Irina Robu
Scientist with Experience in Stem Cell, Bioreactors and Biomaterials
- Department of Chemical Engineering and Materials ScienceDetroit, Michigan, United States
Energetic, enthusiastic scientist - chemical engineering, bioengineering of stem cells, biomaterials; photographer, traveler....
Linkedin, irinarobu
Email, irina.robu@gmail.com
GTalk, irina.robu@gmail.com
Skype, irinarobu_phd
Home Phone, 317-222-1022
Irina Robu (@irirobu) | Twitter
https://twitter.com/irirobu
https://www.facebook.com/public/Irina-Robu
Summary
Dynamic, resourceful and focused professional seeking employment in Pharma/Biomedical Devices Industry.
Specialties:
Cardiovascular Tissue Engineering ,Biomaterials, Bioreactor Development
and Culture, Stem Cells, Biochemical Assays, Primary, Stem Cell and
Tissue Cell Culture, Biofilms,Segmental Bone Defects, Process
Development, Process Research.Additional specialties: Chemical Engineering, Chemistry, Process Design and Process Control
Experience
Patent Analyst - Chemistry and Biotechnology
Landon IP
Performed
Evidence-of-Use studies by analyzing chemical, biochemical or
biochemical engineering products currently used in the market that may
be infringing on a patent of interest.
Performed qualitative analysis of patents and patent portfolios from, scientific, technical and business perspective.
Analyzed biomedical/chemical and biomedical device related databases (NCBI, PUB Med), IEEE journals,dissertations, thesis and other technical documentation for relevant prior art.
Performed qualitative analysis of patents and patent portfolios from, scientific, technical and business perspective.
Analyzed biomedical/chemical and biomedical device related databases (NCBI, PUB Med), IEEE journals,dissertations, thesis and other technical documentation for relevant prior art.
Postdoctoral Research Associate
Indiana University- Purdue University Indianapolis
Designed
and executed experiments involving mesenchymal stem cell and
endometrial culture isolation, expansion,
differentiation,characterization and identification.
Explored the osteogenic differentiation potential of MSC and endometrial stem cells to test their feasibility for bone tissue engineering applications.
Carried out in-vitro cell studies to assess osteogenic differentiation of human mesenchymal stem cells on type-II collagen sheets.
Conducted implant studies to check the effects of 3D cylindrical SLS scaffolds on bone formation in rats.
Analyzed the 3D cylindrical bioglass scaffolds pre-implantation using a) FTIR, XRD and SEM to assess their amorphousity, chemical bonding, composition and surface morphology of the scaffold and using MTS to assess their mechanical stability, b) histology to assess the presence of mineralized calluses bridging the gap of the segmental bone defects and c) verified the presence of tissue using micro-CT.
Explored the osteogenic differentiation potential of MSC and endometrial stem cells to test their feasibility for bone tissue engineering applications.
Carried out in-vitro cell studies to assess osteogenic differentiation of human mesenchymal stem cells on type-II collagen sheets.
Conducted implant studies to check the effects of 3D cylindrical SLS scaffolds on bone formation in rats.
Analyzed the 3D cylindrical bioglass scaffolds pre-implantation using a) FTIR, XRD and SEM to assess their amorphousity, chemical bonding, composition and surface morphology of the scaffold and using MTS to assess their mechanical stability, b) histology to assess the presence of mineralized calluses bridging the gap of the segmental bone defects and c) verified the presence of tissue using micro-CT.
Graduate Research Assistant in Tissue Engineering Laboratory
Wayne State University
Provided
technical training for undergraduate, master's and laboratory personnel
in using basic laboratory equipment and cell culture techniques.
Managed/mentored 4 undergraduate students for project completion and scientific skill development.
Identified optimal concentrations of polysaccharides and extra-cellular matrix substances to generate vascular graft scaffolds with desired mechanical properties.
Prepared composite (combination of non-porous and porous) and three-dimensional porous scaffolds for tissue engineered implants applications e.g. vascular graft.
Characterized the three dimensional porous scaffolds using mechanical and morphological methodologies such as XRD, SEM and Instron to assess their pore size, pore geometry, interconnectivity and % of void space and their efficiency for bioreactor culture.
Designed and assembled continuous and perfusion bioreactor cell culture system with external gas and medium oxygenation capabilities for conducting in vitro biomaterials – cell interaction studies.
Enhanced bioreactor performance by controlling the critical process parameters such as medium composition, flow and optimal scaffold seeding.
Presented research work at 13 national and international conferences.
Managed/mentored 4 undergraduate students for project completion and scientific skill development.
Identified optimal concentrations of polysaccharides and extra-cellular matrix substances to generate vascular graft scaffolds with desired mechanical properties.
