Publications
CoMFA and CoMSIA studies on C-aryl glucoside SGLT2 inhibitors as potential anti-diabetic agents(Link)
Taylor and Francis online SAR and QSAR in Environmental Research (Impact factor: 1.68)
January 11, 2013
SGLT2
has become a target of therapeutic interest in diabetes research. CoMFA
and CoMSIA studies were performed on C-aryl glucoside SGLT2 inhibitors
(180 analogues) as potential anti-diabetic agents. Three different
alignment strategies were used for the compounds. The best CoMFA and
CoMSIA models were obtained by means of Distill rigid body alignment of
training and test sets, and found...more
CoMFA study of a series of N1-(substituted)aryl-2-(substituted)-5,7-dimethylpyrido[2,3- d]pyrimidin-4(3H)-one – Histamine H1-receptor antagonists(Link)
International Journal of Drug design and Discovery
April 2013CoMFA and CoMSIA Analysis of Protein Kinase B (PKBβ) Inhibitors Using Various Alignment Methods(Link)
Medicinal Chemistry Research, Springer (1.617 Impact Factor)
April 28, 2013Design of novel anaplastic lymphoma kinase (ALK) inhibitors based on predictive 3D QSAR models using different alignment strategies(Link)
Medicinal Chemistry Research, Springer (1.617 Impact Factor)
June 12, 20133D QSAR and HQSAR Analysis of Protein Kinase B (PKB/Akt) Inhibitors Using Various Alignment Methods
Arabian Journal of Chemistry, Elsevier publication. (Impact factor= 2.267)
2013Homology modeling, binding site identification and docking study of human β-arrestin: An adaptor protein involved in apoptosis
Medicinal Chemistry Research, Springer Publication
August 2013Design, synthesis and docking studies of some novel (R)-2-(4'-chlorophenyl)-3-(4'-nitrophenyl)-1,2,3,5-tetrahydrobenzo[4,5]imidazo[1,2-c]pyrimidin-4-ol derivatives as antitubercular agents
European Journal of Medicinal Chemistry (Impact factor: 3.49)
June 10, 2014
Novel imidazo [1,2-c] pyrimidin-4-ol derivatives are designed.
• Molecular docking study was carried out.
• Synthetic methodologies leading to targeted molecules have been reported.
• Molecular docking study was carried out.
• Synthetic methodologies leading to targeted molecules have been reported.
OTHER
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Nirma University · Institute of Pharmacy · Dr. Manjunath Ghate's group
Prof. Manjunath D Ghate
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