industry, academia, drug authorities for websites, blogs and educational contribution
Mishra A, Goel RK. Comparative
behavioral and neurochemical analysis of
phenytoin and valproate treatment on epilepsy induced learning and
memory deficit: In search for add on therapy. Metabolic Brain Disease
DOI: 10.1007/s11011-015-9650-8 (Impact Factor 2.39)
Mishra A, Goel RK. Adjuvant anticholinesterase
therapy for the management of epilepsy induced memory deficit: A
critical preclinical study. Basic and Clinical Pharmacology and
Toxicology 2014; 115: 512-517. (Impact Factor 2.29)
Mishra A and Goel R.K.,
Psychoneurochemical investigations to reveal neurobiology of memory
deficit in epilepsy. Neurochemical Research 2013; 38: 2503-2515.
Choudhary KM, Mishra A, Goel RK.
Ameliorative effect of Curcumin on seizure severity, depression like
behavior, learning and memory deficit in post pentylenetetrazole-kindled
mice. European Journal of Pharmacology 2013; 704: 33-40.
Singh D, Mishra A, Goel RK. Effect
of saponin fraction from Ficus religiosa on memory deficit, behavioral
and biochemical impairments in pentylenetetrazol kindled mice.
Epilepsy and Behavior 2013; 27: 206-211.
Chaudhary A, Das P, Mishra A, Kaur
P, Singh B, Goel RK. Naturally occurring himachalenes to
benzocycloheptene amino vinyl bromide derivatives: as antidepressant
molecules. Molecular Diversity 2012; 16: 357-366.
Mishra A, Goel R.K. Age Dependent
Learning and Memory Deficit in PTZ Kindled Mice. European Journal of
Pharmacology 2012; 674: 315-320.
Singh B, Mishra A, Goel R.K.
Anticonvulsant Activity of Passiflora incarnata - No Role of Chrysin.
Journal of Pharmaceutical Negative Research 2011; 2: 51-54.
Mittal M, Mishra A, Goel R.K. Role
of GABAA Antagonism in Antidepressant Effect of Novel 2-Azetidinone.
Medicinal Chemistry Research 2010,19: S57-S58.
Mishra A, Bhatti R, Singh A, Ishar MPS. Ameliorative Effect of the Cinnamon Oil from Cinnamomum zeylanicum upon Early Stage Diabetic Nephropathy, Planta Medica 2010; 76: 412-417
International Travel Grant from Indian Council of Medical Research, New Delhi, India, to attend Neuroscience-2013 San Diego, CA, USA
International Travel Grant from Department of Science and Technology, New Delhi, India, to attend 22nd Neuropharmacology Conference, New Orleans, LA, USA
3rd Prize in Oral Presentation at National Conference on Drug Innovation: Emerging Trends and Challenges" (Feb 2012)
Award of Senior Research Fellowship and IndividualResearch Project entitled “To Study the Neurobiology of Epilepsy Induced Cognitive Deficit and Possible Treatment Approaches” from Indian Council of Medical Research (ICMR), New Delhi
Life-time Member of Indian Pharmacological Society (LM-297)
Life-time Member of Indian Academy of Neuroscience (LM-110)
Life-time Member of Laboratory Animal Science Association of India (L-406)
Member of American Academy of Neurology
Member of Society for Neuroscience
Member of Italo-LatinAmerican Society of Ethnomedicine
Member of Board of Studies for the Discipline of Pharmaceutical Sciences of Lovely Professional University, India
Graduate Aptitude Test in Engineering qualified (2005: AIR-1313; 2006 AIR-909)
1st Prize in one week training program for Analytical
Technique and Instrumentation under Capacity Building Project (sponsored
by the Ministry of Health & Family Welfare, GOI) in National
Institute of Pharmaceutical Education and Research (NIPER) from 20–24
March 2006
5th Position in University Merit List, Punjab Technical University, Jalandhar in B. Pharmacy
Lettuce Lake Park is a 240-acre (97 ha) Hillsborough County-run park
just outside the city limits of Tampa, Florida. It is located on
Fletcher Avenue between Interstate 75 and the University of South
Florida. The park opened in 1982.
Lettuce Lake Park features
several boardwalks that wind through a variety Florida ecosystems; a
fresh water wetland and flood plain, an oak-dominated hardwood forest,
cypress domes, and the Hillsborough River. The park also contains a
visitor's center, an observation tower, nature trails, picnic tables,
barbecue pits, restrooms, an open play field, and a playground.
