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Thursday, 29 October 2015

Ghassan Abu Sheikha

Ghassan Abu Sheikha

Dean, Faculty of Pharmacy at 


Al-Zaytoonah University of Jordan

Department of Pharmaceutical Sciences
Telephone: + 962- 79- 5803339 Faculty of Pharmacy
FAX: +962- 6- 4291432
Al-Zaytoonah University of Jordan
E-Mail: gmabusheikha@yahoo.com
P.O. Box 130 Amman 11733 Jordan
(Tel 00962 64291511), e-mail: ztipc2015@zuj.edu.jo
Ghassan Abu Sheikha
Professor Ghassan M. Abu Shaikha obtained a Ph.D. degree in Medicinal Chemistry from University of Pisa- Italy , and a Bachelor degree in Pharmacy and Bachelor degree in Pharmaceutical Chemistry and Technology from University of Camerino - Italy . He started his professional life in Faculty of Pharmacy in University of Camerino – Italy as Assistant Research Professor, then as Assistant Professor of Medicinal Chemistry in Faculty of pharmacy in applied science university in Amman Jordan. He joined the academic team in the faculty of pharmacy in Al Zaytoonah university in 2005 as the dean of the faculty. where he taught various undergraduate and graduate courses and supervised around twenty five masters and Ph.D. students. Currently, he is a full professor of medicinal chemistry. His professional experience includes consultancy and advisory work for industry, research laboratories, and governmental institutions. He is a Member of American Association of Colleges of Pharmacy (AACP) since 2013 to present and an advisory member and Reviewer for Jordan Journal of Pharmaceutical Sciences

