DR ANTHONY MELVIN CRASTO,WorldDrugTracker, helping millions, A 90 % paralysed man in action for you, I am suffering from transverse mylitis and bound to a wheel chair,With death on the horizon, This will not stop me, Gods call only..........
DR ANTHONY MELVIN CRASTO Ph.D ( ICT, Mumbai) , INDIA 29Yrs Exp. in the feld of Organic Chemistry,Working for GLENMARK PHARMA at Navi Mumbai, INDIA. Serving chemists around the world. Helping them with websites on Chemistry.Million hits on google, world acclamation from industry, academia, drug authorities for websites, blogs and educational contribution

Wednesday, 2 March 2016

Shahar Keinan, Chief Scientific Officer and Cofounder at Cloud Pharmaceuticals

Shahar Keinan

Shahar Keinan

Chief Scientific Officer and Cofounder at Cloud Pharmaceuticals

Background

Dr. Shahar Keinan, Ph.D., co-founded Cloud Pharmaceuticals, Inc., in 2009 and serves as its Chief Scientific Officer. Dr. Keinan has extensive experience in the field of computational and theoretical chemistry. She has been instrumental in the development of the novel Inverse Design technology since its inception at Duke University, and has pioneered the use of the Inverse Design algorithm to optimize electro-optical materials and protein inhibitors. She has published over 25 peer-reviewed research articles. She leads the development and deployment of Inverse Design and Protein Symphony. She oversees the technical staff of TeraDiscoveries. She serves as Director of Cloud Pharmaceuticals. She obtained a Ph.D. in theoretical chemistry and a B.S. in Chemistry from The Hebrew University of Jerusalem.
LINKS
http://www.cloudpharmaceuticals.com/dr-shahar-keinan.html
https://www.linkedin.com/in/shahar-keinan-9b729b1
https://www.facebook.com/shahar.keinan.5/about
 https://plus.google.com/104847823339870075169/about

Dr. Shahar Keinan

Picture
Shahar Keinan, Ph. D.
Chief Scientific Officer (CSO) and CofounderShahar Keinan is the Chief Scientific Officer and co-founder of Cloud Pharmaceuticals. She has over 20 years of extensive experience in the field of computational and theoretical chemistry. Shahar has received a Ph.D. in theoretical chemistry from The Hebrew University of Jerusalem and has numerous papers and presentations in the fields of in-silico drug design and discovery, as well as molecular materials design and computational methods development.Shahar has been instrumental in the development of the novel Quantum Molecular Design process since its inception at Duke University, and has pioneered the use of the Quantum Molecular Design algorithm to optimize electro-optical materials and protein inhibitors. Currently, she leads the development and deployment of Quantum Molecular Design and oversees the technical staff of Cloud Pharmaceuticals.esign and computational methods development.
Shahar has been instrumental in the development of the novel Quantum Molecular Design process since its inception at Duke University, and has pioneered the use of the Quantum Molecular Design algorithm to optimize electro-optical materials and protein inhibitors. Currently, she leads the development and deployment of Quantum Molecular Design and oversees the technical staff of Cloud Pharmaceuticals.

Experience



Chief Scientific Officer and Cofounder

Cloud Pharmaceuticals
January 2008 – Present (8 years 3 months)RTP, NC
Cloud Pharmaceuticals (previously TeraDiscoveries, Inc.) designs new drugs and drug candidates and accelerates the development process by implementing new, innovative cloud computing technology in place of traditional methods.
Cloud Pharmaceuticals
Cloud Pharmaceuticals


Post-Doctoral fellow

Duke University
January 2004 – September 2011 (7 years 9 months)
Inter-protein electron transfer
Inverse design of NLO materials
Inverse design of drugs
With Prof. Weitao Yang and Prof. David N. Beratan
Preformed theoretical design of organic molecules with high non-linear optical response (hyperpolarizability) properties, using inverse design methodologies.
Designed quinoid inhibitors for Cdc25 phosphatase, with potential as cancer drugs.


