.Chafiq Hamdouchi
Senior Research Advisor at Eli Lilly and Company
LINKS
Summary
Dr. Hamdouchi earned his bachelor’s degree and doctorate in organic chemistry from Louis Pasteur University, Strasbourg-France.
Following two postdoctoral fellowships, sponsored by the National Science Foundation-USA and Ministerio de Educación y Ciencia-Spain, he joined Eli Lilly and Company in 1995.
Throughout his 20 years of career at Lilly, he has contributed to a sustainable drug discovery portfolio from preclinical hypothesis to clinical proof-of-concept that spans the oncology, neuroscience and endocrinology therapeutic areas. He has led multidisciplinary (chemistry, pharmacology, ADMET, PK, medical) scientific teams in USA, Europe and Asia to deliver a number of compounds that achieved first human dose.
He is a co-inventor of six innovative molecules being pursued in clinical development for the treatment of Diabetes, Cancer and Neurodegenerative Diseases.
He has an extensive patent and publication record and deep experience in conducting drug discovery and development in Asia through effective partnership and mentorship.
Following two postdoctoral fellowships, sponsored by the National Science Foundation-USA and Ministerio de Educación y Ciencia-Spain, he joined Eli Lilly and Company in 1995.
Throughout his 20 years of career at Lilly, he has contributed to a sustainable drug discovery portfolio from preclinical hypothesis to clinical proof-of-concept that spans the oncology, neuroscience and endocrinology therapeutic areas. He has led multidisciplinary (chemistry, pharmacology, ADMET, PK, medical) scientific teams in USA, Europe and Asia to deliver a number of compounds that achieved first human dose.
He is a co-inventor of six innovative molecules being pursued in clinical development for the treatment of Diabetes, Cancer and Neurodegenerative Diseases.
He has an extensive patent and publication record and deep experience in conducting drug discovery and development in Asia through effective partnership and mentorship.
Experience
Senior Research Advisor
Research Advisor
Principal Research Scientist
Research Scientist
Senior Organic Chemist
Assistant Professor
Patents
Preparation of 1,2,3,4-tetrahydroquinoline derivative useful in the treatment of diabetes(Link)
United States WO 2013025424 A1
Issued February 21, 2013Preparation of spiropiperidine derivatives for use as antidiabetic agents(Link)
United States WO 2011066183 A1
Issued June 3, 2011Spiropiperidine derivatives as GPR40 agonists and their preparation and use for the treatment of diabetes(Link)
United States WO 2011046851 A1
Issued April 21, 2011Thiazolylpyrazolopyrimidines as CRF1 receptor antagonists and their preparation, pharmaceutical compositions and use in the treatment of diseases(Link)
United States WO 2008036579 A1
Issued May 27, 2008Preparation of thiophene pyrazolopyrimidine compounds as corticotropin releasing factor 1 (CRF1) receptor antagonists(Link)
United States WO 2008036541 A1
Issued March 27, 2008Preparation of imidazo[1,2-b]pyridazine compounds as corticotropin releasing factor 1 receptor antagonists for treating psychiatric and neurol. diseases(Link)
United States WO 2006107784 A1
Issued October 12, 2006Preparation of imidazo[1,2-b]pyridazine compounds as corticotropin releasing factor 1 receptor antagonists for treating psychiatric and neurol. diseases(Link)
United States WO 2006102194 A1
Issued 2006Preparation of imidazo-pyridine derivatives as p38 kinase inhibitors(Link)
United States WO 2005075478 A1
Issued August 18, 2005Preparation of benzimidazoles and benzothiazoles as inhibitors of p-38 map kinase for treating metastasis or rheumatoid arthritis(Link)
United States WO 2004014900 A1
Issued February 19, 2004Anti-viral imidazo[1,2-a]pyridine derivatives and their pharmaceutical formulations and use(Link)
United States WO 9959587 A1
Issued November 25, 1999Spirocyclic C-glycosides
United States US19990342073
Filed 1999Preparation of phenyl-triazolo-pyridine compounds as activators of GPR-40(Link)
United States WO 2015105786 A1
Issued May 15, 2015Preparation of isopropyl triazolopyridine compounds for treating diabetes(Link)
United States WO 2015105779 A1
Issued January 16, 2015Preparation of novel triazolo-pyridine compounds for treating diabetes(Link)
United States WO 2015088868 A1
Issued June 18, 2015Education
Florida State University
National Science Foundation (NSF) Postdoctoral Fellowship, Organic Chemistry
Université Louis Pasteur (Strasbourg I)
Doctor of Philosophy (Ph.D.), Organic Chemistry
Université Louis Pasteur (Strasbourg I)
Master's Degree, Organic Chemistry
Université Louis Pasteur (Strasbourg I)
Bachelor's Degree, Chemistry
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