Photography all the way done by Dr. Sanjay Kumar.. Great skills
Hayes Group sweeps poster awards at SciX 2015 held in Providence, RI
The SciX 2015 Conference (Federation of Analytical Chemistry and
Spectroscopy Societies) was held from September 27 to October 2 at the
Rhode Island Convention Center at Providence, RI.
Leading
researchers convened to present their cutting edge developments in
analytical sciences, instrumentation and unique applications. The
meeting hosted a world-class exhibition, presentations from leading
scientists, educational courses, and many networking opportunities.
The Hayes group had a clean sweep of the American Electrophoresis
Society poster awards with Claire Crowther 1st, Shannon (Huey) Hilton
2nd and Jie Ding receiving an Honorable Mention. Jie Ding also received
3rd place for the conference wide FACSS Student Poster AWard.
This was a very strong showing for ASU's School of Molecular Sciences.
Prabhat Arya grew-up on the University of Delhi campus where
he received his education (BSc Hons, MSc, MPhil, PhD, 1974-85).
Following post-doctoral tenures (1985-89) with Professors Robert Corriu
(Univ of Montpellier, France), Ian Paterson, FRS (Cambridge Univ) and
Bill Chan (McGill Univ), he then joined the National Research Council of
Canada, Ottawa and quickly climbed the ranks, and, worked with this
organization for nearly 20 years. Later, he accepted a challenge to help
the newly created institute, Ontario Institute for Cancer Research
(OICR), to establish the Medicinal Chemistry Program. His long-standing
quest to establish a Translational Chemical Biology Program that can
stand at the international level, finally brought him to India in July
2009.
He started his India academic journey at the Institute of Life
Sciences (later, renamed as the Dr. Reddy’s Institute of Life Sciences),
located on the beautiful University of Hyderabad campus.
With an objective to building a novel chemical toolbox
having small molecules that are more close to bioactive natural
products, his team develops novel synthesis methods. Here the general
goals are to develop methods that allow to access small molecules having
some of the privileged sub-units of bioactive natural products and can
be classified in the category of hybrid natural products. These
compounds, in general, are having sufficient complexity to be easily
workable in the drug discovery arena.
In particular, his team is
building a toolbox having a diverse set of natural product-inspired
macrocyclic compounds. Some of the key sections of bioactive natural
products that his team is working on include: eribulin, rapamycin/FK506,
epothilone, radicicol and salinomycin etc. Through working in a close
partnership with several biomedical researchers, this toolbox is then
thoroughly subjected to a wide variety of cell-based and zebrafish
assays in a hunt for modulators of Protein-Protein Interactions (PPIs)
and signaling pathways.
Over the years, his team has written several
authoritative articles on the need to strengthen the advanced organic
chemistry efforts for producing natural product-inspired chemical probes
to explore their utilization in the signaling biology arena. To date,
he has published 90 peer reviewed research articles, presented 130
invited talks and trained more than 55 post-doctoral fellows and several
graduate and undergraduate students. During his tenure in Canada, he
has served at various national and international committees dealing with
grants and for developing science policies and has won several awards.
Prior to his move to India, He was also an Adjunct
Professor with Chemistry Dept, University of Ottawa, Biochemistry Dept,
McGill University, Affiliate Investigator, Ottawa Hospital Research
Institute (OHRI) and Member, Ottawa Institute of Systems Biology.
He enjoys spending time with his students, other team
members, and, loves sharing his vision and research plans in India.
Often, he can be seen cycling on adventurous Indian roads and is having a
lot of fun while testing his on and off road skills. He is also keen
on promoting the bicycle culture and the need to do a regular exercise
to stay on top of the India hectic life!
DRILS
ABOUT DRILS
The Dr. Reddy's Institute of Life Sciences was conceived in the context of globalization, to foster research competence in India and to bridge the divide between academic research and the pharmaceutical & biotechnology industries.
The institute was incorporated as a non-profit entity under Section 25 of the Indian companies act, facilitating operational autonomy. Construction of the DRILS building comprising 44 labs and an administrative block and spanning ~130,000 sq.ft. in area, began in 2004 and was completed in January 2007.