Post-Doctoral Fellow

Northwestern University
2001 – 2004 (3 years)Evanston, IL
Design of NLO materials
Theoretical Chemistry group
With Prof. Mark Ratner
Collaborating with the experimental group of Prof. Tobin Marks
Department of Chemistry

Education



The Hebrew University

PhD, Chemistry
1994 – 2000
Advisor: Prof. David Avnir
Thesis title: “The Applications of the Continuous Symmetry and Chirality Measures”

 

Honors & Awards

2002 The Junior Researcher Award from the Lise-Meitner Minerva Center, Israel.
2001 The R. Levine Prize of the Israeli Chemical Society for outstanding chemistry graduate.
1994 The Kenet Prize for Educational Merit in Undergraduate studies.

Shahar Keinan, PhD, Postdoc 2004-2011
CEO and founder Cloud Pharmaceuticals Compan

CSO Shahar Keinan and BOD Lex Van Der Ploeg at Look for at these events
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Saturday, 27 February 2016

Vidya Avasare




Dr. ( Mrs)  Vidya D Avasare

Associate Professor at Sir Parashurambahu College, Pune

 डॉ.विद्या

She loves teaching and doing science.......it is her passion,  hobby and everything


Links

 https://www.facebook.com/vidya.avasare
 https://in.linkedin.com/in/vidya-avasare-5a43ba29
 https://www.researchgate.net/profile/Vidya_Avasare/info
 http://oasis.csir.res.in/pidcv/OSDD_PI_DCV_56.pdf
 vidya avasare

@42e5ddc110aa437

 https://plus.google.com/112455079275578184081/about

Education






Publications



Pradeep Mathur, Vidya D. Avasare, Shaikh M. Mobin
Journal: Journal of Cluster Science - J CLUST SCI , vol. 20, no. 2, pp. 399-415, 2009
Pradeep Mathur, Vidya D. Avasare, Shaikh M. Mobin
Journal: Tetrahedron , vol. 64, no. 37, pp. 8943-8946, 2008
Pradeep Mathur, Saurav Chatterjee, Vidya D. Avasare
Journal: Cheminform , vol. 39, no. 14, 2008
Pradeep Mathur, Saurav Chatterjee, Vidya D. Avasare
Journal: Advances in Organometallic Chemistry - ADVAN ORGANOMETAL CHEM , vol. 55, pp. 201-277, 2007
Pradeep Mathur, Vidya D. Avasare, Abhijit K. Ghosh, Shaikh M. Mobin
Journal: Journal of Organometallic Chemistry - J ORGANOMET CHEM , vol. 689, no. 7, pp. 1325-1327, 2004




P. Mathur
    Professor
    Department of Chemistry
    Indian Institute of Technology Bombay



Memberships
Member of Royal Society of Chemistry and Executive Council Member
of RSC-WIS
Member of Indian National Congress
Member of Marathi Vigyan Parishad
 Clips
 
The RSC’s West India Local Section held their first student chemistry outreach event on the 20th October 2012 at KTHM College Nashik, entitled: ‘Opportunities and Advances in Chemical Sciences’. Nearly 200 post-graduate students and teachers, from Nashik and nearby PG Science Colleges, participated in the event – a clear success! http://my.rsc.org/blogs/80/1084

Mrs Nirmala Pawar and Dr. Vidya Avasare introduced the audience to the Vision and Mission of RSC, which was followed by a key note address by Professor Goutam Lahiri, IITB, on ‘Opportunities and Advances in Chemical Sciences’.

The scientific sessions were contributed to by eminent professors and scientists from the diverse fields of organic, inorganic, physical and materials chemistry. Some inspiring talks were delivered:
  • “Redox Non-Innocent Assembly: Leading to Alternate Electronic Structures”. Professor Goutam Lahiri,  IIT Bombay
  • “Conducting Plastics: Fundamental and Applications”. Dr. M. Jayakannan, IISER-Pune
  • “Organic Synthesis: Myths and Facts”. Dr. Rodney Fernandes, IIT Bombay
  • “Tiny Twinkling Specks of Sand”.  Professor Anindya Datta, IIT Bombay
  • “Stereoselective Synthesis and Applications of Donor Acceptor Cyclopropanes (DACs)”.  Dr. Santosh Gharpure, IIT Bombay
  • “Implications of Macromers in Biology”. Dr. Jayant Khandare, Piramal Health Sciences Pvt. Ltd. Goregaon, Mumbai  
                   

Professor Vidya Avasare MRSC planned and coordinated the event diligently, taking the chemistry outreach of the RSC’s West India Local Section beyond major cities. Dr. Raghunath Toche, convener of the conference from KTHM College, Nashik, expressed gratitude towards the RSC’S West India Local Section for organising the event.
 



