Dr. Vasanth K Nalam
DGM-R&D at Suven Life Sciences Ltd.
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vknalam@suven.com
Summary
More than 20 years of rich experience in process research for API’s, new chemical entities (NCE’s), custom chemical synthesis (CCS) and contract research & manufacturing services (CRAMS) with reputed pharmaceutical organizations. Good understanding and analytical capabilities over various research areas (Medicinal chemistry & process research) and different business segments like APIs, CCS business.
Role and Responsibilities:
-New synthetic route identification.
-Development of non-infringing synthetic routes for Generic API’s and new chemical entities (NCE) with multiple-step chemistry and Scale-up varies therapeutic areas in a cost effective and environment friendly manner.
-Selection of cost effective suitable synthetic route for commercialization (Process research).
-Process optimization and process robustness demonstration from lab scale to commercial supplies (process development)
-Project leadership roles.
-Managing large team, team building, motivation and drive the team to achieve target.
Professional Experience:
-Complete project management includes heading a group of scientists working in various kind of projects (API, CCS)
-Providing sound technical proposals (chemistry selection, estimation of cost and timelines) & project plans for the custom synthesis and contract research for various clients.
-Responsible to meet the timeline for DMF filings as per business plan.
-Responsible for addressing the regulatory and business queries.
-Responsible for successful scale-up of technology at plant.
-Trouble shooting in Kilo lab/PP/Plant
-Identification of cost contributors and reduction of cost for better project margins and competitive advantage during the execution of projects.
Role and Responsibilities:
-New synthetic route identification.
-Development of non-infringing synthetic routes for Generic API’s and new chemical entities (NCE) with multiple-step chemistry and Scale-up varies therapeutic areas in a cost effective and environment friendly manner.
-Selection of cost effective suitable synthetic route for commercialization (Process research).
-Process optimization and process robustness demonstration from lab scale to commercial supplies (process development)
-Project leadership roles.
-Managing large team, team building, motivation and drive the team to achieve target.
Professional Experience:
-Complete project management includes heading a group of scientists working in various kind of projects (API, CCS)
-Providing sound technical proposals (chemistry selection, estimation of cost and timelines) & project plans for the custom synthesis and contract research for various clients.
-Responsible to meet the timeline for DMF filings as per business plan.
-Responsible for addressing the regulatory and business queries.
-Responsible for successful scale-up of technology at plant.
-Trouble shooting in Kilo lab/PP/Plant
-Identification of cost contributors and reduction of cost for better project margins and competitive advantage during the execution of projects.
Experience
Education
Kakatiya University
Warangal Area, India
Research Publications
Ü Process
Research and Development of Melatonin
C. Prabhakar, N.Vasanth Kumar, M. Ravikanth
Reddy, M.R. Sarma and G. Om Reddy.
Organic Process Research & Development
1999, 3, 155-160
Ü Synthesis and Biological activity of novel
Anti-bacterial Quinolones
M R Sarma, N Vasanth Kumar, A S R Prasad, S Eswaraiah, C
Prabhakar, G Om Reddy, M Sitaram Kumar, A K Sadhukhan, A Venkateswarlu & K
Anji Reddy. Indian Journal of Chemistry.
Vol. 40B, 2001, 331-335
Ü
Synthesis
of some novel ethyl 6-cyano-7-substituted-5-methyl-2-oxo-2H-pyrano
[2, 3-b] pyridine-3-carboxylate derivatives. N Vasanth Kumar & Uday C Mashelker.
Indian J Chem. 45B, 2006,
1770.
Ü
Diasteroselective
synthesis of some novel Benzopyranopyridine derivatives.
Pradeep K
Mohakhud, Sujeet Kumar, N Vasanth Kumar, V. Ravi Kumar, J. Moses Babu, K. Vyas
and G Om Reddy, Beilstein Journal of Organic Chemistry 2006, 2:25
Ü Synthesis
of novel 1,2,4-oxadiazole heterocyclic compounds contain
2-H-pyranopyridine-2-one moiety and related compounds. N Vasanth Kumar & Uday C Mashelker. Indian
Journal of Chemistry, 46B, 2007, 216.
Ü Synthesis
of novel 3-substituted derivatives of 2H-pyrano[2,3-b]pyridine-2-one
moiety
N Vasanth Kumar & Uday C Mashelkar. Journal of Indian Chemical Society, Vol. 84,October 2007, 1048-1051.
Ü Synthesis
of new heterocyclic compounds containing 2H-pyrano-[2,3-b]pyridine-2-one moiety
N
Vasanth Kumar & Uday C Mashelkar,
Indian Journal of Heterocyclic Chemistry, Vol. 17, July-Sept., 2007, 99-100
Ü
Synthesis
of some novel 1,2,4-triazolo[4,3-a]-2H-pyrano[3,2-e] pyridine derivatives.
N
Vasanth Kumar & Uday C Mashelkar, Heterocyclic
Communications, Vol. 13, No. 4, 2007, 211-214.
Patents & Patent Applications
Ü A novel method for the preparation of aryl piperazinyl
heterocyclic compounds.
Tyagi Om dutt;
Srivastava Tushar kumar; Chauhan Yogendra Kumar; Nalam Vasanth Kumar
WO
2006/011157 A2.
Ü Preparation of [2-Methyl-5Phenyl-3-(Piperazin-1-yl
Methyl)] Pyrrole Derivatives
Arora
Sudershan Kumar; Sinha Neelima; Jain Sanjay; Upadhayaya Ram Shankar; Tyagi Om
Dutt; Nalam
Vasanth;
Chauhan Yogendra Kumar WO 2006/ 109323 A1.
Ü Preparation of
(2-methyl-5-phenyl-3-(piperazin-1-ylmethyl)) pyrrole derivatives
Nalam Vasanth; Chauhan yogendra Kumar;
Upadhayaya Ram Shankar; Sinha Neelima; Jain Sanjay;
Tyagi Om Dutt; Arora Sudershan Kumar
AU2006233943
Ü Novel
Method for the Preparation of Aryl Piperazinyl-Heterocyclic Compounds
Tyagi Om D;
Srivastava Tushar k ; Chauhan Yogendra K ; Nalam Vasanth K US2007238877
Ü Improved Process for the preparation of
7-amino-3-alkyl-3-cephem-4-carboxylic acid
compounds. Application 961/MUM/2004 published 2007-04-27, filed
2004-09-08
Ü A process for the preparation of novel crystalline form
of Ziprasidone base.
Application 1118/MUM/2004 published 2007-06-08,
filed 2004-10-19
Ü A process for the preparation of novel crystalline form
of Ziprasidone Hydrochloride Monohydrate Salt.
Application
1119/MUM/2004 published 2007-06-08, filed 2004-10-19.
Ü Improved Process for the manufacture of Ziprasidone.
Tyagi Om D;
Srivastava Tushar k ; Chauhan Yogendra K ; Nalam Vasanth K, Patil Sadanand Nilkanth.
WO2010010566A1.
HIS FAMILY
VASANTH KUMAR
HYDERABAD
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