The institute was inaugurated as a public-private partnership research institute on 29th January 2007, a culmination of the efforts and initiative of the Andhra Pradesh state government, Dr. Reddy's laboratories and the University of Hyderabad. The institute is located in the southeast corner of the campus of the University, one of the largest and greenest campuses in India.
Prabhat Arya,
Professor and Head,
Dr Reddy's Institute of Life Sciences
With an objective to moving
beyond the traditional chemical space and to building a toolbox with
small molecules that are more close to bioactive natural products, Dr
Arya’s team is working in this area for nearly two decades. These
compounds can be broadly defined as natural product-inspired and hybrid
natural products.
Over the years, his team has written several leading
articles on the need to strengthen the advanced organic chemistry
efforts to producing next generation small molecules to undertake
challenging biological targets that are related to protein-protein
interactions (PPIs) and, signaling pathways, in general.
Dr Arya has
trained more than 50 post-doctoral fellows, several graduate and
undergraduate students on this topic and delivered 140 lectures at
various scientific meetings and research institutions. During his
academic tenure in Canada, he served on various NIH and CIHR and NCIC
(Canada) grant panels and worked in the committees that were assigned
the task of establishing large scale chemical biology research programs
within US and Canada.
Prior to making an adventurous move to India in
July 2009, Dr Arya was a Research Officer (at various levels) at the
National Research Council of Canada (NRCC) for nearly 20 years and had a
brief stint at the Ontario Institute of Cancer Research help building
the medicinal chemistry program. In addition, he was an Adjunct
Professor at Biochemistry, McGill University, Chemistry and
Biochemistry, University of Ottawa and Ottawa Health Research Institute
(OHRI).
SignMod
Pharmaceuticals Inc. is an Indian drug discovery company focused on the
synthesis of natural product-inspired (NPI) small molecules which
interrupt protein-protein interactions (PPI) and modulate intracellular
signaling pathways. This class of molecules is the next wave of
marketable pharmaceutical therapies for conditions of high unmet needs
such as cancer, neurodegeneration, inflammation, diabetes/metabolic
disorders, infections and cardiovascular disorders. SignMod has
unparalleled synthetic organic chemistry technology with the ability to
produce high bioactivity small molecule libraries currently inaccessible
to big pharma.
It is well recognized that numerous disease families including cancer,
stroke, immune deficiency, neurodegeneration and diabetes involve
intracellular signaling pathways that are integrated via multiple,
dynamic protein-protein interactions. Disruption of these interactions
using small molecules promises to create tremendous opportunities for
developing new therapeutic approaches for treating these disease
families.
The company proposes to utilize highly specialized, unique capabilities
in high throughput, diversity-oriented synthesis (DOS) in building a
highly functionalized bicyclic to polycyclic and macrocyclic “natural
product-inspired” small molecule toolbox. SignMod toolbox is unique,
filled with compounds that occupy uncrowded chemical space due to their
3-Dimensional (3-D) natural product-inspired architectures, and they
demonstrate superior hit rates (compounds with biological activity)
versus conventional combinatorial libraries.
For further information on SignMod, visit our website: www.signmodpharma.com
– Present (6 years 5 months)University of Hyderabad Campus, Hyderabad, India
My
long-standing quest to establish a chemical biology program in India
recently brought me back to my roots. I am thoroughly enjoying the
challenges of establishing this program at the Dr. Reddy's Institute of
Life Sciences, located on the University of Hyderabad campus.
With the objective of exploring new chemical space, my research aims to
develop novel methods leading to building a natural product-inspired
chemical toolbox. Small molecules from my group are then subjected to a
wide variety of evaluation programs in a hunt for chemical modulators of
protein-protein interaction-based signaling pathways related to cancer,
metabolic disorders, infectious diseases and neurological disorders.
Over the years, we have written several authoritative articles on the
need to strengthen the advanced organic chemistry efforts for producing
natural product-inspired chemical probes to explore their utilization in
the signaling biology arena.
For further detailed information, see our website: www.prabhatarya.org
: Madhu Aeluri
: GVKBio Hyderabad
: Synthesis of Natural product-inspired Macrocyclic Architectures and Hybrid Latrunculins.
PhD degree awarded, University of Hyderabad, Dec 2014.
: Srinivas Chamakuri
: Going to Join Professor Damian Young, Baylor College of Medicine, USA
(June 2015)
:
Synthesis of Amino-indoline Based Macrocycles and Treprostinil Inspired Hybrid Compounds.