Room-temperature synthesis of TiO2 nanospheres and their solar driven photoelectrochemical hydrogen production


Article in International Journal of Energy Research 39(12) · August 2015 
DOI: 10.1002/er.3372
Highly monodisperse and crystalline anatase phase TiO2 nanospheres have been synthesized at room temperature from organometallic precursor, titanocene dichloride and sodium azide. The photoelectrochemical (PEC) water splitting performance on the TiO2 nanospheres was studied under illumination of AM 1.5G. The optimized photocurrent density and photoconversion efficiency of TiO2 NSPs were observed ~0.95 mA cm−2 at 1.23 V and 0.69%, respectively. The transient photocurrent response measurements on the TiO2 NSPs during repeated ON/OFF visible light illumination cycles at 1.23 V vs RHE show that both samples exhibited fast and reproducible photocurrent responses. The TiO2 NSPs show excellent catalytic stability, and significant dark current was not observed even at high potentials (2.0 V vs RHE).











Iron pentacarbonyl assisted photochemical route to 2,5-and 2,6-divinyl-substituted 1,4-benzoquinones from 1-ene-3-ynes

Article in Tetrahedron 64(37):8943-8946 · 
DOI: 10.1016/j.tet.2008.06.059Photochem. reaction between the enynes, (Z)-1-methoxybut-1-ene-3-yne or isopropenyl acetylene, with CO in presence of Fe(CO)5 yields the 2,6- and 2,5-divinyl-substituted 1,4-benzoquinones: 2,6-bis{(Z)-2-methoxyvinyl}-1,4-benzoquinone (42%) and 2,5-bis{(Z)-2-methoxyvinyl}-1,4-benzoquinone (31.5%) from (Z)-1-methoxybut-1-ene-3-yne, and [{η2,η2:2,6-di(prop-1-en-2-yl)-1,4-benzoquinone}tricarbonyliron] (45%) and [{η2,η2:2,5-di(prop-1-en-2-yl)-1,4-benzoquinone}tricarbonyliron] (65%) from isopropenyl acetylene








 

 







Sir Parshurambhau College  
College in Pune, India
Sir Parshurambhau College is a college in Pune, Maharashtra, India. Established in 1916, it is governed by the Shikshan Prasarak Mandali education society. Wikipedia
Address: Tilak Road, Sadashiv Peth, Pune, Maharashtra 411030
 Map of Sir Parashurambhau College

 

 S P College
 Title for slide 2


 Title for slide 4
 Title for slide 1
 Title for slide 3

 
 
 
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Wednesday, 17 February 2016

Masoumeh Divar

Masoumeh Divar.


Masoumeh Divar

Research Associate at Pharmaceutical Sciences Research Center, Shiraz university of Medical Sciences
 

LINKS
 https://ir.linkedin.com/in/masoumeh-divar-15183381
 https://www.researchgate.net/profile/Masoumeh_Divar



Summary

I'm passionate about pharmaceutical sciences, dendrimer synthesis and organic chemistry and also I'm perfectionist in modern spectroscopic techniques, chromatographic techniques, Nuclear Magnetic Resonance Spectroscopy (NMR), Fourier Transform Infrared Spectroscopy (FT-IR), UV-Vis Spectroscopy, Matrix-assisted laser desorption/ionization (MALDI-TOF), Gel permeation chromatography (GPC), High-Performance Liquid Chromatography (HPLC), and Visible and Ultraviolet Spectroscopy. I'm looking forward to applying organic synthesis and characterization technique in post doc position.




Experience




research assistant

Pharmaceutical Science Research center, Shiraz University of Medical Sciences.
– Present (1 year 1 month)Shiraz
I've desined and done some pharmacutical projects in this center and also I designed projects for undergraduate pharmacy students and mentored them during thair projects.
(Open)4 projects



PhD in organic chemistry ( teaching assistant)

Shiraz university
– (4 years 1 month)Shiraz/ Iran
Leading undergraduate student in organic chemistry lab I & II. I also taught general chemistry I & II and organic chemistry I & II.



