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Thursday, 1 October 2015


Pratima Patil

Pratima Patil

PhD. in Biological Sciences,University of Delaware




Recently graduated with a PhD from University of Delaware. Developed 3D culture model to mimic components of the tumor micro-environment and investigate the impact of tumor cells on normal epithelial cells. Worked in the pharmaceutical R&D area for 4 years where I developed and optimized cell free and cell based assays to evaluate efficacy and potency of potential drug candidates in different assay formats.Over the years I have gained expertise in molecular biology, protein biochemistry and confocal microscopy techniques.


Research Assistant

August 2010 – Present (5 years 3 months)Wilmington,Delaware

PHD Graduate Student

University of Delaware
December 2009 – Present (5 years 11 months)United States
For my doctoral research project, I have been studying the early events that lead to tumor formation, particularly how tumor cells affect normal epithelial cell morphology.
Developed novel 3D assay system to study preneoplastic lumen filling in vitro and to quantify the pro-oncogenic effects of soluble E-cadherin, a tumor promoting protein fragment which is elevated in epithelial cancers.

Associate Research Scientist

Advinus Therapeutics Pvt. Ltd.
May 2007 – November 2009 (2 years 7 months)India
• Developed in vitro assays to screen for potential drug candidates against various biological targets in inflammatory diseases and metabolic disorders
• Developed secondary cell-based fluorimetric assays for measuring intracellular calcium mobilization and cAMP to screen for activity of GPCR modulators
• Developed radiometric assays to screen for modulators of metabolite transporters

Assistant Research Scientist

Advinus Therapeutics- A TATA Enterprise
December 2005 – May 2007 (1 year 6 months)India
•Routinely screened compounds in cell-free enzymatic assays using absorption and fluorescence readouts
•Gained experience in protein expression (prokaryotic systems), protein isolation and purification using various chromatography techniques


University of Delaware

Doctor of Philosophy (Ph.D.), Cell/Cellular and Molecular Biology
2010 – 2015
Dissertation Title: 'Soluble E-cadherin as a Microenvironmental Factor which Enhances Tumor Progression'

Vellore Institute of Technology

Master's degree, Biomedical Genetics
2003 – 2005


School:University Of Delaware - Newark, DE     2000 to 2003
Ph.d. in biological sciences
School:Nagpur University - Nagpur, Maharashtra     2003
Bachelor of science
School:Vellore Institute Of Technology - Vellore, Tamil Nadu
Master's in biomedical genetics
School:Chemistry In Nagpur University

University of Delaware

Map of university of delaware

vellore institute of technology
Map of vit university

Newark, United States

Map of wilmington de

////Newark, United States, vellore institute of technology, pratima patil, delaware,

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