Johannes Kaschel
Research Scientist Medicinal Chemistry at AbbVie
Experience
Research Scientist Medicinal Chemistry
AbbVie
R&D:
- Chemistry in micelles (organic synthesis, catalysis)
- Neuroscience discovery
- Chemistry in micelles (organic synthesis, catalysis)
- Neuroscience discovery
Postdoc
UC Berkeley
Total synthesis of indole alkaloids (organic synthesis; total synthesis)
PHD Student
Georg-August-Universität Göttingen
Rearrangement reactions of donor-acceptor cyclopropanes (organic synthesis; methodology)
Honors & Awards
Postdoctoral fellowship
German Research Foundation (DFG)
Postdoctoral fellowship
German Research Foundation (DFG)
Publications
Ethynyl Benziodoxolone (EBX): Installing Alkynes the Reversed Way
Angew. Chem. Int. Ed. 2015, 54, 8876–8878
Donor-Substituted Nitrocyclopropanes: Immediate Ring-Enlargement to Cyclic Nitronates
Org. Lett. 2013, 15, 6098-6101
Rearrangements of Furan-, Thiophene- and N-Boc-Pyrrole-Derived Donor-Acceptor Cyclopropanes: Scope and Limitations
Eur. J. Org. Chem. 2013, 4539-4551
Donor-acceptor cyclopropanes with Lawesson’s and Woollins’ reagents: formation of bisthiophenes and unprecedented cage-like molecules
Chem. Commun. 2013, 49, 4403-4405
Symmetric and unsymmetric 3,3’-linked bispyrroles via ring-enlargement reactions of furan-derived donor-acceptor cyclopropanes
Org. Biomol. Chem. 2013, 11, 3494-3509
Domino Reactions of Donor-Acceptor-Substituted Cyclopropanes for the Synthesis of 3,3’-Linked Oligopyrroles and Pyrrolo[3,2-e]indoles
Angew. Chem. Int. Ed. 2012, 51, 11153-11156
One Pot - Two Phases: Iron-Catalyzed Cyclopropanation with in Situ Generated Diazomethane
Angew. Chem. Int. Ed. 2012, 51, 7085-7086
Total Synthesis of a-Linked Rha-Rha-Gal Undecaprenyl Diphosphate Found in Geobacillus stearothermophilus
Eur. J. Org. Chem. 2011, 6233-6239
From Furan to Molecular Stairs: Syntheses, Structural Properties and Theoretical Investigations of Oligocyclic Oligoacetals
Chem. Eur. J. 2010, 16, 11276-11288
anti-Oligoanellated THFMoieties: Synthesis via Push-Pull-Substituted Cyclopropanes
Org. Lett. 2009, 11, 2317-2320
Education
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| Johannes Kaschel |
| Ph.D.: U. of Goettingen |
| Currently: AbbVie |
Joined in: 2014 Johannes Kaschel Johannes grew up in Wolfenbuettel, Germany. For his studies of chemistry he moved to Goettingen, Germany, where he joined the group of Prof. D. B. Werz to investigate rearrangement reactions of donor-acceptor cyclopropanes. Since January 2014, Johannes has been a member of the Sarpong group with a Postdoctoral-Fellowship from the German Research Foundation (DFG) working on the total synthesis of indole alkaloids. Contact Information Email:jkaschel at berkeley dot edu |
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