Mona Doshi Ph.D.
Postdoctoral Research Associate at College of Medicine, Univeristy of Central Florida
https://www.linkedin.com/in/mona-doshi-ph-d-47ab4591
https://www.researchgate.net/profile/Mona_Doshi
Experience
Postdoctoral Research Associate
University of Central Florida
Postdoctoral Research Fellow
University of Central Florida
Continuation of the project from Ph.D., while Mentoring the graduate and undergraduate students in the lab.
Research Assistant
University of Central Florida
As
a graduate research assistant while working towards my dissertation, I
setup the cell-culture facility in the lab and cultured a variety of
cell lines. The project included fabrication of polymer nanoparticles,
characterization of the nanoparticles, study the uptake of nanoparticles
in different cell lines and perform photodynamic therapy experiments on
these cell lines treated with the nanoparticles. This included confocal
fluorescence microscopy, intracellular spectroscopy, cell viability
assays etc.
- (Open)3 honors and awards
Ph.D. candidate
University of Central Florida
Fabrication
of composite conducting nanoparticles for targeted photodynamic
therapy. Single molecule and single particle spectroscopy. Intracellular
spectroscopy. Mentoring undergraduate student in lab.
Summary
In
the six years of my work towards dissertation I single-handedly managed
to setup the cell-culture facility and had hands on experience in
confocal fluorescence microscopy, cell viability assays, Atomic force
microscopy, Transmission electron microscopy, Single particle
spectroscopy.
Expertise:• Fabrication and characterization of conducting polymer/fullerene nanoparticles by Dynamic light scattering (DLS), Atomic force microscopy (AFM), Transmission electron microscopy (TEM), zeta potential, single particle spectroscopy (SPS).
• Cell culture: Cultured various cell lines such as OVCAR3, A549, MDA-MB-231, MCF7, MIA-PaCa2 and TE-71
• Cell viability assays: Hands on experience in MTT and MTS cell viability assays
• Confocal fluorescence microscopy: Built 3D images of single cells.
• Single particle/molecule spectroscopy and Intracellular spectroscopy: Hands on experience in characterization of conducting polymer at molecular level and conducting polymer nanoparticles, quantum dots, nanotubes at single particle level using an optical setup with Ar ion laser, diode lasers, Avalache photodiode (APD) for collecting fluorescence images and a CCD camera coupled with a spectrophotometer for acquiring single molecule/particle spectra.
• Lifetime imaging (FLIM): Measured fluorescence lifetime in chitosan nanoparticles and nanoparticle-treated plant samples using PicoQuant-Symphotime and 375 nm pulsed diode laser.
Patents
CANCER THERAPY VIA SELECTIVE UPTAKE OF SPECIALIZED NANOPARTICLES IN CANCER CELLS(Link)
United States 13/647,506
Issued May 23, 2013Publications
Development and Characterization of Conducting Polymer Nanoparticles for Photodynamic Therapy In Vitro(Link)
Photodiagnosis and Photodynamic Therapy
May 11, 2015Composite Conjugated Polymer/Fullerene Nanoparticles as Sensitizers in Photodynamic Therapy for Cancer(Link)
BioNanoscience, springer
December 7, 2013P3HT CHAIN MORPHOLOGY IN COMPOSITE P3HT/PCBM NANOPARTICLES STUDIED BY SINGLE PARTICLE FLUORESCENCE EXCITATION POLARIZATION SPECTROSCOPY(Link)
Biophysical Reviews and Letters, World Scientific
January 14, 2014Caveolae-Mediated Endocytosis of Conjugated Polymer Nanoparticles(Link)
Macromolecular Bioscience, Wiley
April 30, 2013An activatable multimodal/multifunctional nanoprobe for direct imaging of intracellular drug delivery(Link)
Biomaterials, Elsevier
November 10, 2011Fluorescent composite tubes with pH-controlled shapes(Link)
Journal of Materials Chemistry, RSC
March 9, 2010Photodynamic Therapy with Blended Conducting Polymer/Fullerene Nanoparticle Photosensitizers
Journal of Visualized Experiments (JoVE)
In press
CdS:Mn/ZnS Qdot Biosensing Probe
In preparation
- Application of charge transfer and triplet photochemistry in conjugated conducting polymer/fullerene nanoparticles in curing cancer
Excited state processes (ESP)
June 2014
Abstract for poster presentation
American Chemical Society (ACS)
August 2014
Abstract for poster presentation
Composite conducting polymer materials: Structure-function relationships at the nanoscale
American Chemical Society (ACS)
2011
Abstract for poster presentation
- Redox-active conducting polymer nanoparticles for cell imaging and therapy
American Chemical Society (ACS)
2011
Abstract for poster presentation
- Education
University of central florida
Doctor of Philosophy (PhD), Nanotechnology
June 2014
Doshi Wins Poster Award at ESP2014
Mona Doshi won 2nd prize for her poster presentation at ESP2014 in Santa Fe. Mona is a member of Dr. Andre Gesquiere’s research group.
Mona's poster presentation, "Application of Charge Transfer and Triplet Photochemistry in conjugated conducting polymer/fullerene nanoparticles in Curing Cancer," featured research conducted with Dr. Gesquiere and Dr. Alicja Copik of UCF's Burnett School of Biomedical Sciences. Gesquiere is an Associate Professor with the NanoScience Technology Center and Department of Chemistry.
The Excited State Processes in Electronic and Bio Nanomaterials Conference focuses on fundamental photoinduced phenomena in various nanostructured materials.
Mona's poster presentation, "Application of Charge Transfer and Triplet Photochemistry in conjugated conducting polymer/fullerene nanoparticles in Curing Cancer," featured research conducted with Dr. Gesquiere and Dr. Alicja Copik of UCF's Burnett School of Biomedical Sciences. Gesquiere is an Associate Professor with the NanoScience Technology Center and Department of Chemistry.
The Excited State Processes in Electronic and Bio Nanomaterials Conference focuses on fundamental photoinduced phenomena in various nanostructured materials.
Andre J. Gesquiere, Ph.D.
Associate Professor, Nanoscience Technology Center & Department of Chemistry
Ph.D., University of Leuven, Belgium (2001)
Phone: 407-454-1317
Fax: 407-882-2819
E-mail: andre@ucf.edu
Link: Dr. Gesquiere's Laboratory
College of Medicine, Univeristy of Central Florida
University of Central Florida College of Medicine
College in Orlando, Florida
The
University of Central Florida College of Medicine is an academic
college of the University of Central Florida located in Orlando,
Florida, USA. The dean of the college is Deborah C. German, M.D. Wikipedia
Address: 6850 Lake Nona Blvd, Orlando, FL 32827, United States
/////Mona Doshi, Ph.D, Postdoctoral Research Associate, College of Medicine, Univeristy of Central Florida, usa
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