Visiting Scholar

University of Pennsylvania
– (7 months)New Philadelphia, Pennsylvania
I worked on peptide dendrimer synthesis



Master of Science ( teaching assistant)

Shiraz university
– (3 years 1 month)

Education




Shiraz University

Doctor of Philosophy (PhD), organic chemistry, 19


Shiraz University

Master of Science (M.S.), Organic Chemistry



Islamic Azad University of Firoozabad

Bachelor of Science (B.S.), Applied Chemistry

Publications




Magnetic nanoparticles-supported tungstic acid (MNP-TA): an efficient magnetic recyclable catalyst for the one-pot synthesis of spirooxindoles in water

RSC Advances
May 2015This paper reports the preparation, characterization and catalytic application of a novel, magnetically separable catalyst consisting of tungstic acid supported on silica coated magnetic nanoparticles. To obtain this new catalyst system, first, (3-chloropropyl)triethoxysilane was reacted with silica coated magnetic nanoparticles to generate a 3-chloropropyl magnetic nanoparticle (3-CPMNP)



Nucleosides as reagents in multicomponent reactions: one-pot synthesis of heterocyclic nucleoside analogues incorporating pyrimidine-fused rings

Tetrahedron Letters
2013In this study, a general and efficient protocol for the synthesis of new heterocyclic nucleoside analogues (HNAs), using a four-component coupling reaction of nucleosides, aldehydes, barbituric acid/2-thiobarbituric acid, or dimedone is described. The synthesized HNAs contain a pyrimidine-fused heterocycle coupled to the nucleoside via a C–N linkage. The nucleosides served as amine components and...

Synthesis of α‑Aminonitriles with Benzimidazolic and Theophyllinic Backbones Using the Strecker Reaction

JOC
August 26, 2013An example of the application of the Strecker reaction in the synthesis of a new class of α-aminonitriles with benzimidazole and theophylline backbones has been developed. For the synthesis of these compounds, first 4-hydroxybenzaldehyde was reacted with 1,3- and 1,5-
dibromides/epibromohydrin to produce the corresponding bromo-substituted aldehydes. Then, benzimidazole/theophyl-line was reacted..



Silica sulfuric acid (SSA) as a highly efficient heterogeneous catalyst for persilylation of purine and pyrimidine nucleobases and other N-heterocycles using HMDS

Phosphorus, Sulfur, and Silicon and the Related Elements
2010
Purine and pyrimidine nucleobases and other N-heterocycles have been silylated with HMDS in excellent yields in the presence of a catalytic amount of silica sulfuric acid (SSA), as a heterogeneous catalyst. SSA utilizes shorter reaction time and higher yields of silylated nucleobases. SSA is reusable for several times without decrease in reactivity and the yield of silylated
adducts




Honors & Awards

Iran Nanotechnology Initiative Council Incentive Support

Doctor of Philosophy Admission


Ranke first in the Entrance Exam for Ph.D. in Organic Chemistry in Shiraz University

One of the Highest Ranked Ph.D. Student. G.P.A. (GPA 3.76)


Projects




Synthesis and Evaluation of Some New Quinazoline Derivatives as Antifungal Agents


a variety of quinazolinone derivatives were successfully synthesized, via a three-component condensation reaction between anthranilic acid, anhydrides and primery amines. The synthesized compounds will be evaluated for their antifungal activity.



Antibacterial and Antifungal Effect of Some new Heterocyclic Nucleoside Analogues Incorporating Quinoline and Pyrimidine-fused Rings


In summary, this study describes an efficient one-pot access to a new class of heterocyclic nucleoside analogues having quinoline or pyrimidine-fused ring in its structural framework. To obtain these categories of heterocyclic compounds, nucleoside acts as amine component and remind in the structure of obtained molecule via a C-N linkage. This protocol is general for a wide range of nucleosides,...more



Antibacterial and Antifungal Effect of Some new Isatin derivatives including Semicarbazone & Thiosemicarbazone




Anticonvalsunt Effect of Some new Isatin derivatives including Semicarbazone & Thiosemicarbazone









Phosphorus, Sulfur, and Silicon and the Related Elements

Volume 185, Issue 9, 2010

Silica Sulfuric Acid (SSA) as a Highly Efficient Heterogeneous Catalyst for Persilylation of Purine and Pyrimidine Nucleobases and Other N-Heterocycles Using Hmds
Original Articles

Silica Sulfuric Acid (SSA) as a Highly Efficient Heterogeneous Catalyst for Persilylation of Purine and Pyrimidine Nucleobases and Other N-Heterocycles Using Hmds

