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Tuesday, 17 May 2016

Jenna Jeffrey





Jenna Jeffrey

Jenna Jeffrey was born in Springfield, OR. Although she didn�t exactly grow up on Evergreen Terrace, she still lived pretty close to the Simpson family. When she moved around the world she was devastated at the thought of losing friendships with Bart and Lisa, then she realized that she took the long way to move to Eugene and that Springfield was just across the river. She really didn�t want to take another chance at losing the Simpsons forever, so she stayed in Eugene for college at the University of Oregon, where her diet consisted mainly of pizza, ice cream, pizza flavored ice cream (but NOT ice cream flavored pizza) and the occasional Squishy from the local Kwik-E-Mart. Although that all sounds fattening, Jenna worked off all the calories with her favorite hobbies, running and soccer (aka running with somewhat of a purpose). While at Oregon, Jenna worked with Mike Haley, who looks an awful lot like a relative of the groundskeeper from her elementary school days. Jenna, however, has one regret from her youth. She was never able to learn to skateboard, even from the greatest of teachers, Bart.



Contact Information

Email: jennajeffrey at calmail dot berkeley dot edu 

Jenna Jeffrey
B.S. University of Oregon
Ph.D. University of California, Berkeley
Currently: Post-doc withProf. David MacMillan
Joined in: 2008



Research Interests


The synthesis of complex molecules, such as pharmaceuticals, relies on the development of efficient, scalable and operationally simple chemical transformations. Reactions that directly transform a C–H group into another functional group are particularly valuable tools for streamlining synthesis. My research is focused on the development of new methods and strategies for the synthesis of organic molecules. Two specific areas of current interest are (i) intramolecular carbon–nitrogen bond formation and (ii) carbon–carbon bond forming processes, which rely on the merger of organocatalysis and visible-light mediated photoredox catalysis.

Contact Info


NIH Postdoctoral Fellow
MacMillan Group
Department of Chemistry
Princeton University
Princeton, NJ 08544


Mobile: (541) 337-2755
Email: jjeffrey@princeton.edu


Publications

  
8. Jeffrey, J. L.; Terrett, J.; MacMillan, D.W.C., “O–H Hydrogen bonding promotes H-atom transfer from α C–H bonds for C-alkylation of alcohols,” Science 2015, 349, 1532–1536. (link)

  
7. Jeffrey, J. L.; Petronijevic, F. R.; MacMillan, D.W.C., “Selective Radical–Radical Cross-Couplings: Design of a Formal β-Mannich Reaction,” J. Am. Chem. Soc. 2015, 137, 8404–8407. (link)
  

  
6. Jeffrey, J. L.; Sarpong, R. “ Intramolecular C(sp)3–H amination,” Chem. Sci. 2013, 4, 4092–4106. (link)

5. Jeffrey, J. L.; Bartlett, E. S.; Sarpong, R. “Intramolecular C(sp)3–N Coupling by Oxidation of Benzylic C,N-Dianions,” Angew. Chem. Int. Ed. 2013, 52, 2194–2197. (link

         •  Featured in Synfacts, 9, 0533 (link).
  

  
4. Jeffrey, J. L.; Sarpong, R. “Chichibabin-Type Direct Alkylation of Pyridyl Alcohols with Alkyl Lithium Reagents,” Org. Lett. 2012, 14, 5400–5403. (link)

•  Featured in Synfacts, 9, 0194 (link).
  


3. Jeffrey, J. L.; Sarpong, R. “Concise Synthesis of Pauciflorol F Using a Larock Annulation,” Org. Lett. 2009, 11, 5450–5453. (link)
  
2. Jeffrey, J. L.; Sarpong, R. “An approach to the synthesis of dimeric resveratrol natural products via a palladium-catalyzed domino reaction,” Tetrahedron Lett. 2009, 50, 1969–1972. (link)
  
  
1. Jeffrey, J. L.McClintock, S. P.; Haley, M. M. “Synthesis of 1-substituted benzo[c]isoxazol-3(1H)-imines via tandem nitroso-ene/intramolecular cyclizations of 2-nitrosobenzonitrile,” J. Org. Chem. 2008, 73, 3288–3291. (link)
  

 



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