PhD degree awarded, University of Hyderabad, Jan 2015.
: Ravikumar Jimmidi
: GVKBio Hyderabad
: A Divergent Approach to Benzofuran-inspired, Macrocycles and Eribulin Fragment-based Hybrid Compounds.
PhD degree awarded, University of Hyderabad, Feb 2015.
: Shiva Krishna Reddy Guduru
: Going to Join Professor Damian Young, Baylor College of Medicine, USA
(July 2015)
:
A Divergent Approach to Tetrahydroquinoline-Based Macrocycles and Rapamycin Fragment-Derived Hybrid Molecules.
PhD degree awarded, University of Hyderabad, March 2015.
: Bhanudas Dasari
: Waiting for PhD thesis defence
: Synthesis of Carbohydrate-based Macrocycles and Epothilone Fragment-derived Hybrid Molecules
PhD thesis submitted, University of Hyderabad, Dec 2014.
Ongoing PhD Students
: Srinivas Jogula
: Jan 2011
:
1. C-Glyco-based Macrocyclic Diversity (published in Eur. J. Org. Chem. 2014).
2. Stereoselective Synthesis of Ansamycin-based Hybrid Macrocycles.
: Saidulu Konda
: Jan 2011
:
Stereoselective Synthesis of Western Furan Ring Fragment and Related Macrocyclic Compounds.
: Mahender Khatravath
: Jan 2011
:
Stereoselective Synthesis of the Sub-structures of Eribulin and Derived Macrocycles
: Naveen Kumar Mallurwar
: Jan 2011
:
Stereoselective Synthesis of Fragments of Eribulin and Derived Hybrid Macrocycles
: Jagan Gaddam
: Jan 2011
:
Stereoselective Synthesis of Neopeltolide Inspired Macrocyclic Compounds
Past Group Members- Post-doctoral Fellows and Technical Officers
Ms. U. Wronska, 1993-94, Canadian Patent Office, Ottawa
Dr. Sho-Nong Wang, 1995, Sussex Research Labs, Ottawa
Mr. Guy Boisvert, 1993-95, Technical Officer, Waters
Mr. Sylvain Dion, 1996-97, Technical Officer, CHUL, Quebec City
Dr. Suoding Cao, 1996, GlycoDesign, Toronto
Dr. George Shimizu, 1996, Professor, Dept of Chem, Univ of Calgary
Dr. Francois Maltais, 1996-97, Vertex Pharmaceuticals, USA
Dr. Johanne Roby, 1997-98, CEGEP Teacher, Sherbrooke
Dr. Robert Ben, 1996-98, Professor, Dept of Chem, Ottawa
Dr. Huiping Qin, 1997-99, Software Eng, Sprint USA
Dr. Kristina Kutterer, 1997-99, Wyeth Ayerst, NY, USA
Dr. N. Venugopal Rao, 1998-00, Johnson Matthey Pharmaceuticals, USA
Dr. Angela Barkley, 1998-01, Johnson Matthey Pharmaceuticals, USA
Dr. Wei He, 1999-00, Naeja Pharmaceuticals, Alberta
Dr. Yifa Zhou, 2000-01, Chiron Cooperation, Singapore
Dr. Gautam Panda, 2000-01, Research Scientist, CDRI, Lucknow, India
Dr. Karla Randell, 2000-01, Canadian Patent Office, Ottawa
Dr. Myung-Gi Baek, 1999-01, BioMira, Edmonton, Alberta
Dr. Doug Chou, 2000-02, Cardiome Pharma, Vancouver
Dr. Bugga Sarma, 2000-02, SaiAdvantium Laboratories Ltd, India
Dr. Suzanne Hof, 2000-02, Patent Law Company, Ottawa
Dr. Zai-Xin Chen, 2001-02, Jiangsu Yabang Pharma, China
Dr. Reni Joseph, 2001-03, MDS Pharma, Montreal (moved to USA)
Dr. Patricia Durieux, 2002-03, Syngenta Crop Protection AG, Switzerland
Dr. Samuel Couve-Bonnaire, 2002-03, Professor, Rouen, France
Dr. Chang-Qing Wei, 2001-03, PainCeptor Pharma, Ottawa
Dr. Majid Rastegar, 2002-04, PDF, Carleton University (presently with Health Canada)
Dr. Rohtash Kumar, 2003-04, Research Scientist, Pharmaceutical Company, Alberta
Dr. Nallareddy Babu, 2002-04, Research Scientist, Naeja Pharmaceuticals, Edmonton
Ms. Sophie Quevillon, 2003-04, Research Scientist, Health Canada