DOI:
10.1080/10426500903383952
Mohammad Navid Soltani Rada, Ali Khalafi-Nezhadb, Masoumeh Divarb & Somayeh Behrouzb
pages 1943-1954


  • a Department of Chemistry , Faculty of Basic Sciences, Shiraz University of Technology , Shiraz, Iran
  • b Department of Chemistry , College of Sciences, Shiraz University , Shiraz, Iran
Purine and pyrimidine nucleobases and other N-heterocycles have been silylated with HMDS in excellent yields in the presence of a catalytic amount of silica sulfuric acid (SSA) as a heterogeneous catalyst. SSA utilizes a shorter reaction time and higher yields of silylated nucleobases. SSA is reusable for several times without a decrease in reactivity or yield of silylated adducts.









Synthesis of α-Aminonitriles with Benzimidazolic and Theophyllinic Backbones Using the Strecker Reaction

Department of Chemistry, College of Sciences, Shiraz University, Shiraz 71454, Iran
J. Org. Chem., 2013, 78 (21), pp 10902–10908
DOI: 10.1021/jo401890g
Publication Date (Web): October 3, 2013
Copyright © 2013 American Chemical Society
*E-mail: khalafi@chem.susc.ac.ir (A.K.-N.)., *E-mail: panahi@shirazu.ac.ir (F.P.). Fax: +98(711)2280926.

Abstract

Abstract Image
An example of the application of the Strecker reaction in the synthesis of a new class of α-aminonitriles with benzimidazole and theophylline backbones has been developed. For the synthesis of these compounds, first 4-hydroxybenzaldehyde was reacted with 1,3- and 1,5-dibromides/epibromohydrin to produce the corresponding bromo-substituted aldehydes. Then, benzimidazole/theophylline was reacted with the latter to generate the related benzimidazolic/theophyllinic aldehydes. Finally, the Strecker reactions of the synthetic benzimidazolic and theophyllinic aldehydes with different amines afforded the target products.
 http://pubs.acs.org/doi/abs/10.1021/jo401890g




Paper

Magnetic nanoparticles-supported tungstic acid (MNP-TA): an efficient magnetic recyclable catalyst for the one-pot synthesis of spirooxindoles in water

*
Corresponding authors
a
Department of Chemistry, College of Sciences, Shiraz University, Shiraz 71454, Iran
E-mail: khalafi@chem.susc.ac.ir, panahi@shirazu.ac.ir
Fax: +98 711 2280926
Tel: +98-7116137163
RSC Adv., 2015,5, 2223-2230

DOI: 10.1039/C4RA12976H
http://pubs.rsc.org/en/Content/ArticleLanding/2015/RA/C4RA12976H#!divAbstract
Received 23 Oct 2014, Accepted 19 Nov 2014
First published online 19 Nov 2014
This paper reports the preparation, characterization and catalytic application of a novel, magnetically separable catalyst consisting of tungstic acid supported on silica coated magnetic nanoparticles. To obtain this new catalyst system, first, (3-chloropropyl)triethoxysilane was reacted with silica coated magnetic nanoparticles to generate a 3-chloropropyl magnetic nanoparticle (3-CPMNP) substrate. Subsequently, the addition of sodium tungstate to 3-CPMNP resulted in the stabilization of tungstic acid species on the surface of the magnetic nanoparticles (MNP-TA). The synthesized catalyst was characterized using some different microscopic and spectroscopic techniques such as X-ray powder diffraction (XRD), transmission electron microscopy (TEM), scanning electron microscopy (SEM), and FT-IR spectroscopy. The catalyst nanoparticles were obtained with near spherical morphology and an average size of ∼45 nm. The W content of the catalyst was determined by ICP analysis to be 82.5 ppm (82.5 mg L−1), which was equal to 8.25% w/w (0.45 mmol g−1). The catalyst was successfully used for the one-pot synthesis of spirooxindoles via the multicomponent reaction of isatins and dicarbonyl compounds in water, which was used as a green solvent. The results revealed that this new catalyst showed high catalytic activity in this protocol and that it can be reused at least 5 times without any change in its catalytic activity.


Graphical abstract: Magnetic nanoparticles-supported tungstic acid (MNP-TA): an efficient magnetic recyclable catalyst for the one-pot synthesis of spirooxindoles in water
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