Ph.D in Medicinal Chemistry 1993 - 1997 Advisor: Professor Palmarisa Franchetti University of Pisa Italy B.S. Pharmacy 1992 - 1993 University of Camerino Italy
B.S. Pharmaceutical Chemistry and Technology 1985 - 1992 University of Camerino Italy
Visiting Research Scholar June 2013 - Aug 2013 College of Pharmacy and Pharmaceutical Sciences University of Toledo Toledo, OH
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Dean July 2011 - present Professor of Medicinal Chemistry Faculty of Pharmacy Al-Zaytoonah University Amman, Jordan
Dean Sept 2005 - July 2011, Associate Professor of Medicinal Chemistry Faculty of Pharmacy Al-Zaytoonah University Amman, Jordan
Associate Professor of Medicinal Chemistry Aug 2004 - Aug 2005 College of Pharmacy, King Khalid University Abha, Saudi Arabia
Associate Professor of Medicinal Chemistry Feb 2004 - Aug 2004 Faculty of Pharmacy Philadelphia University Amman, Jordan
Dean Feb 2003 - Oct 2003 Associate Professor of Medicinal Chemistry Faculty of Pharmacy Applied Science University Amman, Jordan
Dean Assistant Professor of Medicinal Chemistry July 2002 - Feb 2003 Faculty of Pharmacy Applied Science University Amman, Jordan
Deputy Dean Assistant Professor of Medicinal Chemistry Aug 2001 - Oct 2001 Faculty of Pharmacy Applied Science University Amman, Jordan
Assistant Professor of Medicinal Chemistry Sept 1998 - Feb 2003 Faculty of Pharmacy Applied Science University Amman, Jordan
Assistant Research Professor July1997– April 1998 Faculty of Pharmacy Camerino University Camerino, Italy
Summary of research interest
 Synthesis of anti-hyperlipidemia agents.  Synthesis of acyclic nucleoside phosphonates as anti- HIV-1 (antivirals).  Synthesis of nucleoside analogues as anti-cancer and antiviral.
Ghassan Abu Sheikha
1. FloHet-2013 Florida Heterocyclic and Synthetic Conference, March 3rd -March 6th, 2013, Gainesville, Florida, USA.
2. The Sixth International Conference of the Royal Medical Services, King Hussein Bin Talal Convention Center ,10-12 November 2012, Dead Sea, Jordan.
3. Faculties of Pharmacy at Al-Zaytoonah University of Jordan and The University of Toledo International Pharmaceutical Conference (ZTIPC 2012), 17-19 October 2012, Amman, Jordan.
Synthesis, structure, and antiproliferative activity of selenophenfurin, an inosine 5'-monophosphate dehydrogenase inhibitor analogue of selenazofurin
P Franchetti, L Cappellacci, GA Sheikha, HN Jayaram, VV Gurudutt, T Sint, ...
Journal of medicinal chemistry 40 (11), 1731-1737
Elaborate ligand-based pharmacophore exploration and QSAR analysis guide the synthesis of novel pyridinium-based potent β-secretase inhibitory leads
A Al-Nadaf, GA Sheikha, MO Taha
Bioorganic & medicinal chemistry 18 (9), 3088-3115
Synthesis and evaluation of the anti-HIV activity of aza and deaza analogs of isoddA and their phosphates as prodrugs
P Franchetti, L Cappellacci, M Grifantini, L Messini, GA Sheikha, AG Loi, ...
Journal of medicinal chemistry 37 (21), 3534-3541
Discovery of new cholesteryl ester transfer protein inhibitors via ligand-based pharmacophore modeling and QSAR analysis followed by synthetic exploration
RA Khalaf, GA Sheikha, Y Bustanji, MO Taha
European journal of medicinal chemistry 45 (4), 1598-1617
Pharmacophore and QSAR modeling of estrogen receptor β ligands and subsequent validation and in silico search for new hits
MO Taha, M Tarairah, H Zalloum, G Abu-Sheikha
Journal of Molecular Graphics and Modelling 28 (5), 383-400
A new acyclic heterodinucleotide active against human immunodeficiency virus and herpes simplex virus
P Franchetti, GA Sheikha, L Cappellacci, S Marchetti, M Grifantini, ...
Antiviral research 47 (3), 149-158
Synthesis and antiviral activity of 8-aza analogs of chiral [2-(phosphonomethoxy) propyl] guanines
P Franchetti, G Abu Sheikha, L Cappellacci, M Grifantini, A De Montis, ...
Journal of medicinal chemistry 38 (20), 4007-4013
A new class of acyclic nucleoside phosphonates: synthesis and biological activity of 9-{[(phosphonomethyl) aziridin-1-yl] methyl} guanine (pmamg) and analogues
GA Sheikha, P La Colla, AG Loi
Nucleosides, Nucleotides and Nucleic Acids 21 (10), 619-635
Preparation of mucoadhesive oral patches containing tetracycline hydrochloride and carvacrol for treatment of local mouth bacterial infections and candidiasis
RM Obaidat, A Bader, W Al-Rajab, GA Sheikha, AA Obaidat
Scientia pharmaceutica 79 (1), 197
8-Aza-analogues of PMEA and PMEG: Synthesis and in vitro anti-HIV activity
P Franchetti, GA Sheikha, L Cappellacci, L Messini, M Grifantini, AG Loi, ...
Nucleosides, Nucleotides & Nucleic Acids 13 (8), 1707-1719
Synthesis and Anti-Hyperlipidemic Evaluation of N‑(Benzoylphenyl)-5-fluoro-1H-indole-2-carboxamide Derivatives in Triton WR-1339-Induced Hyperlipidemic Rats
G Shattat, R Al-Qirim, Y Al-Hiari, GA Sheikha, T Al-Qirim, W El-Huneidi, ...
Molecules 15 (9), 5840-5849
Homology modeling of MCH1 receptor and validation by docking/scoring and protein-aligned CoMFA
A Abu-Hammad, WA Zalloum, H Zalloum, G Abu-Sheikha, MO Taha
European journal of medicinal chemistry 44 (6), 2583-2596
Acyclic nucleotides related to clitocine: Synthesis and anti-HIV activity
P Franchetti, L Cappellacci, GA Sheikha, M Grifantini, AG Loi, AD Montis, ...
Nucleosides, Nucleotides & Nucleic Acids 14 (3-5), 607-610
In Vivo Antihyperlipidemic Activity of a New Series of N‐(Benzoylphenyl) and N‐(Acetylphenyl)‐1‐benzofuran‐2‐carboxamides in Rats
T Al‐Qirim, G Shattat, K Sweidan, W El‐Huneidi, GA Sheikha, RA Khalaf, ...
Archiv der Pharmazie 345 (5), 401-406
Novel derivatives of 1, 3-dimethyl-5-methylenebarbituric acid
K Sweidan, Q Abu-Salem, A Al-Sheikh, GA Sheikha
Letters in Organic Chemistry 6 (8), 669-672
Pharmacological evaluation of novel indole-2-carboxamides as potent lipid-lowering agents in Triton-WR-1339-induced hyperlipidemic rats
T Al-Qirim, M Shahwan, G Shattat, Y Al-Hiari, GA Sheikha, S Zaidi
Zeitschrift für Naturforschung C 64 (9-10), 619-625
Synthesis and characterization of water-soluble palladium (II)-functionalized diphosphine complexes
M Sunjuk, M Al-Noaimi, GA Sheikha, E Lindner, B El-Eswed, K Sweidan
Polyhedron 28 (8), 1393-1398
Synthesis of Unsaturated Analogues of 9-[2 (Phosphono-Methoxy) Propyl] Guanine as Antiviral Agents
P Franchetti, GA Sheikha, P Perlini, F Farhat, M Grifantini, G Perra, C Milia, ...
Nucleosides, Nucleotides & Nucleic Acids 16 (10-11), 1921-1932
Some sulfonamide drugs inhibit ATPase activity of heat shock protein 90: investigation by docking simulation and experimental validation
GA Sheikha, MA Al-Sha’er, MO Taha
Journal of enzyme inhibition and medicinal chemistry 26 (5), 603-609
Antihyperlipidemic properties of novel N-(benzoylphenyl)-5-substituted-1H-indole-2-carboxamides in Triton WR-1339-induced hyperlipidemic rats
Y Al-Hiari, G Shattat, T Al-Qirim, W El-Huneidi, GA Sheikha, S Hikmat
Molecules 16 (10), 8292-8304

Ghassan Abu Sheikha, Dean of Faculty of Pharmacy at Al-Zaytoonah University (Tel 00962 64291511), e-mail: ztipc2015@zuj.edu.jo or from the conference ...

///////Ghassan Abu Sheikha,

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