Peptide Design and Materials
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| Dr. Schneider received his Ph.D. in Organic Chemistry from Texas A&M University with Jeffery Kelly and then went on to the University of Pennsylvania School of Medicine, Department of Biochemistry and Biophysics where he was a George W. Raiziss Fellow with William DeGrado studying protein design. In 1999, he began his independent career at the University of Delaware as an assistant professor of Chemistry and Biochemistry and was promoted to associate and then full professor in 2009 with a secondary appointment in Materials Science and Engineering. He joined the NCI in 2010 as lab Chief of the newly established Chemical Biology Laboratory. He currently serves as Editor in Chief of Biopolymers-Peptide Science, the journal of the American Peptide Society. |
Research Summary
| The Schneider group designs and characterizes novel materials for use in tissue regenerative therapy, parenteral delivery of therapeutics, delivery of cells, and antibacterial therapy. We are particularly interested in peptide and protein-based hydrogel materials formed by self-assembly mechanisms. Our work spans molecular conception, materials synthesis, nano- and bulk mechanical materials characterization, cell-material interactions, biocompatibility, and assessment of performance efficacy. Our basic research establishes how material composition and structure influences material function, and lays the foundation to ultimately translate materials to the clinic. |
PublicationsPatents
1 - 5 of 88 results
Cancer cell surface induced peptide folding allows intracellular translocation of drug.
J+Control+Release. 209: 317-26, 2015. [Journal]
2) Medina Scott H, Li Sandra, Howard O M Zack, Dunlap Micah, Trivett Anna, Schneider Joel P, Oppenheim Joost J.
Enhanced immunostimulatory effects of DNA-encapsulated peptide hydrogels.
Biomaterials. 53: 545-53, 2015. [Journal]
3) Micklitsch C, Medina S, Yucel T, Nagy-Smith K, Pochan D, Schneider J.
Influence of hydrophobic face amino acids on the hydrogelation of β-hairpin peptide amphiphiles.
Macromolecules. 48: 1281-1288, 2015. [Journal]
4) Sathaye S, Mbi A, Sonmez C, Chen Y, Blair DL, Schneider JP, Pochan DJ.
Rheology of peptide- and protein-based physical hydrogels: Are everyday measurements just scratching the surface?.
Wiley Interdiscip Rev Nanomed Nanobiotechnol. 7: 34-68, 2015. [Journal]
5) Schneider JP.
Another year behind us.
Biopolymers. 102: vii, 2014. [Journal]
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