Prepared composite (combination of non-porous and porous) and three-dimensional porous scaffolds for tissue engineered implants applications e.g. vascular graft.
Characterized the three dimensional porous scaffolds using mechanical and morphological methodologies such as XRD, SEM and Instron to assess their pore size, pore geometry, interconnectivity and % of void space and their efficiency for bioreactor culture.
Designed and assembled continuous and perfusion bioreactor cell culture system with external gas and medium oxygenation capabilities for conducting in vitro biomaterials – cell interaction studies.
Enhanced bioreactor performance by controlling the critical process parameters such as medium composition, flow and optimal scaffold seeding.
Presented research work at 13 national and international conferences.
Graduate Teaching Assistant
Wayne State University
Offered assistance with projects, homework, design project, HYSIS term project.
Presented fundamental concepts and test strategies, graded student assignment and exams for Thermodynamics (CHE 3300) and Transport Phenomena (CHE 3200), Product and Process Design (CHE 4200) and Process Dynamics and Simulation (CHE 4600), Chemical process Integration (CHE 4800) and Material and Mass Balances (CHE 2800).
Presented fundamental concepts and test strategies, graded student assignment and exams for Thermodynamics (CHE 3300) and Transport Phenomena (CHE 3200), Product and Process Design (CHE 4200) and Process Dynamics and Simulation (CHE 4600), Chemical process Integration (CHE 4800) and Material and Mass Balances (CHE 2800).
Graduate Research Assistant
Wayne State University
Prepared
and evaluated large density gradient experiments with compressible
supercritical CO2 and calibrated single ray path inhomogeneous
supercritical CO2.
Research Engineer
Detroit Edisson- Warren Service Center
Conducted plant surveys of chemical usage for chemical consumption database and cost savings analysis.
Performed routine experiments, analysis and calculations for internal reports.
Performed routine experiments, analysis and calculations for internal reports.
Volunteer Experience & Causes
Expert, Author and Writer
Leaders in Pharmaceutical Business Intelligence
June 2014Science and Technology
Research Categories:
•Biomaterials
•Bioreactors for Tissue Engineering
•Stem Cells for Regenerative Medicine
•Bone Disease and Musculoskeletal Disease
•Cell Therapy
•Medical Devices: Stents and Tools
•Technology Transfer: Biotech and Pharmaceutical
•Nanotechnology for Drug Delivery
•Biomaterials
•Bioreactors for Tissue Engineering
•Stem Cells for Regenerative Medicine
•Bone Disease and Musculoskeletal Disease
•Cell Therapy
•Medical Devices: Stents and Tools
•Technology Transfer: Biotech and Pharmaceutical
•Nanotechnology for Drug Delivery
Causes Irina cares about:
- Education
- Health
- Disaster and Humanitarian Relief
- Science and Technology
Courses
Wayne State University
- Tissue and Hybrid Systems
- Biomaterials
- Biocompatibility
- Advanced Kinetics and Reactor Design
- Advanced Thermodynamics
Education
Wayne State University
Doctoral Degree, Chemical Engineering
Dissertation Topic : Design of a polysaccharide tissue engineered vascular graft.
Research Area : Tissue Engineering, Biomaterials, Bioreactor, Mammalian Cell Culture
Activities and Societies: American Institute of Chemical Engineers, Biomedical Engineering Society,Society Canadian Bioengineering Society, Tissue Engineering and Regenerative Medicine Society,Biomaterials, Wayne State Engineering Society, Society of Women Engineers, Engineering Society of Detroit.
University of Windsor
Bachelor of Science, Chemistry
- Irina RobuWayne State University, Detroit, USAInstitution web page: http://www.eng.wayne.edu
Personal web page: http://www.tissue.eng.wayne.edu
Send emailBorn: 1977Interests: Tissue Engineered Blood Vessel, Endothelization, BiomechanicsDetails:Wayne State University,Detroit, Michigan, USA
Doctoral degree in Chemical Engineering with minor in Biomedical Engineering. Thesis interest :design of a tissue engineered blood vessel for pediatric patients
Currently pursuing a PhD in Chemical Engineering with a minor in Biomedical Engineering
Expected in Sept 2010
Wayne State University,
Detroit, Michigan, USA
Masters of Science in Chemical Engineering
Graduated in December 2004
Wayne State University,
Detroit, Michigan, USA
Bachelor of Science in Chemical Engineering
Graduated in May 2003
University of Windsor, Windsor,Ontario,Canada
Bachelor of Science in Chemistry
Graduated in June 2000
Selected publications:
• Irina Robu and Erhard Rothe. Probes of supercritical CO2 by deflection of multiple beamlets. Journal of Flow Visualization and Image Processing, 2005.
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