Dr. Zhonghong Gan, 2002-04, Research Scientist, Sussex Research Labs, Ottawa
Ms. Maya Sharma, 2003-05, PhD Student, Dept of Chem, University of Manitoba
Mr. Shahriar Khadem, 2001-05, Research Scientist, Health Canada, Ottawa
Dr. Utpal Sharma, Research Scientist, 2003-05, Naeja Pharmaceuticals, Edmonton
Dr. P. Thirupathi Reddy, 2003-06, Research Scientist, Pharmaceutical Company, Canada
Dr. Ayub Reayi, 2004-06, Canadian Patent Office, Ottawa
Dr. Deo Ntirampebura, 2005-06, PainCeptor Pharma, Ottawa
Dr. Stuti Srivastava, 2004-06, Research Scientist, Pharmaceutical Company, India
Dr. Ravi Naga Prasad, 2005-07, Research Scientist, Pharmaceutical Company, India
Mr. Michael L. Barnes, 1996-2007, SIMS, NRC
Dr. Michael Prakesch, 2004-07, Research Scientist, OICR Toronto
Jean-Louis Brochu, 2005-08, Research Scientist, Pharmaceutical Company, Canada
Dr. Rajamohan R. Poondra, 2006-08, Senior Research Scientist, Institute of Life Sciences (ILS), Hyderabad, India
Dr. Ramdas Borhade, 2008-2009, Research Scientist, Pharmaceutical Company, India
Dr. Nandyala Reddy, 2008-09, Post-Doctoral Fellow, McGill University
Dr Sreedhar Pamu, 2008-09, Post-Doctoral Fellow, McGill University
Dr. Lakshindra Chetia, 2008-09, Post-Doctoral Fellow, USA
Dr. Chinmoy Pramanik, 2008-09, Post-Doctoral Fellow, USA
Dr. Maragani Satyanarayana, 2008-09, Post-Doctoral Fellow, USA
Dr. Niranjan Kumar, 2007-09, Post-Doctoral Fellow, USA
Dr. Jyoti Prokash Nandy, 2004-09, Health Canada, Ottawa
Ms. Lam Pham, 2007-09
Rajnikanth, Research Trainee, 2011-12
Buddipally Ramesh Reddy, Research Trainee, 2011-13
Past Group Members- Graduate Students
Sophie Quevillon, Dept of Chem, Univ of Ottawa (Aug
2003), MS Thesis: Toward the Diversity-Oriented Synthesis of
Indoline-based Polycyclic Derivatives.
Kamani Ilangasinghe, Dept of Chem, Univ of Ottawa (Jan
2005), PhD Thesis: Stereocontrolled Diversity-Oriented Synthesis of
2H-Benzopyran-based Natural Product-like Polycyclic Derivatives.
Jean-Louis Brochu, Dept of Chem, Univ of Ottawa (Oct
2008), MS Thesis: A Modular Tandem Michael or Aza Michael Approach to
Obtain Indoline Alkaloid-like Polycyclic Architectures.
Lam Pham, Dept of Biochemistry, Microbiology and
Immunology, Univ of Ottawa (June 2010), MS Thesis: Natural
Product-Inspired Chemical Modulators of Protein-Protein Interactions:
The Pursuit of Three Lead Compounds.
Madhu Aeluri, PhD thesis awarded (December 2014),
University of Hyderabad. Thesis title: Synthesis of Natural
product-inspired Macrocyclic Architectures and Hybrid Latrunculins.
Joined as a scientist, GVKBio Hyderabad (one year assignment)
Srinivas Chamakuri, PhD thesis awarded (January 2015),
University of Hyderabad Thesis title: Synthesis of Amino-indoline Based
Macrocycles and Treprostinil Inspired Hybrid Compounds.
Ravi Kumar Jimmidi, PhD thesis awarded (Feb 2015),
University of Hyderabad. Thesis title: A Divergent Approach to
Benzofuran-inspired, Macrocycles and Eribulin Fragment-based Hybrid
Compounds. Joined as a scientist, GVKBio Hyderabad (one year
assignment)
Shiva Krishna Reddy Guduru, PhD thesis submitted (Mar
2015), University of Hyderabad Thesis title: A Divergent Approach to
Tetrahydroquinoline-Based Macrocycles and Rapamycin Fragment-Derived
Hybrid Molecules.
Bhanudas Dasari, PhD thesis submitted (Dec 2014),
University of Hyderabad Thesis title: Synthesis of Carbohydrate-based
Macrocycles and Epothilone Fragment-derived Hybrid Molecules.
Past Undergraduate Students
Mario Rios, Dept of Chem, Univ of Ottawa (2000-01), Hons
Thesis, A novel approach to chiral, polycyclic ring derivatives from
D-galactose.
Benoit Seguin, Dept of Chem, Univ of Ottawa (2000-01),
Hons Thesis, Toward the synthesis of dihydroindole-derived natural
product-like compounds.
Karim Mekhail, Dept of Chem, Univ of Ottawa (2001-02),
Hons Thesis, Toward enantioselective synthesis of highly functionalized
eight-membered ring natural product-like derivatives.
Paul Czechura, Dept of Chem, Univ of Ottawa (2001-02),
Hons Thesis, Towards an enantioselective approach to indole
alkaloid-like polycyclic derivatives.
Mathieu Parisien, Dept of Chem, Univ of Ottawa
(2002-03), Hons Thesis- A synthetic approach to indoline-derived
polycyclic derivatives having a β-amino acid functionality.
Marc Lafrance, Dept of Chem, Univ of Ottawa (2002-03),
Hons Thesis- Synthesis of benzofuran-derived natural product-like
tricyclic derivative.
Louis-Charles Campeau, Dept of Chem, Univ of Ottawa
(2002-03), Hons Thesis- Tetrahydroquinoline-derived β-amino acids as
novel scaffolds for diversity-oriented synthesis.
Daisy Laforce, Dept of Chem, Univ of Ottawa (2002-03),
Hons Thesis- Towards the synthesis of tetrahydroquinoline-based
polycyclic derivatives with medium size rings.
Charles Roy, Dept of Chem, Univ of Ottawa (2003-04),
Hons Thesis- Towards the synthesis of novel macrocyclic glycosamino
acids.
Juzer Kakal, Dept of Biochem, Univ of Ottawa (2003-04),
Hons Thesis- Towards the synthesis of medium size ring derivatives from
carbohydrates.
Hilda Antony, Dept of Chem, Univ of Ottawa (2003-04),
Hons Thesis- Tetrahydroaminoquinoline-derived β-amino acid and β- amino
alcohol as novel scaffolds.
Jean-Louis Brochu, Dept of Chem, Univ of Ottawa
(2003-04), Hons Thesis- A synthetic approach to indoline-derived
polycyclic derivatives.
Kassandra Lepack, Dept Chem and Pharmaceutical Sciences,
Univ of Ottawa, 2007-08, Hons Thesis- Natural product-inspired
chemical modulators of Bcl-2 family.
Monica Wirz, Dept Chem and Pharmaceutical Sciences, Univ
of Ottawa, 2007-08, Hons Thesis- The development of a novel
cycloaddition approach leading to benzofuran-derived polycyclic
architectures.
Sheila Michel, Dept Chem and Pharmaceutical Sciences,
Univ of Ottawa, 2007-08, Hons Thesis- Novel chemical probes of Bcl-2
and Mcl-1 for developing cell death modulators.
Asna Choudhry, Biochem Dept, Univ of Ottawa, 2007-08, Hons
Thesis – Natural product-inspired chemical modulators of focal adhesion
kinase (FAK) pathways.
February 17-19, 2014 • HICC, Hyderabad, India
Prof. Prvabhat Arya
Head, Organic & Medicinal
Chemistry Program,
Dr. Reddy's Institute vof Life Sciences
The challenges of small molecules as drug candidates continue to attract the debate of global bio-pharma R&D industry. Late stage failures and narrowing pipeline has empowered small and medium discovery R&D companies with opportunities. Scope for innovation is very high, considering the inefficiencies and success rates. So drug discovery significantly influence the performance of bio-pharma R&D. Drug Discovery conference of BioAsia identifies India as an opportunity for global bio-pharma R&D, while investigating key trends of the industry for the benefit of participants. BioAsia identifies drug discovery as an important discipline as an ongoing opportunity to track scientific developments and promote collaborations.
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Pharmacology and ToxicologyRaebareli, India
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